INTRODUCTION: With the onset of frailty, there is often a rapid, progressive, and self- perpetuating downward spiral towards death. Frailty has enormous impact on acute hospital care and has been shown to be a more effective predictor of mortality than conventional clinical measures. METHODS: Hospitalized older patients admitted in medical wards at a teaching public hospital were studied to determine the prevalence of frailty; its association with anemia, congestive heart failure, clinically active tuberculosis and cognitive impairment; as well as its impact upon short-term outcome. RESULTS: A total of 250 older hospitalized patients were included, and their frailty status was assessed using Fried's criteria. Of these, 83 (33.2%) patients were frail, with frailty found to be significantly associated with increasing age. A lower mean level of haemoglobin (p, 0.002), higher chance of congestive heart failure (p, <0.001), lower mean MMSE score (p, <0.001), was found in frail older patients. Frail subjects had a higher median hospital stay. There were total of 5 deaths, all among the frail group. CONCLUSION: Our study showed that almost a third of hospitalized older patients are frail, and have anemia, higher frequency of CHF, cognitive impairment, longer hospital stay and higher mortality.
INTRODUCTION: With the onset of frailty, there is often a rapid, progressive, and self- perpetuating downward spiral towards death. Frailty has enormous impact on acute hospital care and has been shown to be a more effective predictor of mortality than conventional clinical measures. METHODS: Hospitalized older patients admitted in medical wards at a teaching public hospital were studied to determine the prevalence of frailty; its association with anemia, congestive heart failure, clinically active tuberculosis and cognitive impairment; as well as its impact upon short-term outcome. RESULTS: A total of 250 older hospitalized patients were included, and their frailty status was assessed using Fried's criteria. Of these, 83 (33.2%) patients were frail, with frailty found to be significantly associated with increasing age. A lower mean level of haemoglobin (p, 0.002), higher chance of congestive heart failure (p, <0.001), lower mean MMSE score (p, <0.001), was found in frail older patients. Frail subjects had a higher median hospital stay. There were total of 5 deaths, all among the frail group. CONCLUSION: Our study showed that almost a third of hospitalized older patients are frail, and have anemia, higher frequency of CHF, cognitive impairment, longer hospital stay and higher mortality.
Authors: K E Covinsky; J T King; L M Quinn; R Siddique; R Palmer; D M Kresevic; R H Fortinsky; J Kowal; C S Landefeld Journal: J Am Geriatr Soc Date: 1997-06 Impact factor: 5.562
Authors: F Cacciatore; P Abete; F Mazzella; L Viati; D Della Morte; D D'Ambrosio; G Gargiulo; G Testa; D Santis; G Galizia; N Ferrara; F Rengo Journal: Eur J Clin Invest Date: 2005-12 Impact factor: 4.686
Authors: Quin E Denfeld; Kerri Winters-Stone; James O Mudd; Jill M Gelow; Sawsan Kurdi; Christopher S Lee Journal: Int J Cardiol Date: 2017-02-10 Impact factor: 4.164
Authors: Alexander Bennett; Danijela Gnjidic; Mark Gillett; Peter Carroll; Slade Matthews; Kristina Johnell; Johan Fastbom; Sarah Hilmer Journal: Drugs Aging Date: 2014-03 Impact factor: 3.923
Authors: P Forti; F Maioli; E Zagni; T Lucassenn; L Montanari; B Maltoni; G Luca Pirazzoli; G Bianchi; M Zoli Journal: J Nutr Health Aging Date: 2014-12 Impact factor: 4.075
Authors: M Ritt; C Schwarz; V Kronawitter; A Delinic; L C Bollheimer; K G Gassmann; C C Sieber Journal: J Nutr Health Aging Date: 2015-12 Impact factor: 4.075
Authors: K Palmer; D L Vetrano; A Marengoni; A M Tummolo; E R Villani; N Acampora; R Bernabei; G Onder Journal: J Nutr Health Aging Date: 2018 Impact factor: 4.075
Authors: Matthew R Baldwin; M Cary Reid; Amanda A Westlake; John W Rowe; Evelyn C Granieri; Hannah Wunsch; Thuy-Tien Dam; Daniel Rabinowitz; Nathan E Goldstein; Mathew S Maurer; David J Lederer Journal: J Crit Care Date: 2014-01-06 Impact factor: 3.425