The OECD guidelines for the testing of chemicals and pesticides.

In many countries the process of toxicity testing of environmental chemicals is ruled by a framework of OECD guidelines. The present paper will give an overview over the relevant OECD guidelines and guidance documents and mainly focus on methodological issues related to the prenatal toxicity testing guideline. Relevant guideline text will be provided, and practical recommendations will be given both for critical issues of experimental methodology and data interpretation.