Literature DB >> 22999273

iPSC technology to study human aging and aging-related disorders.

Guang-Hui Liu1, Zhichao Ding, Juan Carlos Izpisua Belmonte.   

Abstract

A global aging population, normally accompanied by a high incidence of aging-associated diseases, has prompted a renewed interest in basic research on human aging. Although encouraging progress has been achieved using animal models, the underlying fundamental mechanisms of aging remain largely unknown. Here, we review the human induced pluripotent stem cell (hiPSC)-based models of aging and aging-related diseases. These models seek to advance our knowledge of aging molecular mechanisms and help to develop strategies for treating aging-associated human diseases.
Copyright © 2012 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Year:  2012        PMID： 22999273     DOI： 10.1016/j.ceb.2012.08.014

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  28 in total

Review 1.  Alzheimer's in 3D culture: challenges and perspectives.

Authors:  Carla D'Avanzo; Jenna Aronson; Young Hye Kim; Se Hoon Choi; Rudolph E Tanzi; Doo Yeon Kim
Journal:  Bioessays       Date:  2015-08-07       Impact factor: 4.345

2.  DNA methylome: Unveiling your biological age.

Authors:  Ming Li; Wensu Liu; Tingting Yuan; Ruijun Bai; Guang-Hui Liu; Weizhou Zhang; Jing Qu
Journal:  Protein Cell       Date:  2013-10       Impact factor: 14.870

3.  Application of induced pluripotent stem cells to model smooth muscle cell function in vascular diseases.

Authors:  HaYeun Ji; Hye Sung Kim; Hae-Won Kim; Kam W Leong
Journal:  Curr Opin Biomed Eng       Date:  2017-03-22

4.  Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.

Authors:  Weiqi Zhang; Jingyi Li; Keiichiro Suzuki; Jing Qu; Ping Wang; Junzhi Zhou; Xiaomeng Liu; Ruotong Ren; Xiuling Xu; Alejandro Ocampo; Tingting Yuan; Jiping Yang; Ying Li; Liang Shi; Dee Guan; Huize Pan; Shunlei Duan; Zhichao Ding; Mo Li; Fei Yi; Ruijun Bai; Yayu Wang; Chang Chen; Fuquan Yang; Xiaoyu Li; Zimei Wang; Emi Aizawa; April Goebl; Rupa Devi Soligalla; Pradeep Reddy; Concepcion Rodriguez Esteban; Fuchou Tang; Guang-Hui Liu; Juan Carlos Izpisua Belmonte
Journal:  Science       Date:  2015-04-30       Impact factor: 47.728

Review 5.  Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency.

Authors:  Lorenz Studer; Elsa Vera; Daniela Cornacchia
Journal:  Cell Stem Cell       Date:  2015-06-04       Impact factor: 24.633

Review 6.  Induced pluripotent stem cells from ALS patients for disease modeling.

Authors:  Jean-Philippe Richard; Nicholas J Maragakis
Journal:  Brain Res       Date:  2014-09-16       Impact factor: 3.252

Review 7.  Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells.

Authors:  Priya Srikanth; Tracy L Young-Pearse
Journal:  J Neurogenet       Date:  2014-03-17       Impact factor: 1.250

Review 8.  Epigenetics of aging and aging-related disease.

Authors:  Anne Brunet; Shelley L Berger
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-06       Impact factor: 6.053

Review 9.  The Emergence of Geroscience as an Interdisciplinary Approach to the Enhancement of Health Span and Life Span.

Authors:  Felipe Sierra
Journal:  Cold Spring Harb Perspect Med       Date:  2016-04-01       Impact factor: 6.915

Review 10.  Back and forth in time: Directing age in iPSC-derived lineages.

Authors:  Daniela Cornacchia; Lorenz Studer
Journal:  Brain Res       Date:  2015-11-17       Impact factor: 3.252
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.