Literature DB >> 22999842

Accuracy and trust of self-testing for bacterial vaginosis.

Jill S Huppert1, Elizabeth A Hesse, Marianne Claire Bernard, Justin R Bates, Charlotte A Gaydos, Jessica A Kahn.   

Abstract

PURPOSE: Two point-of-care tests are available to detect bacterial vaginosis (BV), a common vaginal condition. This study aimed to (1) compare the accuracy of two self-performed BV tests with clinician-performed BV tests and with clinical diagnosis of BV; and (2) compare trust of results for self-performed BV testing with clinician-performed BV testing.
METHODS: Participants (14-22 years old) in a study assessing self-testing for Trichomonas vaginalis were also asked to perform a self-test for BV (using a pH or sialidase test). Results were compared with clinician-performed tests and with clinical diagnosis of BV (defined by modified Amsel criteria). A two-item subscale from a larger acceptability scale was used to assess trust at baseline, after testing, and after discussion of results.
RESULTS: All 131 women performed self-BV testing correctly. Agreement between self- and clinician-performed tests was good (κ: .5-.7) Compared with clinical diagnosis of BV, self-pH was 73% sensitive and 67% specific, and self-sialidase was 40% sensitive and 90% specific. Trust in self-performed BV testing was lower than trust in clinician-performed BV testing at baseline, but increased after testing and discussion of results.
CONCLUSIONS: Young women can perform self-tests for BV with reasonable accuracy, which could increase testing when pelvic examinations are not feasible. Trust in self-testing increased after experience and after discussion of test results. Although the pH test is available over the counter, young women may continue to rely on clinicians for testing.
Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

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Mesh:

Year:  2012        PMID: 22999842      PMCID: PMC3457017          DOI: 10.1016/j.jadohealth.2012.01.017

Source DB:  PubMed          Journal:  J Adolesc Health        ISSN: 1054-139X            Impact factor:   5.012


  28 in total

1.  Validity of the vaginal gram stain for the diagnosis of bacterial vaginosis.

Authors:  J R Schwebke; S L Hillier; J D Sobel; J A McGregor; R L Sweet
Journal:  Obstet Gynecol       Date:  1996-10       Impact factor: 7.661

2.  Bias in discrepant analysis: when two wrongs don't make a right.

Authors:  W C Miller
Journal:  J Clin Epidemiol       Date:  1998-03       Impact factor: 6.437

3.  Bacterial vaginosis and trichomoniasis vaginitis are risk factors for cuff cellulitis after abdominal hysterectomy.

Authors:  D E Soper; R C Bump; W G Hurt
Journal:  Am J Obstet Gynecol       Date:  1990-09       Impact factor: 8.661

4.  A cluster analysis of bacterial vaginosis-associated microflora and pelvic inflammatory disease.

Authors:  Roberta B Ness; Kevin E Kip; Sharon L Hillier; David E Soper; Carol A Stamm; Richard L Sweet; Peter Rice; Holly E Richter
Journal:  Am J Epidemiol       Date:  2005-08-10       Impact factor: 4.897

5.  Bacterial vaginosis and susceptibility to HIV infection in South African women: a nested case-control study.

Authors:  Landon Myer; Lynette Denny; Robin Telerant; Michelle de Souza; Thomas C Wright; Louise Kuhn
Journal:  J Infect Dis       Date:  2005-09-09       Impact factor: 5.226

6.  Evaluation of clinical methods for diagnosing bacterial vaginosis.

Authors:  Robert E Gutman; Jeffrey F Peipert; Sherry Weitzen; Jeffrey Blume
Journal:  Obstet Gynecol       Date:  2005-03       Impact factor: 7.661

7.  Home STI testing: the adolescent female's opinion.

Authors:  Kathleen P Tebb; Maarit H Paukku; Meaghan R Pai-Dhungat; Afua-Adoma Gyamfi; Mary-Ann B Shafer
Journal:  J Adolesc Health       Date:  2004-12       Impact factor: 5.012

8.  Evaluation of a point-of-care test, BVBlue, and clinical and laboratory criteria for diagnosis of bacterial vaginosis.

Authors:  C S Bradshaw; A N Morton; S M Garland; L B Horvath; I Kuzevska; C K Fairley
Journal:  J Clin Microbiol       Date:  2005-03       Impact factor: 5.948

9.  Bacterial vaginosis in virginal and sexually active adolescent females: evidence against exclusive sexual transmission.

Authors:  R C Bump; W J Buesching
Journal:  Am J Obstet Gynecol       Date:  1988-04       Impact factor: 8.661

10.  Evaluation of vaginal infections in adolescent women: can it be done without a speculum?

Authors:  D R Blake; A Duggan; T Quinn; J Zenilman; A Joffe
Journal:  Pediatrics       Date:  1998-10       Impact factor: 7.124

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  10 in total

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2.  Microbiological findings in prepubertal and pubertal girls with vulvovaginitis.

Authors:  Stavroula Baka; Stiliani Demeridou; George Kaparos; Konstantinos Tsoutsouras; Sotirios Touloumakos; Maria Dagre; Sofia Meretaki; Anthia Chasiakou; Vasiliki Koumaki; Athanasios Tsakris
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3.  Clinical evidence for the role of Trichomonas vaginalis in regulation of secretory leukocyte protease inhibitor in the female genital tract.

Authors:  Jill S Huppert; Bin Huang; Chen Chen; Hassan Y Dawood; Raina N Fichorova
Journal:  J Infect Dis       Date:  2013-01-25       Impact factor: 5.226

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Review 5.  Obtaining self-samples to diagnose curable sexually transmitted infections: a systematic review of patients' experiences.

Authors:  Priyamvada Paudyal; Carrie Llewellyn; Jason Lau; Mohammad Mahmud; Helen Smith
Journal:  PLoS One       Date:  2015-04-24       Impact factor: 3.240

6.  The presence of the putative Gardnerella vaginalis sialidase A gene in vaginal specimens is associated with bacterial vaginosis biofilm.

Authors:  Liselotte Hardy; Vicky Jespers; Magelien Van den Bulck; Jozefien Buyze; Lambert Mwambarangwe; Viateur Musengamana; Mario Vaneechoutte; Tania Crucitti
Journal:  PLoS One       Date:  2017-02-27       Impact factor: 3.240

7.  A Comparison of Colorimetric Assessment of Vaginal pH with Nugent Score for the Detection of Bacterial Vaginosis.

Authors:  Matthew K Hoffman; Mrutyunjaya B Bellad; Umesh S Charantimath; Avinash Kavi; Jyoti M Nagmoti; Mahantesh B Nagmoti; Ashalata A Mallapur; Geetanjali M Katageri; Umesh Y Ramadurg; Sheshidhar G Bannale; Amit P Revankar; M S Ganachari; Richard J Derman; Shivaprasad S Goudar
Journal:  Infect Dis Obstet Gynecol       Date:  2017-02-15

8.  Evaluation of reliability of self-collected vaginal swabs over physician-collected samples for diagnosis of bacterial vaginosis, candidiasis and trichomoniasis, in a resource-limited setting: a cross-sectional study in India.

Authors:  Zarine Khan; Aradhana Bhargava; Pratima Mittal; Rekha Bharti; Poonam Puri; Niti Khunger; Manju Bala
Journal:  BMJ Open       Date:  2019-08-27       Impact factor: 2.692

9.  Direct-to-Consumer Sexually Transmitted Infection Testing Services: A Position Statement from the American Sexually Transmitted Diseases Association.

Authors:  Cara Exten; Casey N Pinto; Anne M Gaynor; Beth Meyerson; Stacey B Griner; Barbara Van Der Pol
Journal:  Sex Transm Dis       Date:  2021-11-01       Impact factor: 3.868

10.  Antimicrobial Activity of a Vaginal Gel Formulation: Considerations Related to Vaginal Infection and Dysbiosis.

Authors:  Francesco De Seta; Bryan Larsen
Journal:  Pathogens       Date:  2021-12-03
  10 in total

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