| Literature DB >> 22918589 |
Matthew Hogg1, Erik Johansson.
Abstract
DNA polymerase ε (Pol ε) is one of three replicative DNA polymerases in eukaryotic cells. Pol ε is a multi-subunit DNA polymerase with many functions. For example, recent studies in yeast have suggested that Pol ε is essential during the initiation of DNA replication and also participates during leading strand synthesis. In this chapter, we will discuss the structure of Pol ε, the individual subunits and their function.Entities:
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Year: 2012 PMID： 22918589 DOI： 10.1007/978-94-007-4572-8_13
Source DB: PubMed Journal: Subcell Biochem ISSN： 0306-0225