Literature DB >> 231232

High-affinity binding of [3H]muscimol to subcellular particles of a neurone-enriched culture of embryonic rat brain.

F V DeFeudis, L Ossola, G Schmitt, P Mandel.   

Abstract

High-affinity, Na+-independent binding of [3H]muscimol (KB approximately equal to 1.6 x 10(-8) M; Bmax approximately equal to 0.14 nmol/g pellet) occurred to a frozen-thawed particulate fraction of 74-h-old neurone-enriched cultures prepared from the cerebra of 12-13-day-old rat embryos. This finding provides evidence that GABA-receptors exist on cultured neurones which contain only a few synaptic connections.

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Year:  1979        PMID： 231232     DOI： 10.1016/0304-3940(79)96147-0

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  6 in total

1.  Benzodiazepine receptor sites in the chick optic lobe: development and pharmacological characterization.

Authors:  M C Gravielle; S Fiszer de Plazas
Journal:  Neurochem Res       Date:  1991-01       Impact factor: 3.996

2.  GABA-agonists induce the formation of low-affinity GABA-receptors on cultured cerebellar granule cells via preexisting high affinity GABA receptors.

Authors:  B Belhage; E Meier; A Schousboe
Journal:  Neurochem Res       Date:  1986-04       Impact factor: 3.996

3.  Ligand-binding studies on GABA receptors--relation to physiology and behavior.

Authors:  F V DeFeudis
Journal:  Neurochem Res       Date:  1984-03       Impact factor: 3.996

4.  Development of [3H]muscimol binding to subcellular particles of a culture of mouse brain.

Authors:  L L Sarliève; F V DeFeudis; L Ossola; V Varga; P Mandel
Journal:  Neurochem Res       Date:  1980-12       Impact factor: 3.996

5.  Binding of [3H]GABA and [3H]muscimol to subcellular particles of a neurone-enriched culture of mouse brain.

Authors:  L L Sarliève; F V DeFeudis; L Ossola; P Mandel
Journal:  Experientia       Date:  1980-05-15

6.  Autoradiographic localization of 3H-GABA and 3H-muscimol binding in rat cerebellar cultures.

Authors:  E Hösli; L Hösli
Journal:  Exp Brain Res       Date:  1980-01       Impact factor: 1.972
  6 in total

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