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Literature DB >> 31408324

Nanoparticle Interactions with the Tumor Microenvironment.

Yanyan Huai, Md Nazir Hossen, Stefan Wilhelm¹, Resham Bhattacharya, Priyabrata Mukherjee.

Abstract

Compared to normal tissues, the tumor microenvironment (TME) has a number of aberrant characteristics including hypoxia, acidosis, and vascular abnormalities. Many researchers have sought to exploit these anomalous features of the TME to develop anticancer therapies, and several nanoparticle-based cancer therapeutics have resulted. In this Review, we discuss the composition and pathophysiology of the TME, introduce nanoparticles (NPs) used in cancer therapy, and address the interaction between the TME and NPs. Finally, we outline both the potential problems that affect TME-based nanotherapy and potential strategies to overcome these challenges.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Year: 2019 PMID： 31408324 PMCID： PMC6892461 DOI： 10.1021/acs.bioconjchem.9b00448

Source DB: PubMed Journal: Bioconjug Chem ISSN： 1043-1802 Impact factor: 4.774

228 in total

Review 1. Nanoparticle design considerations for molecular imaging of apoptosis: Diagnostic, prognostic, and therapeutic value.

Authors: Ronak Savla; Tamara Minko
Journal: Adv Drug Deliv Rev Date: 2016-06-29 Impact factor: 15.470

Review 2. Synthesis, Assembly, and Applications of Hybrid Nanostructures for Biosensing.

Authors: Shuaidi Zhang; Ren Geryak; Jeffrey Geldmeier; Sunghan Kim; Vladimir V Tsukruk
Journal: Chem Rev Date: 2017-09-13 Impact factor: 60.622

3. Terminating the criminal collaboration in pancreatic cancer: Nanoparticle-based synergistic therapy for overcoming fibroblast-induced drug resistance.

Authors: Liying Wang; Xiangrui Liu; Quan Zhou; Meihua Sui; Zipeng Lu; Zhuxian Zhou; Jianbin Tang; Yi Miao; Min Zheng; Weilin Wang; Youqing Shen
Journal: Biomaterials Date: 2017-08-02 Impact factor: 12.479

Review 4. PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect.

Authors: Sarbari Acharya; Sanjeeb K Sahoo
Journal: Adv Drug Deliv Rev Date: 2010-10-20 Impact factor: 15.470

Review 5. Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.

Authors: Yunlu Dai; Can Xu; Xiaolian Sun; Xiaoyuan Chen
Journal: Chem Soc Rev Date: 2017-05-18 Impact factor: 54.564

Review 6. Diamond nanostructures for drug delivery, bioimaging, and biosensing.

Authors: Xianfeng Chen; Wenjun Zhang
Journal: Chem Soc Rev Date: 2017-02-06 Impact factor: 54.564

7. Matrix crosslinking forces tumor progression by enhancing integrin signaling.

Authors: Kandice R Levental; Hongmei Yu; Laura Kass; Johnathon N Lakins; Mikala Egeblad; Janine T Erler; Sheri F T Fong; Katalin Csiszar; Amato Giaccia; Wolfgang Weninger; Mitsuo Yamauchi; David L Gasser; Valerie M Weaver
Journal: Cell Date: 2009-11-25 Impact factor: 41.582

8. pH-responsive CAP-co-poly(methacrylic acid)-based hydrogel as an efficient platform for controlled gastrointestinal delivery: fabrication, characterization, in vitro and in vivo toxicity evaluation.

Authors: Syed Ahmed Shah; Muhammad Sohail; Muhammad Usman Minhas; Shahzeb Khan; Zahid Hussain; Arshad Mahmood; Mubeen Kousar; Asif Mahmood
Journal: Drug Deliv Transl Res Date: 2019-04 Impact factor: 4.617

9. Modulation of Macrophage Phenotype by Biodegradable Polyurethane Nanoparticles: Possible Relation between Macrophage Polarization and Immune Response of Nanoparticles.

Authors: Yen-Jang Huang; Kun-Che Hung; Huey-Shan Hung; Shan-Hui Hsu
Journal: ACS Appl Mater Interfaces Date: 2018-05-31 Impact factor: 9.229

10. Nanoparticles modulate autophagic effect in a dispersity-dependent manner.

Authors: Dengtong Huang; Hualu Zhou; Jinhao Gao
Journal: Sci Rep Date: 2015-09-23 Impact factor: 4.379

11 in total

1. Disabling partners in crime: Gold nanoparticles disrupt multicellular communications within the tumor microenvironment to inhibit ovarian tumor aggressiveness.

Authors: Yushan Zhang; Chandra Kumar Elechalawar; Wen Yang; Alex N Frickenstein; Sima Asfa; Kar-Ming Fung; Brennah N Murphy; Shailendra K Dwivedi; Geeta Rao; Anindya Dey; Stefan Wilhelm; Resham Bhattacharya; Priyabrata Mukherjee
Journal: Mater Today (Kidlington) Date: 2022-02-23 Impact factor: 26.943

Nanoparticle Interactions with the Tumor Microenvironment.

Review 1. Nanoparticle design considerations for molecular imaging of apoptosis: Diagnostic, prognostic, and therapeutic value.

Review 2. Synthesis, Assembly, and Applications of Hybrid Nanostructures for Biosensing.

3. Terminating the criminal collaboration in pancreatic cancer: Nanoparticle-based synergistic therapy for overcoming fibroblast-induced drug resistance.

Review 4. PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect.

Review 5. Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.

Review 6. Diamond nanostructures for drug delivery, bioimaging, and biosensing.

7. Matrix crosslinking forces tumor progression by enhancing integrin signaling.

8. pH-responsive CAP-co-poly(methacrylic acid)-based hydrogel as an efficient platform for controlled gastrointestinal delivery: fabrication, characterization, in vitro and in vivo toxicity evaluation.

9. Modulation of Macrophage Phenotype by Biodegradable Polyurethane Nanoparticles: Possible Relation between Macrophage Polarization and Immune Response of Nanoparticles.

10. Nanoparticles modulate autophagic effect in a dispersity-dependent manner.

1. Disabling partners in crime: Gold nanoparticles disrupt multicellular communications within the tumor microenvironment to inhibit ovarian tumor aggressiveness.

Review 2. Synthesis, Principles, and Properties of Magnetite Nanoparticles for In Vivo Imaging Applications-A Review.

Review 3. Thirty Years of Cancer Nanomedicine: Success, Frustration, and Hope.

Review 4. Nanoparticle Surface Functionalization: How to Improve Biocompatibility and Cellular Internalization.

Review 5. Atypical Renal Clearance of Nanoparticles Larger Than the Kidney Filtration Threshold.

Review 6. Metallic Nanoparticles for the Modulation of Tumor Microenvironment; A New Horizon.

7. Macrophage-Encapsulated Bioorthogonal Nanozymes for Targeting Cancer Cells.

Review 8. Gold Nanoparticles Contact with Cancer Cell: A Brief Update.

Review 9. The Effective Combination between 3D Cancer Models and Stimuli-Responsive Nanoscale Drug Delivery Systems.

Review 10. Organ-on-a-chip technology for nanoparticle research.