Literature DB >> 22920099

A derivation of the master equation from path entropy maximization.

Julian Lee1, Steve Pressé.   

Abstract

The master equation and, more generally, Markov processes are routinely used as models for stochastic processes. They are often justified on the basis of randomization and coarse-graining assumptions. Here instead, we derive nth-order Markov processes and the master equation as unique solutions to an inverse problem. We find that when constraints are not enough to uniquely determine the stochastic model, an nth-order Markov process emerges as the unique maximum entropy solution to this otherwise underdetermined problem. This gives a rigorous alternative for justifying such models while providing a systematic recipe for generalizing widely accepted stochastic models usually assumed to follow from the first principles.

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Year:  2012        PMID: 22920099      PMCID: PMC4108628          DOI: 10.1063/1.4743955

Source DB:  PubMed          Journal:  J Chem Phys        ISSN: 0021-9606            Impact factor:   3.488


  9 in total

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Journal:  J Chem Phys       Date:  2012-02-14       Impact factor: 3.488

Review 3.  Generating function methods in single-molecule spectroscopy.

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4.  Generic schemes for single-molecule kinetics. 1: Self-consistent pathway solutions for renewal processes.

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5.  Maximum Caliber: a variational approach applied to two-state dynamics.

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Journal:  J Chem Phys       Date:  2008-05-21       Impact factor: 3.488

6.  "Cross-graining": efficient multi-scale simulation via Markov state models.

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7.  Optimal use of data in parallel tempering simulations for the construction of discrete-state Markov models of biomolecular dynamics.

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8.  Teaching the principles of statistical dynamics.

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Review 9.  Everything you wanted to know about Markov State Models but were afraid to ask.

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  9 in total
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2.  Inferring a network from dynamical signals at its nodes.

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4.  Bistability, non-ergodicity, and inhibition in pairwise maximum-entropy models.

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Review 5.  An introduction to the maximum entropy approach and its application to inference problems in biology.

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  5 in total

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