Literature DB >> 231202

Lack of detectable nuclease activity in highly purified preparations of murine fibroblast interferon.

J N Wood.   

Abstract

The size distribution of radiolabeled mouse C-243 cell poly-A containing RNA, and SV40 DNA was analyzed electrophoretically before and after incubation with high concentrations of electrophoretically pure murine fibroblast interferon. Using this sensitive assay, no evidence for any nuclease activity directly associated with interferon could be found, under a wide variety of incubation conditions.

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Year:  1979        PMID： 231202     DOI： 10.1007/bf00782899

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  6 in total

1.  Interferon: purification and initial characterization from human diploid cells.

Authors:  E Knight
Journal:  Proc Natl Acad Sci U S A       Date:  1976-02       Impact factor: 11.205

2.  Interferon action II. Membrane-bound alkaline ribonuclease activity in chick embryo cells manifesting interferon-mediated interference.

Authors:  P I Marcus; T M Terry; S Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

3.  Purification of human fibroblast interferon by zinc chelate affinity chromatography.

Authors:  V G Edy; A Billiau; P de Somer
Journal:  J Biol Chem       Date:  1977-09-10       Impact factor: 5.157

4.  Relationship between interferon production and interferon messenger RNA synthesis in human fibroblasts.

Authors:  N B Raj; P M Pitha
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205

5.  Interaction of interferon with tRNA.

Authors:  M N Thang; J De Maeyer-Guignard; E De Maeyer
Journal:  FEBS Lett       Date:  1977-08-15       Impact factor: 4.124

6.  Purification of mouse interferon by sequential affinity chromatography on poly(U)--and antibody--agarose columns.

Authors:  J De Maeyer-Guignard; M G Tovey; I Gresser; E De Maeyer
Journal:  Nature       Date:  1978-02-16       Impact factor: 49.962
  6 in total

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