Literature DB >> 23076064

A biocatalyst inspired by cancer.

Lenny Dang.   

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Year:  2012        PMID： 23076064     DOI： 10.1038/nchembio.1090

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  8 in total

Review 1.  Enzyme promiscuity: a mechanistic and evolutionary perspective.

Authors:  Olga Khersonsky; Dan S Tawfik
Journal:  Annu Rev Biochem       Date:  2010       Impact factor: 23.643

Review 2.  Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target.

Authors:  Changcun Guo; Christopher J Pirozzi; Giselle Y Lopez; Hai Yan
Journal:  Curr Opin Neurol       Date:  2011-12       Impact factor: 5.710

3.  Network context and selection in the evolution to enzyme specificity.

Authors:  Hojung Nam; Nathan E Lewis; Joshua A Lerman; Dae-Hee Lee; Roger L Chang; Donghyuk Kim; Bernhard O Palsson
Journal:  Science       Date:  2012-08-31       Impact factor: 47.728

4.  Induced fit and the catalytic mechanism of isocitrate dehydrogenase.

Authors:  Susana Gonçalves; Stephen P Miller; Maria A Carrondo; Anthony M Dean; Pedro M Matias
Journal:  Biochemistry       Date:  2012-08-27       Impact factor: 3.162

5.  Directed evolution of hydrolases for prevention of G-type nerve agent intoxication.

Authors:  Rinkoo D Gupta; Moshe Goldsmith; Yacov Ashani; Yair Simo; Gavriel Mullokandov; Hagit Bar; Moshe Ben-David; Haim Leader; Raanan Margalit; Israel Silman; Joel L Sussman; Dan S Tawfik
Journal:  Nat Chem Biol       Date:  2011-01-09       Impact factor: 15.040

6.  Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Authors:  Lenny Dang; David W White; Stefan Gross; Bryson D Bennett; Mark A Bittinger; Edward M Driggers; Valeria R Fantin; Hyun Gyung Jang; Shengfang Jin; Marie C Keenan; Kevin M Marks; Robert M Prins; Patrick S Ward; Katharine E Yen; Linda M Liau; Joshua D Rabinowitz; Lewis C Cantley; Craig B Thompson; Matthew G Vander Heiden; Shinsan M Su
Journal:  Nature       Date:  2009-12-10       Impact factor: 49.962

Review 7.  Directed enzyme evolution: climbing fitness peaks one amino acid at a time.

Authors:  Cara A Tracewell; Frances H Arnold
Journal:  Curr Opin Chem Biol       Date:  2009-02-25       Impact factor: 8.822

8.  Enzyme redesign guided by cancer-derived IDH1 mutations.

Authors:  Zachary J Reitman; Bryan D Choi; Ivan Spasojevic; Darell D Bigner; John H Sampson; Hai Yan
Journal:  Nat Chem Biol       Date:  2012-09-23       Impact factor: 15.040
  8 in total

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