Literature DB >> 6261175

Development of [3H]muscimol binding to subcellular particles of a culture of mouse brain.

L L Sarliève, F V DeFeudis, L Ossola, V Varga, P Mandel.   

Abstract

"Specific" binding of [3H]muscimol (11.5 nM) related to GABA receptors, occurred in subcellular particles prepared from 4-, 8-, and 12-day cultures of embryonic (14- to 15-day-old) mouse cerebrum, but not to particles prepared from 20- to 45-day cultures. Phase-contrast microscopy revealed that the presence of neuronal elements (neuroblasts, neurites) paralleled the binding of [3H]muscimol. Further evidence is thus provided for using high-affinity [3H]muscimol binding as a "neuronal marker."

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Year:  1980        PMID： 6261175     DOI： 10.1007/bf00964963

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  18 in total

1.  Localization of acetylcholine receptors during synaptogenesis in retina.

Authors:  Z Vogel; M Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

2.  High-affinity binding of [3H]muscimol to subcellular particles of a neurone-enriched culture of embryonic rat brain.

Authors:  F V DeFeudis; L Ossola; G Schmitt; P Mandel
Journal:  Neurosci Lett       Date:  1979-10       Impact factor: 3.046

3.  Muscimol binding in rat brain: association with synaptic GABA receptors.

Authors:  K Beaumont; W S Chilton; H I Yamamura; S J Enna
Journal:  Brain Res       Date:  1978-06-09       Impact factor: 3.252

Review 4.  Neuropharmacology of amino acid inhibitory transmitters.

Authors:  G A Johnston
Journal:  Annu Rev Pharmacol Toxicol       Date:  1978       Impact factor: 13.820

5.  Properties of gamma-aminobutyric acid (GABA) receptor binding in rat brain synaptic membrane fractions.

Authors:  S J Enna; S H Snyder
Journal:  Brain Res       Date:  1975-12-12       Impact factor: 3.252

6.  Evidence for two types of binding of 3H-gaba and 3H-muscimol in rat cerebral cortex and cerebellum.

Authors:  M Herschel; R J Baldessarini
Journal:  Life Sci       Date:  1979-05-14       Impact factor: 5.037

7.  Preferential "binding" of gamma-aminobutyric acid and glycine to synaptosome-enriched fractions of rat cerebral cortex and spinal cord.

Authors:  F V DeFeudis
Journal:  Can J Physiol Pharmacol       Date:  1974-04       Impact factor: 2.273

8.  Substrate specificity of [3H]muscimol binding to a particulate fraction of a neuron-enriched culture of embryonic rat brain.

Authors:  F V DeFeudis; L Ossola; G Schmitt; P Mandel
Journal:  J Neurochem       Date:  1980-04       Impact factor: 5.372

9.  Binding of [3H]GABA and [3H]muscimol to subcellular particles of a neurone-enriched culture of mouse brain.

Authors:  L L Sarliève; F V DeFeudis; L Ossola; P Mandel
Journal:  Experientia       Date:  1980-05-15

10.  Na+-independent binding of [3H]GABA and [3H]muscimol to subcellular particles of neural primary cultures and whole brain.

Authors:  F V DeFeudis; L Ossola; G Schmitt; P Wolff; P Mandel
Journal:  J Neurochem       Date:  1980-01       Impact factor: 5.372
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