Literature DB >> 22896600

Memory CD4(+) T lymphocytes in the gastrointestinal tract are a major source of cell-associated simian immunodeficiency virus in chronic nonpathogenic infection of African green monkeys.

Joern E Schmitz1, Zhong-Min Ma, Emily A Hagan, Andrew B Wilks, Kathryn L Furr, Caitlyn H Linde, Roland C Zahn, Jason M Brenchley, Christopher J Miller, Sallie R Permar.   

Abstract

Simian immunodeficiency virus (SIV) infection of natural hosts is characterized by nonpathogenic chronic viremia, maintenance of gastrointestinal epithelial barrier integrity, and low numbers of target cells. Assessment of cell-associated virus load in T cell subsets in multiple anatomic compartments of chronically SIV-infected sabeus African green monkeys (AGMs) revealed that gastrointestinal memory CD4(+) T lymphocytes are a major source of cell-associated virus and a significant contributor to SIV viremia in AGMs.

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Year:  2012        PMID： 22896600      PMCID： PMC3457182          DOI： 10.1128/JVI.01556-12

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  27 in total

1.  Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection.

Authors:  L A Chakrabarti; S R Lewin; L Zhang; A Gettie; A Luckay; L N Martin; E Skulsky; D D Ho; C Cheng-Mayer; P A Marx
Journal:  J Virol       Date:  2000-02       Impact factor: 5.103

2.  Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts.

Authors:  Ivona Pandrea; Cristian Apetrei; Jason Dufour; Nora Dillon; Joseph Barbercheck; Michael Metzger; Béatrice Jacquelin; Rudolf Bohm; Preston A Marx; Françoise Barre-Sinoussi; Vanessa M Hirsch; Michaela C Müller-Trutwin; Andrew A Lackner; Ronald S Veazey
Journal:  J Virol       Date:  2006-05       Impact factor: 5.103

3.  CD4 and CD8 expressions in African green monkey helper T lymphocytes: implication for resistance to SIV infection.

Authors:  Y Murayama; A Amano; R Mukai; H Shibata; S Matsunaga; H Takahashi; Y Yoshikawa; M Hayami; A Noguchi
Journal:  Int Immunol       Date:  1997-06       Impact factor: 4.823

4.  An African green monkey lacking peripheral CD4 lymphocytes that retains helper T cell activity and coexists with SIVagm.

Authors:  Y Murayama; R Mukai; M Inoue-Murayama; Y Yoshikawa
Journal:  Clin Exp Immunol       Date:  1999-09       Impact factor: 4.330

5.  Correlates of preserved CD4(+) T cell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis.

Authors:  Beth Sumpter; Richard Dunham; Shari Gordon; Jessica Engram; Margaret Hennessy; Audrey Kinter; Mirko Paiardini; Barbara Cervasi; Nichole Klatt; Harold McClure; Jeffrey M Milush; Silvija Staprans; Donald L Sodora; Guido Silvestri
Journal:  J Immunol       Date:  2007-02-01       Impact factor: 5.422

6.  T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis.

Authors:  Jason M Brenchley; Brenna J Hill; David R Ambrozak; David A Price; Francisco J Guenaga; Joseph P Casazza; Janaki Kuruppu; Javaidia Yazdani; Stephen A Migueles; Mark Connors; Mario Roederer; Daniel C Douek; Richard A Koup
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103

7.  High levels of SIVmnd-1 replication in chronically infected Mandrillus sphinx.

Authors:  Ivona Pandrea; Richard Onanga; Christopher Kornfeld; Pierre Rouquet; Olivier Bourry; Stephen Clifford; Paul T Telfer; Kate Abernethy; Lee T W White; Paul Ngari; Michaela Müller-Trutwin; Pierre Roques; Preston A Marx; Francois Simon; Cristian Apetrei
Journal:  Virology       Date:  2003-12-05       Impact factor: 3.616

8.  Microbial translocation is a cause of systemic immune activation in chronic HIV infection.

Authors:  Jason M Brenchley; David A Price; Timothy W Schacker; Tedi E Asher; Guido Silvestri; Srinivas Rao; Zachary Kazzaz; Ethan Bornstein; Olivier Lambotte; Daniel Altmann; Bruce R Blazar; Benigno Rodriguez; Leia Teixeira-Johnson; Alan Landay; Jeffrey N Martin; Frederick M Hecht; Louis J Picker; Michael M Lederman; Steven G Deeks; Daniel C Douek
Journal:  Nat Med       Date:  2006-11-19       Impact factor: 53.440

9.  Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection.

Authors:  Louis J Picker; Shoko I Hagen; Richard Lum; Edward F Reed-Inderbitzin; Lyn M Daly; Andrew W Sylwester; Joshua M Walker; Don C Siess; Michael Piatak; Chenxi Wang; David B Allison; Vernon C Maino; Jeffrey D Lifson; Toshiaki Kodama; Michael K Axthelm
Journal:  J Exp Med       Date:  2004-11-15       Impact factor: 14.307

10.  CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract.

Authors:  Jason M Brenchley; Timothy W Schacker; Laura E Ruff; David A Price; Jodie H Taylor; Gregory J Beilman; Phuong L Nguyen; Alexander Khoruts; Matthew Larson; Ashley T Haase; Daniel C Douek
Journal:  J Exp Med       Date:  2004-09-13       Impact factor: 14.307
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  6 in total

1.  The well-tempered SIV infection: Pathogenesis of SIV infection in natural hosts in the wild, with emphasis on virus transmission and early events post-infection that may contribute to protection from disease progression.

Authors:  Kevin Raehtz; Ivona Pandrea; Cristian Apetrei
Journal:  Infect Genet Evol       Date:  2016-07-06       Impact factor: 3.342

2.  Interleukin-2 Therapy Induces CD4 Downregulation, Which Decreases Circulating CD4 T Cell Counts, in African Green Monkeys.

Authors:  Joseph C Mudd; Molly R Perkins; Sarah R DiNapoli; Vanessa M Hirsch; Jason M Brenchley
Journal:  J Virol       Date:  2016-05-27       Impact factor: 5.103

3.  Cytotoxic T Cell Functions Accumulate When CD4 Is Downregulated by CD4+ T Cells in African Green Monkeys.

Authors:  Carol L Vinton; Alexandra M Ortiz; Nina Calantone; Joseph C Mudd; Claire Deleage; David R Morcock; Sonya Whitted; Jacob D Estes; Vanessa M Hirsch; Jason M Brenchley
Journal:  J Immunol       Date:  2017-04-24       Impact factor: 5.422

Review 4.  Immunopathogenesis of simian immunodeficiency virus infection in nonhuman primates.

Authors:  Joern E Schmitz; Birgit Korioth-Schmitz
Journal:  Curr Opin HIV AIDS       Date:  2013-07       Impact factor: 4.283

5.  Homeostatic cytokines induce CD4 downregulation in African green monkeys independently of antigen exposure to generate simian immunodeficiency virus-resistant CD8αα T cells.

Authors:  Molly R Perkins; Judith A Briant; Nina Calantone; Sonya Whitted; Carol L Vinton; Nichole R Klatt; Ilnour Ourmanov; Alexandra M Ortiz; Vanessa M Hirsch; Jason M Brenchley
Journal:  J Virol       Date:  2014-07-02       Impact factor: 5.103

Review 6.  Host-pathogen interaction in HIV infection.

Authors:  Ankita Chowdhury; Guido Silvestri
Journal:  Curr Opin Immunol       Date:  2013-07-24       Impact factor: 7.486
  6 in total

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