Literature DB >> 22961673

Acute kidney injury due to intravenous bleach injection.

Ashish Verma1, Vijay K Vanguri, Venkata Golla, Sean Rhyee, Matthew Trainor, Konstantin Abramov.   

Abstract

INTRODUCTION: Sodium hypochlorite is the active ingredient in bleach, a ubiquitous household disinfectant, and has known toxicities depending on route of exposure and amount. Acute kidney injury due to sodium hypochlorite exposure has never been reported. Patients that did develop nephrotoxicity following bleach exposure did so due to development of other risk factors for kidney injury such as volume depletion or sepsis. DISCUSSION: We report a patient who presented with black urine after parenteral self-administration of a large quantity of bleach. We review the clinical presentation, laboratory and biopsy findings, and outcome as well as discuss possible mechanisms of sodium hypochlorite toxicity and management strategies.

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Year:  2013        PMID: 22961673      PMCID: PMC3576498          DOI: 10.1007/s13181-012-0259-6

Source DB:  PubMed          Journal:  J Med Toxicol        ISSN: 1556-9039


  15 in total

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Review 5.  Toxicity and safety of topical sodium hypochlorite.

Authors:  Mary K Bruch
Journal:  Contrib Nephrol       Date:  2007       Impact factor: 1.580

6.  Acute kidney injury in a patient with melanuria, diffuse melanosis, and metastatic malignant melanoma.

Authors:  Thilo Gambichler; Markus Stücker; Katja Kerner; Stefan Weiner; Rüdiger Waldherr; Peter Altmeyer; Alexander Kreuter
Journal:  Am J Clin Dermatol       Date:  2008       Impact factor: 7.403

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Authors:  D L Morgan
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Review 9.  Bench-to-bedside review: Rhabdomyolysis -- an overview for clinicians.

Authors:  Ana L Huerta-Alardín; Joseph Varon; Paul E Marik
Journal:  Crit Care       Date:  2004-10-20       Impact factor: 9.097

10.  Spectrum of sodium hypochlorite toxicity in man-also a concern for nephrologists.

Authors:  Brandon Peck; Biruh Workeneh; Huseyin Kadikoy; Samir J Patel; Abdul Abdellatif
Journal:  NDT Plus       Date:  2011-04-07
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  5 in total

Review 1.  Anatomy of sodium hypochlorite accidents involving facial ecchymosis - a review.

Authors:  Wan-chun Zhu; Jacqueline Gyamfi; Li-na Niu; G John Schoeffel; Si-ying Liu; Filippo Santarcangelo; Sara Khan; Kelvin C-Y Tay; David H Pashley; Franklin R Tay
Journal:  J Dent       Date:  2013-08-28       Impact factor: 4.379

2.  Health effects of sodium hypochlorite: review of published case reports.

Authors:  Insung Chung; Hyeseung Ryu; Seong-Yong Yoon; Jea Chul Ha
Journal:  Environ Anal Health Toxicol       Date:  2022-03-30

3.  N-acetylcysteine infusion in preventing hepatotoxicity secondary to intravenous injection of household bleach.

Authors:  Anthony H Eidan; James Sira; Mark Bellamy
Journal:  J Intensive Care Soc       Date:  2015-03-18

4.  Chemical-induced sclerodermoid disease triggered by pressure washing bleach solution.

Authors:  Victoria M Madray; Jenny E Liles; Loretta S Davis
Journal:  JAAD Case Rep       Date:  2020-10-10

5.  Epidemiology of acute kidney injury in the intensive care unit.

Authors:  James Case; Supriya Khan; Raeesa Khalid; Akram Khan
Journal:  Crit Care Res Pract       Date:  2013-03-21
  5 in total

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