Literature DB >> 23089011

We can do better than effective dose for estimating or comparing low-dose radiation risks.

D J Brenner1.   

Abstract

The effective dose concept was designed to compare the generic risks of exposure to different radiation fields. More commonly these days, it is used to estimate or compare radiation-induced cancer risks. For various reasons, effective dose represents flawed science: for instance, the tissue-specific weighting factors used to calculate effective dose are a subjective mix of different endpoints; and the marked and differing age and gender dependencies for different health detriment endpoints are not taken into account. This paper suggests that effective dose could be replaced with a new quantity, 'effective risk', which, like effective dose, is a weighted sum of equivalent doses to different tissues. Unlike effective dose, where the tissue-dependent weighting factors are a set of generic, subjective committee-defined numbers, the weighting factors for effective risk are simply evaluated tissue-specific lifetime cancer risks per unit equivalent dose. Effective risk, which has the potential to be age and gender specific if desired, would perform the same comparative role as effective dose, be just as easy to estimate, be less prone to misuse, be more directly understandable, and would be based on solid science. An added major advantage is that it gives the users some feel for the actual numerical values of the radiation risks they are trying to control.
Copyright © 2012. Published by Elsevier Ltd.

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Year:  2012        PMID: 23089011     DOI: 10.1016/j.icrp.2012.07.001

Source DB:  PubMed          Journal:  Ann ICRP        ISSN: 0146-6453


  10 in total

1.  Patient-level dose monitoring in computed tomography: tracking cumulative dose from multiple multi-sequence exams with tube current modulation in children.

Authors:  Azadeh Tabari; Xinhua Li; Kai Yang; Bob Liu; Michael S Gee; Sjirk J Westra
Journal:  Pediatr Radiol       Date:  2021-09-17

Review 2.  The cumulative radiation dose paradigm in pediatric imaging.

Authors:  Donald Frush
Journal:  Br J Radiol       Date:  2021-09-14       Impact factor: 3.629

3.  Comparison of effective dose and lifetime risk of cancer incidence of CT attenuation correction acquisitions and radiopharmaceutical administration for myocardial perfusion imaging.

Authors:  A K Tootell; K Szczepura; P Hogg
Journal:  Br J Radiol       Date:  2014-07-07       Impact factor: 3.039

4.  Reconstruction of paediatric organ doses from axial CT scans performed in the 1990s - range of doses as input to uncertainty estimates.

Authors:  Hilde M Olerud; Benthe Toft; Silje Flatabø; Andreas Jahnen; Choonsik Lee; Isabelle Thierry-Chef
Journal:  Eur Radiol       Date:  2016-01-23       Impact factor: 5.315

5.  The communication of the radiation risk from CT in relation to its clinical benefit in the era of personalized medicine: part 1: the radiation risk from CT.

Authors:  Sjirk J Westra
Journal:  Pediatr Radiol       Date:  2014-10-11

6.  The communication of the radiation risk from CT in relation to its clinical benefit in the era of personalized medicine: part 2: benefits versus risk of CT.

Authors:  Sjirk J Westra
Journal:  Pediatr Radiol       Date:  2014-10-11

7.  Breast-iRRISC: a novel model for predicting the individualised lifetime risk of radiation-induced breast cancer from a single screening event.

Authors:  Sahand Hooshmand; Warren M Reed; Mo'ayyad E Suleiman; Patrick C Brennan
Journal:  Br J Radiol       Date:  2020-10-08       Impact factor: 3.039

Review 8.  Magnetic resonance angiography for the primary diagnosis of pulmonary embolism: A review from the international workshop for pulmonary functional imaging.

Authors:  Nanae Tsuchiya; Edwin Jr van Beek; Yoshiharu Ohno; Hiroto Hatabu; Hans-Ulrich Kauczor; Andrew Swift; Jens Vogel-Claussen; Jürgen Biederer; James Wild; Mark O Wielpütz; Mark L Schiebler
Journal:  World J Radiol       Date:  2018-06-28

Review 9.  A restatement of the natural science evidence base concerning the health effects of low-level ionizing radiation.

Authors:  Angela R McLean; Ella K Adlen; Elisabeth Cardis; Alex Elliott; Dudley T Goodhead; Mats Harms-Ringdahl; Jolyon H Hendry; Peter Hoskin; Penny A Jeggo; David J C Mackay; Colin R Muirhead; John Shepherd; Roy E Shore; Geraldine A Thomas; Richard Wakeford; H Charles J Godfray
Journal:  Proc Biol Sci       Date:  2017-09-13       Impact factor: 5.349

10.  Effective dose in medicine.

Authors:  C J Martin
Journal:  Ann ICRP       Date:  2020-11-04
  10 in total

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