Alicia M Goodwill1, Alan J Pearce, Dawson J Kidgell. 1. Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia.
Abstract
INTRODUCTION: We used transcranial magnetic stimulation (TMS) to investigate 3 weeks of unilateral leg strength training on ipsilateral motor cortex (iM1) excitability, and short-latency intracortical inhibition (SICI). METHODS:Right leg dominant participants (n = 14) were randomly divided into either a strength training (ST) or control group. The ST group completed 9 training sessions (4 sets of 6 to 8 repetitions of single right leg squats). RESULTS: We observed a 41% increase in right leg strength, and a 35% increase in strength of the untrained left leg (P < 0.01). There was a significant increase in motor evoked potential (MEP) amplitude recruitment curve for the untrained left leg (P < 0.01). SICI of the iM1 decreased by 21% for the untrained left leg (P < 0.01). CONCLUSIONS: The findings provide evidence for corticomotor adaptation for unilateral leg strength training within the iM1 that is modulated by changes in interhemispheric inhibition.
RCT Entities:
INTRODUCTION: We used transcranial magnetic stimulation (TMS) to investigate 3 weeks of unilateral leg strength training on ipsilateral motor cortex (iM1) excitability, and short-latency intracortical inhibition (SICI). METHODS: Right leg dominant participants (n = 14) were randomly divided into either a strength training (ST) or control group. The ST group completed 9 training sessions (4 sets of 6 to 8 repetitions of single right leg squats). RESULTS: We observed a 41% increase in right leg strength, and a 35% increase in strength of the untrained left leg (P < 0.01). There was a significant increase in motor evoked potential (MEP) amplitude recruitment curve for the untrained left leg (P < 0.01). SICI of the iM1 decreased by 21% for the untrained left leg (P < 0.01). CONCLUSIONS: The findings provide evidence for corticomotor adaptation for unilateral leg strength training within the iM1 that is modulated by changes in interhemispheric inhibition.
Authors: Ela B Plow; David A Cunningham; Corin Bonnett; Dina Gohar; Mehmed Bayram; Alexandria Wyant; Nicole Varnerin; Bernadett Mamone; Vlodek Siemionow; Juliet Hou; Andre Machado; Guang H Yue Journal: J Neurophysiol Date: 2013-09-11 Impact factor: 2.714