Literature DB >> 33573143

Improving the Antioxidant Properties of Calophyllum inophyllum Seed Oil from French Polynesia: Development and Biological Applications of Resinous Ethanol-Soluble Extracts.

Mathieu Cassien1,2,3, Anne Mercier1, Sophie Thétiot-Laurent1, Marcel Culcasi1, Emilie Ricquebourg1, Alice Asteian1, Gaëtan Herbette4, Jean-Pierre Bianchini2, Phila Raharivelomanana2, Sylvia Pietri1.   

Abstract

class="Chemical">Tamanu oil from pan class="Species">Calophyllum inophyllum L. has long been used in traditional medicine. Ethanol extraction was found the best strategy for recovering bioactive compounds from the resin part of Tamanu oil, yielding two neutral and acidic resins fractions with high phenolics, flavonoids and pyranocoumarins concentrations. A further cascade of LPLC/HPLC separations of neutral and acidic resin fractions allowed identifying fifteen metabolites, and among them, calanolide D and 12-oxocalanolide A (both in neutral fraction) were first identified from a natural source. All these extracts, subfractions and isolated metabolites demonstrated increased free radical scavenging, antioxidant, anti-inflammatory, antimicrobial and antimycobacterial activity compared to Tamanu oil and its de-resinated lipid phase. Overall, these results could promote resinous ethanol-soluble Tamanu oil extracts as a useful multifaceted and renewable medicinal resource.

Entities:  

Keywords:  Calophyllum inophyllum L.; EPR spin trapping; Tamanu oil; UV protection; anti-inflammatory; antimicrobial; ethanol-soluble resin extracts; lipophilic antioxidants; phenolics; pyranocoumarins

Year:  2021        PMID： 33573143      PMCID： PMC7910904          DOI： 10.3390/antiox10020199

Source DB:  PubMed          Journal:  Antioxidants (Basel)        ISSN： 2076-3921


  46 in total

1.  Antimicrobial and cytotoxic agents from Calophyllum inophyllum.

Authors:  Marie C Yimdjo; Anatole G Azebaze; Augustin E Nkengfack; A Michele Meyer; Bernard Bodo; Zacharias T Fomum
Journal:  Phytochemistry       Date:  2004-10       Impact factor: 4.072

2.  On the vasoprotective mechanisms underlying novel β-phosphorylated nitrones: Focus on free radical characterization, scavenging and NO-donation in a biological model of oxidative stress.

Authors:  Mathieu Cassien; Consuelo Petrocchi; Sophie Thétiot-Laurent; Maxime Robin; Emilie Ricquebourg; Chouaib Kandouli; Alice Asteian; Antal Rockenbauer; Anne Mercier; Marcel Culcasi; Sylvia Pietri
Journal:  Eur J Med Chem       Date:  2016-04-29       Impact factor: 6.514

3.  Combining in vitro, in vivo and in silico approaches to evaluate nutraceutical potentials and chemical fingerprints of Moltkia aurea and Moltkia coerulea.

Authors:  Gokhan Zengin; Ramazan Ceylan; Jelena Katanić; Adriano Mollica; Abdurrahman Aktumsek; Tatjana Boroja; Sanja Matić; Vladimir Mihailović; Snežana Stanić; Zaahira Aumeeruddy-Elalfi; Mustafa Abdullah Yilmaz; Mohamad Fawzi Mahomoodally
Journal:  Food Chem Toxicol       Date:  2017-04-05       Impact factor: 6.023

4.  Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers.

Authors:  P Cos; L Ying; M Calomme; J P Hu; K Cimanga; B Van Poel; L Pieters; A J Vlietinck; D Vanden Berghe
Journal:  J Nat Prod       Date:  1998-01       Impact factor: 4.050

5.  Antidiabetic, antioxidant and anti inflammatory properties of water and n-butanol soluble extracts from Saharian Anvillea radiata in high-fat-diet fed mice.

Authors:  Chouaib Kandouli; Mathieu Cassien; Anne Mercier; Caroline Delehedde; Emilie Ricquebourg; Pierre Stocker; Mourad Mekaouche; Zineb Leulmi; Aicha Mechakra; Sophie Thétiot-Laurent; Marcel Culcasi; Sylvia Pietri
Journal:  J Ethnopharmacol       Date:  2017-06-30       Impact factor: 4.360

6.  Structural analogues of the calanolide anti-HIV agents. Modification of the trans-10,11-dimethyldihydropyran-12-ol ring (ring C).

Authors:  D E Zembower; S Liao; M T Flavin; Z Q Xu; T L Stup; R W Buckheit; A Khilevich; A A Mar; A K Sheinkman
Journal:  J Med Chem       Date:  1997-03-14       Impact factor: 7.446

7.  Chemical resolution of +/- -calanolide A, +/- -cordatolide A and their 11-demethyl analogues.

Authors:  Tao Ma; Qi Gao; Zhiwei Chen; Lin Wang; Gang Liu
Journal:  Bioorg Med Chem Lett       Date:  2007-12-10       Impact factor: 2.823

8.  Structures of new secofriedelane and friedelane acids from Calophyllum inophyllum of French Polynesia.

Authors:  F Laure; G Herbette; R Faure; J P Bianchini; P Raharivelomanana; B Fogliani
Journal:  Magn Reson Chem       Date:  2005-01       Impact factor: 2.447

9.  Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis.

Authors:  Ze-Qi Xu; William W Barrow; William J Suling; Louise Westbrook; Esther Barrow; Yuh-Meei Lin; Michael T Flavin
Journal:  Bioorg Med Chem       Date:  2004-03-01       Impact factor: 3.641

10.  In vivo antiarthritic activity of the ethanol extracts of stem bark and seeds of Calophyllum inophyllum in Freund's complete adjuvant induced arthritis.

Authors:  Senthamil Selvan Perumal; Sanmuga Priya Ekambaram; T Dhanam
Journal:  Pharm Biol       Date:  2016-09-05       Impact factor: 3.503
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  2 in total

1.  Novel Sterically Crowded and Conformationally Constrained α-Aminophosphonates with a Near-Neutral pKa as Highly Accurate 31P NMR pH Probes. Application to Subtle pH Gradients Determination in Dictyostelium discoideum Cells.

Authors:  Caroline Delehedde; Marcel Culcasi; Emilie Ricquebourg; Mathieu Cassien; Didier Siri; Bruno Blaive; Sylvia Pietri; Sophie Thétiot-Laurent
Journal:  Molecules       Date:  2022-07-14       Impact factor: 4.927

Review 2.  Potential of Tamanu (Calophyllum inophyllum) Oil for Atopic Dermatitis Treatment.

Authors:  Amadeus Pribowo; Jyothsna Girish; Marsia Gustiananda; Rakrya Galih Nandhira; Pietradewi Hartrianti
Journal:  Evid Based Complement Alternat Med       Date:  2021-12-26       Impact factor: 2.629
  2 in total

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