Literature DB >> 230106

Immunization against poliomyelitis: risk/benefit/cost in a changing context.

J Salk.   

Abstract

Benefit/risk factors in immunization against poliomyelitis are examined from the viewpoint of the relative risk and efficacy of killed and live poliovirus vaccines in the currently changing contexts of poliomyelitis prevalence in developed and developing countries. Risk factors include virus of vaccine origin gaining access to the CNS, and failure of the vaccine to immunize. Data are presented to illustrate the degree to which the respective risks occur in developed and developing countries. The ultimate elimination of risk by eradication of wild and vaccine virus from the population is discussed.

Entities:  

Keywords:  Americas; Cost Benefit Analysis; Cost Effectiveness; Delivery Of Health Care; Developed Countries; Developing Countries; Diseases; Evaluation; Evaluation Indexes; Evaluation Methodology; Health; Health Services; Immunization--cost; Medicine; North America; Northern America; Preventive Medicine; Primary Health Care; Quantitative Evaluation; Research Methodology; United States; Vaccination--administraction and dosage; Vaccination--cost; Viral Diseases--prevention and control

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Year:  1979        PMID: 230106

Source DB:  PubMed          Journal:  Dev Biol Stand        ISSN: 0301-5149


  2 in total

Review 1.  Regulating impact on bystanders in clinical trials: An unsettled frontier.

Authors:  Nir Eyal; Jonathan Kimmelman; Lisa G Holtzman; Marc Lipsitch
Journal:  Clin Trials       Date:  2019-08-01       Impact factor: 2.486

2.  Healthcare technology: physician collaboration in reducing the surgical cost.

Authors:  Steven A Olson; William T Obremskey; Kevin J Bozic
Journal:  Clin Orthop Relat Res       Date:  2013-06       Impact factor: 4.176

  2 in total

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