Literature DB >> 6244172

Autoradiographic localization of 3H-GABA and 3H-muscimol binding in rat cerebellar cultures.

E Hösli, L Hösli.   

Abstract

Autoradiographic studies were conducted on the binding of 3H-GABA and 3H-muscimol in cultures of rat cerebellum. Binding sites for both substances were observed on many cerebellar neurones, such as Purkinje cells and interneurones, but not on glial cells. Binding of 3H-GABA and 3H-muscimol was inhibited by unlabelled GABA and by the GABA antagonist bicuculline.

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Year:  1980        PMID： 6244172     DOI： 10.1007/bf00236746

Source DB:  PubMed          Journal:  Exp Brain Res        ISSN： 0014-4819            Impact factor:   1.972


  18 in total

1.  Uptake and metabolism of gamma-aminobutyric acid by neurones and glial cells.

Authors:  L L Iversen; J S Kelly
Journal:  Biochem Pharmacol       Date:  1975-05-01       Impact factor: 5.858

2.  High-affinity binding of [3H]muscimol to subcellular particles of a neurone-enriched culture of embryonic rat brain.

Authors:  F V DeFeudis; L Ossola; G Schmitt; P Mandel
Journal:  Neurosci Lett       Date:  1979-10       Impact factor: 3.046

3.  Muscimol binding in rat brain: association with synaptic GABA receptors.

Authors:  K Beaumont; W S Chilton; H I Yamamura; S J Enna
Journal:  Brain Res       Date:  1978-06-09       Impact factor: 3.252

4.  Ultrastructural localization of gamma-aminobutyric acid receptors in the mammalian central nervous system by means of [3H]muscimol binding.

Authors:  V Chan-Palay; S L Palay
Journal:  Proc Natl Acad Sci U S A       Date:  1978-06       Impact factor: 11.205

5.  Use of 3H-muscimol for GABA receptor studies.

Authors:  S R Snodgrass
Journal:  Nature       Date:  1978-06-01       Impact factor: 49.962

6.  Autoradiographic identification of cerebral and cerebellar cortical neurons accumulating labeled gamma-aminobutyric acid ( 3 H-GABA).

Authors:  T Hökfelt; A Ljungdahl
Journal:  Exp Brain Res       Date:  1972       Impact factor: 1.972

7.  Muscimol uptake, release and binding in rat brain slices.

Authors:  G A Johnston; S M Kennedy; D Lodge
Journal:  J Neurochem       Date:  1978-12       Impact factor: 5.372

8.  Localization of gamma-aminobutyric acid receptor binding in the mammalian cerebellum: high levels in granule layer and depletion in agranular cerebella of mutant mice.

Authors:  R W Olsen; K Mikoshiba
Journal:  J Neurochem       Date:  1978-06       Impact factor: 5.372

9.  GABA receptor binding with 3H-muscimol in calf cerebellum.

Authors:  M J Leach; J A Wilson
Journal:  Eur J Pharmacol       Date:  1978-04-01       Impact factor: 4.432

10.  Autoradiographic localization of gamma-aminobutyric acid receptors in the rat central nervous system by using [3H]muscimol.

Authors:  V Chan-Palay
Journal:  Proc Natl Acad Sci U S A       Date:  1978-02       Impact factor: 11.205
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  4 in total

1.  Light and electron microscopic localization of GABAA-receptors on cultured cerebellar granule cells and astrocytes using immunohistochemical techniques.

Authors:  G H Hansen; E Hösli; B Belhage; A Schousboe; L Hösli
Journal:  Neurochem Res       Date:  1991-03       Impact factor: 3.996

2.  Immunohistochemical studies on the cellular localization of GABAA-receptors in explant cultures of rat central nervous system using a monoclonal antibody.

Authors:  E Hösli; L Hösli
Journal:  Exp Brain Res       Date:  1990       Impact factor: 1.972

Review 3.  Pharmacology of GABA-mediated inhibition of spinal cord neurons in vivo and in primary dissociated cell culture.

Authors:  R L Macdonald; A B Young
Journal:  Mol Cell Biochem       Date:  1981-08-11       Impact factor: 3.396

4.  Evidence that the depolarization of glial cells by inhibitory amino acids is caused by an efflux of K+ from neurones.

Authors:  L Hösli; E Hösli; P F Andrès; H Landolt
Journal:  Exp Brain Res       Date:  1981       Impact factor: 1.972
  4 in total

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