OBJECTIVE: To examine the association between maternal racial origin and a wide range of adverse pregnancy outcomes after adjustment for confounding factors in obstetric history and maternal characteristics. METHODS: This was a retrospective study in women with singleton pregnancies attending their first routine hospital visit at 11 + 0 to 13 + 6 weeks of gestation. Data on maternal characteristics, and medical and obstetric history were collected and pregnancy outcomes ascertained. Regression analysis was performed to examine the association between racial origin and adverse pregnancy outcomes including pre-eclampsia (PE), gestational hypertension (GH), gestational diabetes mellitus (GDM), preterm delivery (PTD), small-for-gestational age (SGA), large-for-gestational age (LGA), miscarriage, stillbirth and elective and emergency Cesarean section (CS). RESULTS: The study population included 76 158 singleton pregnancies with a live fetus at 11 + 0 to 13 + 6 weeks. In addition to maternal characteristics and obstetric history, Afro-Caribbean racial origin was associated with increased risk for miscarriage, stillbirth, PE, GH, spontaneous PTD, GDM, SGA and CS. In women of South Asian racial origin there was increased risk for PE, GDM, SGA and CS, and East Asian race contributed to the prediction of GDM and SGA. CONCLUSION: Maternal racial origin should be combined with other maternal characteristics and obstetric history when calculating an individualized adjusted risk for adverse pregnancy outcome.
OBJECTIVE: To examine the association between maternal racial origin and a wide range of adverse pregnancy outcomes after adjustment for confounding factors in obstetric history and maternal characteristics. METHODS: This was a retrospective study in women with singleton pregnancies attending their first routine hospital visit at 11 + 0 to 13 + 6 weeks of gestation. Data on maternal characteristics, and medical and obstetric history were collected and pregnancy outcomes ascertained. Regression analysis was performed to examine the association between racial origin and adverse pregnancy outcomes including pre-eclampsia (PE), gestational hypertension (GH), gestational diabetes mellitus (GDM), preterm delivery (PTD), small-for-gestational age (SGA), large-for-gestational age (LGA), miscarriage, stillbirth and elective and emergency Cesarean section (CS). RESULTS: The study population included 76 158 singleton pregnancies with a live fetus at 11 + 0 to 13 + 6 weeks. In addition to maternal characteristics and obstetric history, Afro-Caribbean racial origin was associated with increased risk for miscarriage, stillbirth, PE, GH, spontaneous PTD, GDM, SGA and CS. In women of South Asian racial origin there was increased risk for PE, GDM, SGA and CS, and East Asian race contributed to the prediction of GDM and SGA. CONCLUSION: Maternal racial origin should be combined with other maternal characteristics and obstetric history when calculating an individualized adjusted risk for adverse pregnancy outcome.
Authors: Liona C Poon; Andrew Shennan; Jonathan A Hyett; Anil Kapur; Eran Hadar; Hema Divakar; Fionnuala McAuliffe; Fabricio da Silva Costa; Peter von Dadelszen; Harold David McIntyre; Anne B Kihara; Gian Carlo Di Renzo; Roberto Romero; Mary D'Alton; Vincenzo Berghella; Kypros H Nicolaides; Moshe Hod Journal: Int J Gynaecol Obstet Date: 2019-05 Impact factor: 3.561
Authors: Jagteshwar Grewal; Katherine L Grantz; Cuilin Zhang; Anthony Sciscione; Deborah A Wing; William A Grobman; Roger B Newman; Ronald Wapner; Mary E D'Alton; Daniel Skupski; Michael P Nageotte; Angela C Ranzini; John Owen; Edward K Chien; Sabrina Craigo; Paul S Albert; Sungduk Kim; Mary L Hediger; Germaine M Buck Louis Journal: Int J Epidemiol Date: 2018-02-01 Impact factor: 7.196
Authors: Germaine M Buck Louis; Jagteshwar Grewal; Paul S Albert; Anthony Sciscione; Deborah A Wing; William A Grobman; Roger B Newman; Ronald Wapner; Mary E D'Alton; Daniel Skupski; Michael P Nageotte; Angela C Ranzini; John Owen; Edward K Chien; Sabrina Craigo; Mary L Hediger; Sungduk Kim; Cuilin Zhang; Katherine L Grantz Journal: Am J Obstet Gynecol Date: 2015-10 Impact factor: 8.661
Authors: Helen D Bailey; Akilew A Adane; Brad M Farrant; Scott W White; Pia Hardelid; Carrington C J Shepherd Journal: Arch Gynecol Obstet Date: 2020-04-21 Impact factor: 2.344