Literature DB >> 22945398

[Standards of microbiological diagnostics of spondylodiscitis].

B Lehner1, M Akbar, C Rehnitz, G W Omlor, U Dapunt, I Burckhardt.   

Abstract

In most cases spondylodiscitis is due to a monomicrobial infection caused by hematogenous dissemination of Staphylococcus aureus. There are, however, many other possible pathogens causing spondylodiscitis and the pathogen responsible can only be identified in approximately 50% of cases. This leads to delayed diagnosis and therapy and an increased morbidity and mortality rate. Failures in planning and performing material recovery are often the reason. As pathogen-specific antimicrobial treatment according to the results of susceptibility testing is the main component of interdisciplinary therapy, all available methods for identification of the pathogen, such as blood cultures, intraoperative and computed tomography (CT) guided biopsies of inflammatory fluids and tissues as well as molecular biological methods should be performed to optimize antimicrobial therapy.

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Year:  2012        PMID: 22945398     DOI: 10.1007/s00132-012-1914-y

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  19 in total

1.  Broad-range PCR as a supplement to culture for detection of bacterial pathogens in patients with a clinically diagnosed spinal infection.

Authors:  Kurt Fuursted; Magnus Arpi; Bent Erling Lindblad; Lisbeth Nørum Pedersen
Journal:  Scand J Infect Dis       Date:  2008

Review 2.  [Revision strategy for periprosthetic infection].

Authors:  B Lehner; D Witte; A J Suda; S Weiss
Journal:  Orthopade       Date:  2009-08       Impact factor: 1.087

3.  Metastatic infectious disease and clinical outcome in Staphylococcus aureus and Streptococcus species bacteremia.

Authors:  Fidel J Vos; Bart Jan Kullberg; Patrick D Sturm; Paul F M Krabbe; Arie P J van Dijk; Geert J A Wanten; Wim J G Oyen; Chantal P Bleeker-Rovers
Journal:  Medicine (Baltimore)       Date:  2012-03       Impact factor: 1.889

4.  [Pyogenic spondylodiscitis of the thoracic and lumbar spine : a new classification and guide for surgical decision-making].

Authors:  M Akbar; B Lehner; S Doustdar; C H Fürstenberg; S Hemmer; T Bruckner; C Carstens; B Wiedenhöfer
Journal:  Orthopade       Date:  2011-07       Impact factor: 1.087

5.  New needle biopsy technique for lumbar pyogenic spondylodiscitis.

Authors:  Motohide Shibayama; Masashizu Nagahara; Gou Kawase; Kazuyoshi Fujiwara; Youhei Kawaguchi; Jun Mizutani
Journal:  Spine (Phila Pa 1976)       Date:  2010-11-01       Impact factor: 3.468

6.  A seven-year prospective study on spondylodiscitis: epidemiological and microbiological features.

Authors:  C D'Agostino; L Scorzolini; A P Massetti; M Carnevalini; G d'Ettorre; M Venditti; V Vullo; G B Orsi
Journal:  Infection       Date:  2010-02-27       Impact factor: 3.553

7.  [Spondylodiscitis - an interdisciplinary challenge].

Authors:  K Zarghooni; M Röllinghoff; J Siewe; G Fätkenheuer; H Seifert; P Eysel; R Sobottke
Journal:  Dtsch Med Wochenschr       Date:  2010-05-31       Impact factor: 0.628

8.  Spontaneous pyogenic vertebral osteomyelitis in nondrug users.

Authors:  Joan M Nolla; Javier Ariza; Carmen Gómez-Vaquero; Jordi Fiter; Joaquín Bermejo; Josep Valverde; Daniel Roig Escofet; Francesc Gudiol
Journal:  Semin Arthritis Rheum       Date:  2002-02       Impact factor: 5.532

9.  Evaluation of conservative treatment of non specific spondylodiscitis.

Authors:  N Bettini; M Girardo; E Dema; S Cervellati
Journal:  Eur Spine J       Date:  2009-05-05       Impact factor: 3.134

10.  [Urogenic spondylodiscitis].

Authors:  E K Renker; K Möhring; R Abel; C Carstens; B Wiedenhöfer; B Lehner; T Bruckner; M Akbar
Journal:  Orthopade       Date:  2009-04       Impact factor: 1.087

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  6 in total

1.  Spondylodiscitis severity code: scoring system for the classification and treatment of non-specific spondylodiscitis.

Authors:  L Homagk; N Homagk; J R Klauss; K Roehl; G O Hofmann; D Marmelstein
Journal:  Eur Spine J       Date:  2015-04-21       Impact factor: 3.134

Review 2.  [Spondylodiscitis : Current strategies for diagnosis and treatment].

Authors:  I Michiels; M Jäger
Journal:  Orthopade       Date:  2017-09       Impact factor: 1.087

Review 3.  [Infections after reconstructive spinal interventions : How do I deal with them?]

Authors:  Burkhard Lehner; Michael Akbar; Nicholas A Beckmann
Journal:  Orthopade       Date:  2018-04       Impact factor: 1.087

4.  Distribution of HIV-1 in the genomes of AIDS patients.

Authors:  L Tsyba; A V Rynditch; E Boeri; K Jabbari; G Bernardi
Journal:  Cell Mol Life Sci       Date:  2004-03       Impact factor: 9.261

5.  [Dorsolateral access and interbody spinal fusion in spondylodiscitis of the thoracolumbar spine (TLIF technique)].

Authors:  J Madert; M Liem; K-H Frosch; T Niemeyer
Journal:  Oper Orthop Traumatol       Date:  2013-06       Impact factor: 1.154

Review 6.  Treatment algorithm for spontaneous spinal infections: A review of the literature.

Authors:  Fabrizio Gregori; Giovanni Grasso; Giancarlo Iaiani; Nicola Marotta; Fabio Torregrossa; Alessandro Landi
Journal:  J Craniovertebr Junction Spine       Date:  2019 Jan-Mar
  6 in total

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