Literature DB >> 23105667

Age related changes in lipid peroxidation and antioxidants in elderly people.

V Prashant Akila1, H Harishchandra, Vivian D'souza, Benedicta D'souza.   

Abstract

Advanced age is associated with an accumulation of free radical damage, which leads to physiological and clinical modifications. Age related changes resulting from free radical reactions include increasing levels of lipid peroxides, alterations in enzyme activities and greater osmotic fragility. The present study was conducted to estimate the level of lipid peroxidation product-Malondialdehyde and antioxidants Catalase and Glutathione in elderly people. An increase in lipid peroxidation and decrease in antioxidants was observed in normal elderly people. Highly significant increase in MDA and decrease in antioxidants was observed in elderly people when complicated with diabetes and hypertension. Supplementation of antioxidants may prevent further oxidative injury in elderly people.

Entities:  

Keywords:  Antioxidants; Elderly people; Lipid peroxidation

Year:  2007        PMID： 23105667      PMCID： PMC3454250          DOI： 10.1007/BF02912896

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


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  9 in total

1.  Biomedical studies on lipid peroxidation and erythrocyte fragility during the process of aging.

Authors:  Arun Kumar
Journal:  Asian Pac J Trop Biomed       Date:  2011-01

2.  Change in Oxidative Stress of Normotensive Elderly Subjects Following Lifestyle Modifications.

Authors:  Anubhav Bhatnagar; Yogesh Tripathi; Anoop Kumar
Journal:  J Clin Diagn Res       Date:  2016-09-01

Review 3.  Propagation of age-related diseases due to the changes of lipid peroxide and antioxidant levels in elderly people: A narrative review.

Authors:  Julfikar Ali; Md Abdul Aziz; Md Mamun Or Rashid; Mohammad Anwarul Basher; Mohammad Safiqul Islam
Journal:  Health Sci Rep       Date:  2022-05-23

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Authors:  Hakan Yavuzer; Serap Yavuzer; Mahir Cengiz; Hayriye Erman; Alper Doventas; Huriye Balci; Deniz Suna Erdincler; Hafize Uzun
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Review 5.  Advanced Collaborative Emissions Study Auxiliary Findings on 2007-Compliant Diesel Engines: A Comparison With Diesel Exhaust Genotoxicity Effects Prior to 2007.

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Journal:  Environ Health Insights       Date:  2017-06-19

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Authors:  Adiv A Johnson; Alexandra Stolzing
Journal:  Aging Cell       Date:  2019-09-27       Impact factor: 9.304

7.  Age- and Sex-Dependent Changes of Free Circulating Blood Metabolite and Lipid Abundances, Correlations, and Ratios.

Authors:  Francesca Di Cesare; Claudio Luchinat; Leonardo Tenori; Edoardo Saccenti
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2022-05-05       Impact factor: 6.591

8.  Selected Oxidative Stress Markers in Colorectal Cancer Patients in Relation to Primary Tumor Location-A Preliminary Research.

Authors:  Karolina Janion; Elżbieta Szczepańska; Ewa Nowakowska-Zajdel; Joanna Strzelczyk; Angelika Copija
Journal:  Medicina (Kaunas)       Date:  2020-01-21       Impact factor: 2.430

9.  Reversal of age-associated oxidative stress in mice by PFT, a novel kefir product.

Authors:  Mamdooh Ghoneum; Shaymaa Abdulmalek; Deyu Pan
Journal:  Int J Immunopathol Pharmacol       Date:  2020 Jan-Dec       Impact factor: 3.219
  9 in total

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