Literature DB >> 23144527

Clustering of High Throughput Gene Expression Data.

Harun Pirim1, Burak Ekşioğlu, Andy Perkins, Cetin Yüceer.   

Abstract

High throughput biological data need to be processed, analyzed, and interpreted to address problems in life sciences. Bioinformatics, computational biology, and systems biology deal with biological problems using computational methods. Clustering is one of the methods used to gain insight into biological processes, particularly at the genomics level. Clearly, clustering can be used in many areas of biological data analysis. However, this paper presents a review of the current clustering algorithms designed especially for analyzing gene expression data. It is also intended to introduce one of the main problems in bioinformatics - clustering gene expression data - to the operations research community.

Entities:  

Year:  2012        PMID: 23144527      PMCID: PMC3491664          DOI: 10.1016/j.cor.2012.03.008

Source DB:  PubMed          Journal:  Comput Oper Res        ISSN: 0305-0548            Impact factor:   4.008


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