Literature DB >> 23103510

Detailed structural analysis of the O-polysaccharide expressed by Burkholderia thailandensis E264.

Christian Heiss1, Mary N Burtnick, Ian Black, Parastoo Azadi, Paul J Brett.   

Abstract

O-polysaccharide (n class="Chemical">OPS) was isolated from purified Burkholderia thailandensis E264 lipopolysaccharide by mild-acid hydrolysis and gel-permeation chromatography. Glycosyl composition and methylation analyses along with 1D and 2D (1)H and (13)C NMR spectroscopy experiments revealed that the OPS antigen was an unbranched heteropolymer with the following structure: [structure: see text] Collectively, these results suggest that B. thailandensis OPS is structurally more complex than B. pseudomallei OPS and provide evidence of the signal used by B. thailandensis to terminate chain elongation.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 23103510      PMCID: PMC3496072          DOI: 10.1016/j.carres.2012.09.027

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


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