Literature DB >> 23040900

The neural effects of psychotropic medications in children and adolescents.

Manpreet K Singh1, Kiki D Chang.   

Abstract

Little is known about the neurobiological effects of psychotropic medications used in the treatment of children and adolescents diagnosed with a psychiatric disorder. This review provides a synopsis of the literature demonstrating the neural effects associated with exposure to psychotropic medication in youth using multimodal neuroimaging. The article concludes by illustrating how, taken together, these studies suggest that pharmacological interventions during childhood do indeed affect brain structure and function in a detectable manner, and the effects appear to be ameliorative.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 23040900      PMCID： PMC3590023          DOI： 10.1016/j.chc.2012.07.010

Source DB:  PubMed          Journal:  Child Adolesc Psychiatr Clin N Am        ISSN： 1056-4993


  78 in total

1.  Practice parameter for the assessment and treatment of children and adolescents with bipolar disorder.

Authors:  Jon McClellan; Robert Kowatch; Robert L Findling
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2007-01       Impact factor: 8.829

2.  Enhanced prefrontal function with pharmacotherapy on a response inhibition task in adolescent bipolar disorder.

Authors:  Mani N Pavuluri; Alessandra M Passarotti; Erin M Harral; John A Sweeney
Journal:  J Clin Psychiatry       Date:  2010-08-24       Impact factor: 4.384

3.  Lithium treatment effects on Myo-inositol in adolescents with bipolar depression.

Authors:  Nick C Patel; Melissa P DelBello; Kim M Cecil; Caleb M Adler; Holly S Bryan; Kevin E Stanford; Stephen M Strakowski
Journal:  Biol Psychiatry       Date:  2006-11-01       Impact factor: 13.382

4.  Childhood-onset schizophrenia: brain MRI rescan after 2 years of clozapine maintenance treatment.

Authors:  J A Frazier; J N Giedd; D Kaysen; K Albus; S Hamburger; J Alaghband-Rad; M C Lenane; K McKenna; A Breier; J L Rapoport
Journal:  Am J Psychiatry       Date:  1996-04       Impact factor: 18.112

Review 5.  Toward dysfunctional connectivity: a review of neuroimaging findings in pediatric major depressive disorder.

Authors:  Leslie A Hulvershorn; Kathryn Cullen; Amit Anand
Journal:  Brain Imaging Behav       Date:  2011-12       Impact factor: 3.978

6.  Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder.

Authors:  P Davanzo; M A Thomas; K Yue; T Oshiro; T Belin; M Strober; J McCracken
Journal:  Neuropsychopharmacology       Date:  2001-04       Impact factor: 7.853

7.  Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?

Authors:  G J Moore; J M Bebchuk; K Hasanat; G Chen; N Seraji-Bozorgzad; I B Wilds; M W Faulk; S Koch; D A Glitz; L Jolkovsky; H K Manji
Journal:  Biol Psychiatry       Date:  2000-07-01       Impact factor: 13.382

8.  Effect of divalproex on brain morphometry, chemistry, and function in youth at high-risk for bipolar disorder: a pilot study.

Authors:  Kiki Chang; Asya Karchemskiy; Ryan Kelley; Meghan Howe; Amy Garrett; Nancy Adleman; Allan Reiss
Journal:  J Child Adolesc Psychopharmacol       Date:  2009-02       Impact factor: 2.576

9.  Limbic and corpus callosum aberrations in adolescents with bipolar disorder: a tract-based spatial statistics analysis.

Authors:  Naama Barnea-Goraly; Kiki D Chang; Asya Karchemskiy; Meghan E Howe; Allan L Reiss
Journal:  Biol Psychiatry       Date:  2009-04-22       Impact factor: 13.382

10.  Glutamine and glutamate levels in children and adolescents with bipolar disorder: a 4.0-T proton magnetic resonance spectroscopy study of the anterior cingulate cortex.

Authors:  Constance M Moore; Jean A Frazier; Carol A Glod; Janis L Breeze; Megan Dieterich; Chelsea T Finn; Blaise deB Frederick; Perry F Renshaw
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2007-04       Impact factor: 8.829
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  13 in total

1.  Abnormal deactivation of the inferior frontal gyrus during implicit emotion processing in youth with bipolar disorder: attenuated by medication.

Authors:  Danella M Hafeman; Genna Bebko; Michele A Bertocci; Jay C Fournier; Lisa Bonar; Susan B Perlman; Michael Travis; Mary Kay Gill; Vaibhav A Diwadkar; Jeffrey L Sunshine; Scott K Holland; Robert A Kowatch; Boris Birmaher; David Axelson; Sarah M Horwitz; L Eugene Arnold; Mary A Fristad; Thomas W Frazier; Eric A Youngstrom; Robert L Findling; Wayne Drevets; Mary L Phillips
Journal:  J Psychiatr Res       Date:  2014-08-08       Impact factor: 4.791

2.  Atypical cortical gyrification in adolescents with histories of heavy prenatal alcohol exposure.

Authors:  M Alejandra Infante; Eileen M Moore; Amanda Bischoff-Grethe; Robyn Migliorini; Sarah N Mattson; Edward P Riley
Journal:  Brain Res       Date:  2015-08-12       Impact factor: 3.252

3.  Psychotropic Medications and Their Effect on Brain Volumes in Childhood Psychopathology.

Authors:  Natasha Marrus; Marisa Bell; Joan L Luby
Journal:  Child Adolesc Psychopharmacol News       Date:  2014-04

Review 4.  Dosing and Monitoring: Children and Adolescents.

Authors:  Glenn S Hirsch
Journal:  Psychopharmacol Bull       Date:  2018-02-05

5.  Hyperactivation in Cognitive Control and Visual Attention Brain Regions During Emotional Interference in Adolescent Depression.

Authors:  Natalie L Colich; Tiffany C Ho; Lara C Foland-Ross; Caitlin Eggleston; Sarah J Ordaz; Manpreet K Singh; Ian H Gotlib
Journal:  Biol Psychiatry Cogn Neurosci Neuroimaging       Date:  2017-07

6.  White matter disruptions in patients with bipolar disorder.

Authors:  Lucija Abramovic; Marco P M Boks; Annabel Vreeker; Sanne Verkooijen; Annet H van Bergen; Roel A Ophoff; René S Kahn; Neeltje E M van Haren
Journal:  Eur Neuropsychopharmacol       Date:  2018-05-18       Impact factor: 4.600

7.  Long-term impacts of adolescent risperidone treatment on behavioral responsiveness to olanzapine and clozapine in adulthood.

Authors:  Jing Qiao; Qinglin Zhang; Ming Li
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2013-10-16       Impact factor: 5.067

8.  Treatment of psychiatric symptoms among offspring of parents with bipolar disorder.

Authors:  Isheeta Zalpuri; Manpreet K Singh
Journal:  Curr Treat Options Psychiatry       Date:  2017-11-04

Review 9.  Updated report on tools to measure outcomes of clinical trials in fragile X syndrome.

Authors:  Dejan B Budimirovic; Elizabeth Berry-Kravis; Craig A Erickson; Scott S Hall; David Hessl; Allan L Reiss; Margaret K King; Leonard Abbeduto; Walter E Kaufmann
Journal:  J Neurodev Disord       Date:  2017-06-12       Impact factor: 4.025

10.  Psychotropic medication use in autism spectrum disorders may affect functional brain connectivity.

Authors:  Annika C Linke; Lindsay Olson; Yangfeifei Gao; Inna Fishman; Ralph-Axel Müller
Journal:  Biol Psychiatry Cogn Neurosci Neuroimaging       Date:  2017-09
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