| Literature DB >> 22961673 |
Ashish Verma1, Vijay K Vanguri, Venkata Golla, Sean Rhyee, Matthew Trainor, Konstantin Abramov.
Abstract
INTRODUCTION: Sodium hypochlorite is the active ingredient in bleach, a ubiquitous household disinfectant, and has known toxicities depending on route of exposure and amount. Acute kidney injury due to sodium hypochlorite exposure has never been reported. Patients that did develop nephrotoxicity following bleach exposure did so due to development of other risk factors for kidney injury such as volume depletion or sepsis. DISCUSSION: We report a patient who presented with black urine after parenteral self-administration of a large quantity of bleach. We review the clinical presentation, laboratory and biopsy findings, and outcome as well as discuss possible mechanisms of sodium hypochlorite toxicity and management strategies.Entities:
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Year: 2013 PMID: 22961673 PMCID: PMC3576498 DOI: 10.1007/s13181-012-0259-6
Source DB: PubMed Journal: J Med Toxicol ISSN: 1556-9039