Literature DB >> 12425952

The mortality rate as a function of accumulated deficits in a frailty index.

Arnold B Mitnitski1, Alexander J Mogilner, Chris MacKnight, Kenneth Rockwood.   

Abstract

In a representative Canadian population survey (n=66589) the proportion of accumulated deficits in a frailty index showed a linear relationship with mortality in a log-log plot, such that the mortality rate was a power-law function of the frailty index. Represented in this way, the frailty index readily summarizes individual differences in health status. The exponent and amplitude parameters of the power function are gender specific, reflecting that while, on average, women accumulate more deficits than men of the same age, their risk of mortality is lower. The dependence of the mortality rate on the frailty index points to the merit of the index as a simple and accessible tool for estimating individual risks of mortality.

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Mesh:

Year:  2002        PMID: 12425952     DOI: 10.1016/s0047-6374(02)00082-9

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN: 0047-6374            Impact factor:   5.432


  61 in total

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4.  Biological Aging and the Human Gut Microbiota.

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5.  Association of healthy aging with parental longevity.

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6.  Change in frailty and risk of death in older persons.

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Journal:  Exp Aging Res       Date:  2009 Jan-Mar       Impact factor: 1.645

7.  The impact of frailty on pharmacokinetics in older people: using gentamicin population pharmacokinetic modeling to investigate changes in renal drug clearance by glomerular filtration.

Authors:  Claire Johnston; Sarah N Hilmer; Andrew J McLachlan; Slade T Matthews; Peter R Carroll; Carl M Kirkpatrick
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Review 8.  Frailty: Identifying elderly patients at high risk of poor outcomes.

Authors:  Linda Lee; George Heckman; Frank J Molnar
Journal:  Can Fam Physician       Date:  2015-03       Impact factor: 3.275

9.  Survival after non-resection of colorectal cancer: the argument for including non-operatives in consultant outcome reporting in the UK.

Authors:  M Abdel-Halim; H Wu; M Poustie; A Beveridge; N Scott; P J Mitchell
Journal:  Ann R Coll Surg Engl       Date:  2018-10-24       Impact factor: 1.891

10.  Frailty is associated with longer hospital stay and increased mortality in hospitalized older patients.

Authors:  D Khandelwal; A Goel; U Kumar; V Gulati; R Narang; A B Dey
Journal:  J Nutr Health Aging       Date:  2012-08       Impact factor: 4.075

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