Literature DB >> 23061092

Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells.

Michael D Scott1, Rinku Dutta, Manas K Haldar, Anil Wagh, Thomas R Gustad, Benedict Law, Daniel L Friesner, Sanku Mallik.   

Abstract

Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level possibly due to their ability to interact with extracellular enzymes that are over-expressed in cancerous conditions.

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Year:  2012        PMID: 23061092      PMCID: PMC3490703          DOI: 10.1039/c2an35877h

Source DB:  PubMed          Journal:  Analyst        ISSN: 0003-2654            Impact factor:   4.616


  14 in total

1.  Synthesis of barbiturate-based methionine aminopeptidase-1 inhibitors.

Authors:  Manas K Haldar; Michael D Scott; Nitesh Sule; D K Srivastava; Sanku Mallik
Journal:  Bioorg Med Chem Lett       Date:  2008-03-04       Impact factor: 2.823

2.  Fluorescent bio-barcode DNA assay for the detection of Salmonella enterica serovar Enteritidis.

Authors:  Deng Zhang; David J Carr; Evangelyn C Alocilja
Journal:  Biosens Bioelectron       Date:  2008-08-19       Impact factor: 10.618

3.  Next-generation DNA sequencing.

Authors:  Jay Shendure; Hanlee Ji
Journal:  Nat Biotechnol       Date:  2008-10       Impact factor: 54.908

Review 4.  Regulating the regulators: posttranslational modifications of RNA silencing factors.

Authors:  Inha Heo; V Narry Kim
Journal:  Cell       Date:  2009-10-02       Impact factor: 41.582

5.  Fluorescent water soluble polymers for isozyme-selective interactions with matrix metalloproteinase-9.

Authors:  Rinku Dutta; Michael D Scott; Manas K Haldar; Bratati Ganguly; D K Srivastava; Daniel L Friesner; Sanku Mallik
Journal:  Bioorg Med Chem Lett       Date:  2011-02-28       Impact factor: 2.823

6.  Histone deacetylases 1, 6 and 8 are critical for invasion in breast cancer.

Authors:  Soon Young Park; Ji Ae Jun; Kang Jin Jeong; Hoi Jeong Heo; Jang Sihn Sohn; Hoi Young Lee; Chang Gyo Park; Jaeku Kang
Journal:  Oncol Rep       Date:  2011-03-28       Impact factor: 3.906

Review 7.  Aromatic rings in chemical and biological recognition: energetics and structures.

Authors:  Laura M Salonen; Manuel Ellermann; François Diederich
Journal:  Angew Chem Int Ed Engl       Date:  2011-04-28       Impact factor: 15.336

8.  Lysine acetylation targets protein complexes and co-regulates major cellular functions.

Authors:  Chunaram Choudhary; Chanchal Kumar; Florian Gnad; Michael L Nielsen; Michael Rehman; Tobias C Walther; Jesper V Olsen; Matthias Mann
Journal:  Science       Date:  2009-07-16       Impact factor: 47.728

9.  Patterns of MMP-2 and MMP-9 expression in human cancer cell lines.

Authors:  M W Roomi; J C Monterrey; T Kalinovsky; M Rath; A Niedzwiecki
Journal:  Oncol Rep       Date:  2009-05       Impact factor: 3.906

Review 10.  Systematic review: gene expression profiling assays in early-stage breast cancer.

Authors:  Luigi Marchionni; Renee F Wilson; Antonio C Wolff; Spyridon Marinopoulos; Giovanni Parmigiani; Eric B Bass; Steven N Goodman
Journal:  Ann Intern Med       Date:  2008-02-04       Impact factor: 25.391

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