| Literature DB >> 23143365 |
Theresa Judge1, Jason M Pogue, Dror Marchaim, Kevin Ho, Srinivasa Kamatam, Shakila Parveen, Namita Tiwari, Priyanka Nanjireddy, Suchitha Bheemreddy, Caitlin Biedron, Sagar Mallikethi Lepakshi Reddy, Vijaykumar Khammam, Indu K Chalana, Rajachendra Shekher Tumma, Vicki Collins, Adnan Yousuf, Paul R Lephart, Emily T Martin, Michael J Rybak, Keith S Kaye, Kayoko Hayakawa.
Abstract
A retrospective case-case control study was conducted, including 60 cases with daptomycin-nonsusceptible vancomycin-resistant enterococci (DNS-VRE) matched to cases with daptomycin-susceptible VRE and to uninfected controls (1∶1∶3 ratio). Immunosuppression, presence of comorbid conditions, and prior exposure to antimicrobials were independent predictors of DNS-VRE, although prior daptomycin exposure occurred rarely. In summary, a case-case control study identified independent risk factors for the isolation of DNS-VRE: immunosuppression, multiple comorbid conditions, and prior exposures to cephalosporines and metronidazole.Entities:
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Year: 2012 PMID: 23143365 DOI: 10.1086/668438
Source DB: PubMed Journal: Infect Control Hosp Epidemiol ISSN: 0899-823X Impact factor: 3.254