| Literature DB >> 23083817 |
Janki Prasad1, Atul Shrivastava, A K Khanna, G Bhatia, S K Awasthi, T Narender.
Abstract
In continuation of our drug discovery program on Indian medicinal plants, we isolated bioactive compounds (1-5) from the leaves of Calophyllum inophyllum and evaluated their antidyslipidemic activity in triton induced hyperlipidemia model. The calophyllic acid (1A) and isocalophyllic acid (1B) mixture, canophyllic acid (4) and amentoflavone (5) showed dose dependent lipid lowering activity in in vivo experiments. The compounds 1A+1B mixture and 3 also showed good in vitro antioxidant activity.Entities:
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Year: 2012 PMID： 23083817 DOI： 10.1016/j.phymed.2012.09.001
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340