Literature DB >> 28979424

N-acetylcysteine infusion in preventing hepatotoxicity secondary to intravenous injection of household bleach.

Anthony H Eidan1, James Sira1, Mark Bellamy1.   

Abstract

We present a case of non-accidental injection of 40 ml of domestic bleach through a long-term central venous catheter (CVC) with subsequent AKI, and for the first time in the literature severe coagulopathy and acute liver injury. We detail the clinical course of events and our management plan which adds to the body of evidence for prognosis and treatment in these unusual cases.

Entities:  

Keywords:  N-acetylcysteine; coagulopathy; hepatotoxicity; household bleach; sodium hypochlorite

Year:  2015        PMID: 28979424      PMCID: PMC5606442          DOI: 10.1177/1751143715576287

Source DB:  PubMed          Journal:  J Intensive Care Soc        ISSN: 1751-1437


  12 in total

Review 1.  Antioxidant properties of N-acetylcysteine: their relevance in relation to chronic obstructive pulmonary disease.

Authors:  P N R Dekhuijzen
Journal:  Eur Respir J       Date:  2004-04       Impact factor: 16.671

2.  Simplified regional citrate anticoagulation using a calcium-containing replacement solution for continuous venovenous hemofiltration.

Authors:  Ling Zhang; Yujie Liao; Jin Xiang; Wei Qin; Xiaodong Wu; Yi Tang; Yingying Yang; Zhiwen Chen; Ping Fu
Journal:  J Artif Organs       Date:  2012-12-28       Impact factor: 1.731

3.  Venous thrombosis following intravenous injection of household bleach.

Authors:  S H Rahmani; S Ahmadi; S S Vahdati; H H Moghaddam
Journal:  Hum Exp Toxicol       Date:  2012-02-01       Impact factor: 2.903

4.  Acute kidney injury due to intravenous bleach injection.

Authors:  Ashish Verma; Vijay K Vanguri; Venkata Golla; Sean Rhyee; Matthew Trainor; Konstantin Abramov
Journal:  J Med Toxicol       Date:  2013-03

Review 5.  Household bleaches based on sodium hypochlorite: review of acute toxicology and poison control center experience.

Authors:  F Racioppi; P A Daskaleros; N Besbelli; A Borges; C Deraemaeker; S I Magalini; R Martinez Arrieta; C Pulce; M L Ruggerone; P Vlachos
Journal:  Food Chem Toxicol       Date:  1994-09       Impact factor: 6.023

6.  Accidental systemic exposure to sodium hypochlorite (Chlorox) during hemodialysis.

Authors:  R H Hoy
Journal:  Am J Hosp Pharm       Date:  1981-10

Review 7.  Accidental injection with sodium hypochlorite: report of a case.

Authors:  M V Motta; M A L Chaves-Mendonca; C G Stirton; H F Cardozo
Journal:  Int Endod J       Date:  2009-02       Impact factor: 5.264

8.  Sodium hypochlorite-induced acute kidney injury.

Authors:  Brandon W Peck; Biruh Workeneh; Huseyin Kadikoy; Abdul Abdellatif
Journal:  Saudi J Kidney Dis Transpl       Date:  2014-03

9.  Intravenous injection of household bleach.

Authors:  D L Morgan
Journal:  Ann Emerg Med       Date:  1992-11       Impact factor: 5.721

Review 10.  Management of paracetamol poisoning.

Authors:  Robin E Ferner; James W Dear; D Nicholas Bateman
Journal:  BMJ       Date:  2011-04-19
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