Literature DB >> 23090781

Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes.

Yun Zhao1, Josephine L C Howe, Zhang Yu, David Tai Leong, Justin Jang Hann Chu, Joachim Say Chye Loo, Kee Woei Ng.   

Abstract

Understanding the mechanisms of cell-nanomaterial interactions is vital in harnessing the potential of using nanomaterials in biomedical applications. By immuno-labeling of LC3 and TEM analysis, it is found that titanium dioxide nanoparticles are internalized by human keratinocytes and induce autophagy. Autophagy appears to play a cytoprotective role in response to toxicity influence exerted by the nanoparticles.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 23090781     DOI： 10.1002/smll.201201363

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  29 in total

Review 1.  Nanoparticle Interactions with the Tumor Microenvironment.

Authors:  Yanyan Huai; Md Nazir Hossen; Stefan Wilhelm; Resham Bhattacharya; Priyabrata Mukherjee
Journal:  Bioconjug Chem       Date:  2019-09-05       Impact factor: 4.774

2.  Antiproliferative effects of ZnO, ZnO-MTCP, and ZnO-CuMTCP nanoparticles with safe intensity UV and X-ray irradiation.

Authors:  Susan Sadjadpour; Shahrokh Safarian; Seyed Jalal Zargar; Nader Sheibani
Journal:  Biotechnol Appl Biochem       Date:  2015-04-15       Impact factor: 2.431

3.  Nanoparticulate titanium dioxide-inhibited dendritic development is involved in apoptosis and autophagy of hippocampal neurons in offspring mice.

Authors:  Yingjun Zhou; Fashui Hong; Yusheng Tian; Xiangyu Zhao; Jie Hong; Yuguan Ze; Ling Wang
Journal:  Toxicol Res (Camb)       Date:  2017-09-20       Impact factor: 3.524

Review 4.  The use of nanoparticulates to treat breast cancer.

Authors:  Xiaomeng Tang; Welley S Loc; Cheng Dong; Gail L Matters; Peter J Butler; Mark Kester; Craig Meyers; Yixing Jiang; James H Adair
Journal:  Nanomedicine (Lond)       Date:  2017-09-04       Impact factor: 5.307

5.  Titanium dioxide nanoparticles increase inflammatory responses in vascular endothelial cells.

Authors:  Sung Gu Han; Bradley Newsome; Bernhard Hennig
Journal:  Toxicology       Date:  2013-02-01       Impact factor: 4.221

6.  Molecular and physiological responses to titanium dioxide and cerium oxide nanoparticles in Arabidopsis.

Authors:  Laxminath Tumburu; Christian P Andersen; Paul T Rygiewicz; Jay R Reichman
Journal:  Environ Toxicol Chem       Date:  2016-08-03       Impact factor: 3.742

7.  EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage.

Authors:  Shinji Kuroda; Justina Tam; Jack A Roth; Konstantin Sokolov; Rajagopal Ramesh
Journal:  Int J Nanomedicine       Date:  2014-08-08

8.  Titanium dioxide nanoparticle impact and translocation through ex vivo, in vivo and in vitro gut epithelia.

Authors:  Emilie Brun; Frédérick Barreau; Giulia Veronesi; Barbara Fayard; Stéphanie Sorieul; Corinne Chanéac; Christine Carapito; Thierry Rabilloud; Aloïse Mabondzo; Nathalie Herlin-Boime; Marie Carrière
Journal:  Part Fibre Toxicol       Date:  2014-03-25       Impact factor: 9.400

Review 9.  In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

Authors:  Moritz Nazarenus; Qian Zhang; Mahmoud G Soliman; Pablo Del Pino; Beatriz Pelaz; Susana Carregal-Romero; Joanna Rejman; Barbara Rothen-Rutishauser; Martin J D Clift; Reinhard Zellner; G Ulrich Nienhaus; James B Delehanty; Igor L Medintz; Wolfgang J Parak
Journal:  Beilstein J Nanotechnol       Date:  2014-09-09       Impact factor: 3.649

10.  Overendocytosis of gold nanoparticles increases autophagy and apoptosis in hypoxic human renal proximal tubular cells.

Authors:  Fengan Ding; Yiping Li; Jing Liu; Lei Liu; Wenmin Yu; Zhi Wang; Haifeng Ni; Bicheng Liu; Pingsheng Chen
Journal:  Int J Nanomedicine       Date:  2014-09-12
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