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Literature DB >> 23044804

In vitro generation of platelets through direct conversion: first report in My Knowledge (iMK).

Shigeo Masuda¹, Mo Li, Juan Carlos Izpisua Belmonte.

Abstract

Blood transfusion medicine requires a constant supply of platelets, which is now totally donor dependent. Recent advances in the generation of platelets in vitro through megakaryocytes (MKs) may provide protocols not only via pluripotent stem cells, including induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs), but also via induced MKs (iMKs). For the first time, mouse and human fibroblasts are successfully transdifferentiated into iMKs by the introduction of three factors, p45NF-E2, Maf G, and Maf K.

Entities: Gene Species

Mesh：

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Year: 2012 PMID： 23044804 PMCID： PMC3567822 DOI： 10.1038/cr.2012.142

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

14 in total

Review 1. Platelet transfusions.

Authors: David F Stroncek; Paolo Rebulla
Journal: Lancet Date: 2007-08-04 Impact factor: 79.321

2. A more efficient method to generate integration-free human iPS cells.

Authors: Keisuke Okita; Yasuko Matsumura; Yoshiko Sato; Aki Okada; Asuka Morizane; Satoshi Okamoto; Hyenjong Hong; Masato Nakagawa; Koji Tanabe; Ken-ichi Tezuka; Toshiyuki Shibata; Takahiro Kunisada; Masayo Takahashi; Jun Takahashi; Hiroh Saji; Shinya Yamanaka
Journal: Nat Methods Date: 2011-04-03 Impact factor: 28.547

3. Stem-cell pioneer banks on future therapies.

Authors: David Cyranoski
Journal: Nature Date: 2012-08-09 Impact factor: 49.962

4. Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.

Authors: Masatoshi Kajiwara; Takashi Aoi; Keisuke Okita; Ryosuke Takahashi; Haruhisa Inoue; Naoya Takayama; Hiroshi Endo; Koji Eto; Junya Toguchida; Shinji Uemoto; Shinya Yamanaka
Journal: Proc Natl Acad Sci U S A Date: 2012-07-16 Impact factor: 11.205

5. Therapeutic platelet transfusion versus routine prophylactic transfusion in patients with haematological malignancies: an open-label, multicentre, randomised study.

Authors: Hannes Wandt; Kerstin Schaefer-Eckart; Knut Wendelin; Bettina Pilz; Martin Wilhelm; Markus Thalheimer; Ulrich Mahlknecht; Anthony Ho; Markus Schaich; Michael Kramer; Martin Kaufmann; Lothar Leimer; Rainer Schwerdtfeger; Roland Conradi; Gottfried Dölken; Anne Klenner; Mathias Hänel; Regina Herbst; Christian Junghanss; Gerhard Ehninger
Journal: Lancet Date: 2012-08-08 Impact factor: 79.321

6. Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors.

Authors: Naoya Takayama; Hidekazu Nishikii; Joichi Usui; Hiroko Tsukui; Akira Sawaguchi; Takashi Hiroyama; Koji Eto; Hiromitsu Nakauchi
Journal: Blood Date: 2008-04-03 Impact factor: 22.113

7. Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins.

Authors: K Igarashi; K Kataoka; K Itoh; N Hayashi; M Nishizawa; M Yamamoto
Journal: Nature Date: 1994-02-10 Impact factor: 49.962

8. Generating an iPSC bank for HLA-matched tissue transplantation based on known donor and recipient HLA types.

Authors: Craig J Taylor; Sarah Peacock; Afzal N Chaudhry; J Andrew Bradley; Eleanor M Bolton
Journal: Cell Stem Cell Date: 2012-08-03 Impact factor: 24.633

9. Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf.

Authors: Yukako Ono; Yuhuan Wang; Hidenori Suzuki; Shinichiro Okamoto; Yasuo Ikeda; Mitsuru Murata; Mortimer Poncz; Yumiko Matsubara
Journal: Blood Date: 2012-07-31 Impact factor: 22.113

10. Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells.

Authors: Naoya Takayama; Satoshi Nishimura; Sou Nakamura; Takafumi Shimizu; Ryoko Ohnishi; Hiroshi Endo; Tomoyuki Yamaguchi; Makoto Otsu; Ken Nishimura; Mahito Nakanishi; Akira Sawaguchi; Ryozo Nagai; Kazutoshi Takahashi; Shinya Yamanaka; Hiromitsu Nakauchi; Koji Eto
Journal: J Exp Med Date: 2010-11-22 Impact factor: 14.307

6 in total

1. Platelet bioreactor-on-a-chip.

Authors: Jonathan N Thon; Linas Mazutis; Stephen Wu; Joanna L Sylman; Allen Ehrlicher; Kellie R Machlus; Qiang Feng; Shijiang Lu; Robert Lanza; Keith B Neeves; David A Weitz; Joseph E Italiano
Journal: Blood Date: 2014-09-18 Impact factor: 22.113

Review 2. The Opportunities and Challenges regarding Induced Platelets from Human Pluripotent Stem Cells.

Authors: Meng-Xue Xu; Li-Ping Liu; Yu-Mei Li; Yun-Wen Zheng
Journal: Stem Cells Int Date: 2021-05-01 Impact factor: 5.443

Review 3. Manufacturing blood ex vivo: a futuristic approach to deal with the supply and safety concerns.

Authors: Vimal K Singh; Abhishek Saini; Kohichiro Tsuji; P B Sharma; Ramesh Chandra
Journal: Front Cell Dev Biol Date: 2014-06-11

Review 4. Platelet generation in vivo and in vitro.

Authors: Biao Wang; Jiansheng Zheng
Journal: Springerplus Date: 2016-06-21

5. Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis.

Authors: Ayse Kizilyer; Meera V Singh; Vir B Singh; Sumanun Suwunnakorn; James Palis; Sanjay B Maggirwar
Journal: Sci Rep Date: 2019-02-26 Impact factor: 4.379

Review 6. Generation of HLA Universal Megakaryocytes and Platelets by Genetic Engineering.

Authors: Constanca Figueiredo; Rainer Blasczyk
Journal: Front Immunol Date: 2021-10-27 Impact factor: 7.561

6 in total