Literature DB >> 23011954

An advance in the chemical synthesis of homogeneous N-linked glycopolypeptides by convergent aspartylation.

Ping Wang1, Baptiste Aussedat, Yusufbhai Vohra, Samuel J Danishefsky.   

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Year:  2012        PMID: 23011954      PMCID: PMC3500778          DOI: 10.1002/anie.201205038

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  29 in total

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2.  Total synthesis of the α-subunit of human glycoprotein hormones: toward fully synthetic homogeneous human follicle-stimulating hormone.

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4.  Fragment condensation of C-terminal pseudoproline peptides without racemization on the solid phase.

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5.  Convenient synthesis of a sialylglycopeptide-thioester having an intact and homogeneous complex-type disialyl-oligosaccharide.

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7.  Probing the stability of nonglycosylated wild-type erythropoietin protein via reiterative alanine ligations.

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8.  Application of Fmoc-amino acid carrying an unmasked carbohydrate to the synthesis of the epidermal growth factor-like domain of bovine blood coagulation factor IX.

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9.  Folding of aminosuccinyl peptides: thermodynamic data from temperature dependent circular dichroism measurements.

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10.  Chemical synthesis of a glycoprotein having an intact human complex-type sialyloligosaccharide under the Boc and Fmoc synthetic strategies.

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Review 5.  Structural Insights from HIV-Antibody Coevolution and Related Immunization Studies.

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6.  Total Chemical Synthesis of Human Thyroid-Stimulating Hormone (hTSH) β-Subunit: Application of Arginine-tagged Acetamidomethyl (AcmR) Protecting Groups.

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Review 7.  The winding pathway to erythropoietin along the chemistry-biology frontier: a success at last.

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8.  Synthesis of granulocyte-macrophage colony-stimulating factor as homogeneous glycoforms and early comparisons with yeast cell-derived material.

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9.  Chemical synthesis of the ATAD2 bromodomain.

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10.  Chemical synthesis of highly congested gp120 V1V2 N-glycopeptide antigens for potential HIV-1-directed vaccines.

Authors:  Baptiste Aussedat; Yusuf Vohra; Peter K Park; Alberto Fernández-Tejada; S Munir Alam; S Moses Dennison; Frederick H Jaeger; Kara Anasti; Shelley Stewart; Julie H Blinn; Hua-Xin Liao; Joseph G Sodroski; Barton F Haynes; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2013-08-22       Impact factor: 15.419

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