| Literature DB >> 21367603 |
Rinku Dutta1, Michael D Scott, Manas K Haldar, Bratati Ganguly, D K Srivastava, Daniel L Friesner, Sanku Mallik.
Abstract
Matrix metalloproteinases (MMPs) are overexpressed in various pathological conditions, including cancers. Although these isozymes have similar active sites, the patterns of exposed amino acids on their surfaces are different. Herein, we report the synthesis and molecular interactions of two water soluble, fluorescent polymers which demonstrate selective interactions with MMP-9 compared to MMP-7 and -10.Entities:
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Year: 2011 PMID： 21367603 PMCID： PMC3063395 DOI： 10.1016/j.bmcl.2011.02.020
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823