Literature DB >> 23890585

Host-pathogen interaction in HIV infection.

Ankita Chowdhury1, Guido Silvestri.   

Abstract

The host-pathogen interaction is strikingly complex during HIV infection. While several immune effector mechanisms (i.e. cytotoxic T cells, neutralizing antibodies, NK cells, among others) can play a strong antiviral role in vivo, the virus is remarkably able to evade these responses. In addition, the virus preferentially infects and kills activated memory CD4+ T cells, thus exploiting the host antiviral immune response as a source of new cellular targets for infection. Recent advances in understanding (i) how HIV perturbs the host immune system, (ii) how the immune system fights HIV; and (iii) how HIV disease persists when virus replication is suppressed by antiretroviral drugs may hopefully lead to better prevention and treatment strategies for this deadly viral infection.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23890585      PMCID: PMC3775842          DOI: 10.1016/j.coi.2013.07.003

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  72 in total

Review 1.  HIV and inflammation: mechanisms and consequences.

Authors:  Peter W Hunt
Journal:  Curr HIV/AIDS Rep       Date:  2012-06       Impact factor: 5.071

Review 2.  An overview of intracellular interactions between immunodeficiency viruses and their hosts.

Authors:  Paul D Bieniasz
Journal:  AIDS       Date:  2012-06-19       Impact factor: 4.177

3.  Immune responses driven by protective human leukocyte antigen alleles from long-term nonprogressors are associated with low HIV reservoir in central memory CD4 T cells.

Authors:  Benjamin Descours; Veronique Avettand-Fenoel; Catherine Blanc; Assia Samri; Adeline Mélard; Virginie Supervie; Ioannis Theodorou; Guislaine Carcelain; Christine Rouzioux; Brigitte Autran
Journal:  Clin Infect Dis       Date:  2012-03-22       Impact factor: 9.079

4.  Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome.

Authors:  Scott A Handley; Larissa B Thackray; Guoyan Zhao; Rachel Presti; Andrew D Miller; Lindsay Droit; Peter Abbink; Lori F Maxfield; Amal Kambal; Erning Duan; Kelly Stanley; Joshua Kramer; Sheila C Macri; Sallie R Permar; Joern E Schmitz; Keith Mansfield; Jason M Brenchley; Ronald S Veazey; Thaddeus S Stappenbeck; David Wang; Dan H Barouch; Herbert W Virgin
Journal:  Cell       Date:  2012-10-12       Impact factor: 41.582

Review 5.  Towards an HIV cure: a global scientific strategy.

Authors:  Steven G Deeks; Brigitte Autran; Ben Berkhout; Monsef Benkirane; Scott Cairns; Nicolas Chomont; Tae-Wook Chun; Melissa Churchill; Michele Di Mascio; Christine Katlama; Alain Lafeuillade; Alan Landay; Michael Lederman; Sharon R Lewin; Frank Maldarelli; David Margolis; Martin Markowitz; Javier Martinez-Picado; James I Mullins; John Mellors; Santiago Moreno; Una O'Doherty; Sarah Palmer; Marie-Capucine Penicaud; Matija Peterlin; Guido Poli; Jean-Pierre Routy; Christine Rouzioux; Guido Silvestri; Mario Stevenson; Amalio Telenti; Carine Van Lint; Eric Verdin; Ann Woolfrey; John Zaia; Françoise Barré-Sinoussi
Journal:  Nat Rev Immunol       Date:  2012-07-20       Impact factor: 53.106

6.  Innate immune activation enhances hiv acquisition in women, diminishing the effectiveness of tenofovir microbicide gel.

Authors:  Vivek Naranbhai; Salim S Abdool Karim; Marcus Altfeld; Natasha Samsunder; Raveshni Durgiah; Sengeziwe Sibeko; Quarraisha Abdool Karim; William H Carr
Journal:  J Infect Dis       Date:  2012-07-24       Impact factor: 5.226

7.  Memory CD4(+) T lymphocytes in the gastrointestinal tract are a major source of cell-associated simian immunodeficiency virus in chronic nonpathogenic infection of African green monkeys.

Authors:  Joern E Schmitz; Zhong-Min Ma; Emily A Hagan; Andrew B Wilks; Kathryn L Furr; Caitlyn H Linde; Roland C Zahn; Jason M Brenchley; Christopher J Miller; Sallie R Permar
Journal:  J Virol       Date:  2012-08-15       Impact factor: 5.103

8.  Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation.

Authors:  Thomas H Vanderford; Chloe Slichter; Kenneth A Rogers; Benton O Lawson; Rend Obaede; James Else; Francois Villinger; Steven E Bosinger; Guido Silvestri
Journal:  Blood       Date:  2012-05-01       Impact factor: 22.113

9.  CD4 T follicular helper cell dynamics during SIV infection.

Authors:  Constantinos Petrovas; Takuya Yamamoto; Michael Y Gerner; Kristin L Boswell; Kaska Wloka; Emily C Smith; David R Ambrozak; Netanya G Sandler; Katherina J Timmer; Xiaoyong Sun; Li Pan; Amanda Poholek; Srinivas S Rao; Jason M Brenchley; S Munir Alam; Georgia D Tomaras; Mario Roederer; Daniel C Douek; Robert A Seder; Ronald N Germain; Elias K Haddad; Richard A Koup
Journal:  J Clin Invest       Date:  2012-08-27       Impact factor: 14.808

10.  Expansion of HIV-specific T follicular helper cells in chronic HIV infection.

Authors:  Madelene Lindqvist; Jan van Lunzen; Damien Z Soghoian; Bjorn D Kuhl; Srinika Ranasinghe; Gregory Kranias; Michael D Flanders; Samuel Cutler; Naomi Yudanin; Matthias I Muller; Isaiah Davis; Donna Farber; Philip Hartjen; Friedrich Haag; Galit Alter; Julian Schulze zur Wiesch; Hendrik Streeck
Journal:  J Clin Invest       Date:  2012-08-27       Impact factor: 14.808

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  2 in total

1.  Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay.

Authors:  Wim Trypsteen; Pejman Mohammadi; Clarissa Van Hecke; Pieter Mestdagh; Steve Lefever; Yvan Saeys; Pieter De Bleser; Jo Vandesompele; Angela Ciuffi; Linos Vandekerckhove; Ward De Spiegelaere
Journal:  Sci Rep       Date:  2016-10-26       Impact factor: 4.379

Review 2.  Measuring Environmental Exposure to Enteric Pathogens in Low-Income Settings: Review and Recommendations of an Interdisciplinary Working Group.

Authors:  Frederick G B Goddard; Radu Ban; Dana Boyd Barr; Joe Brown; Jennifer Cannon; John M Colford; Joseph N S Eisenberg; Ayse Ercumen; Helen Petach; Matthew C Freeman; Karen Levy; Stephen P Luby; Christine Moe; Amy J Pickering; Jeremy A Sarnat; Jill Stewart; Evan Thomas; Mami Taniuchi; Thomas Clasen
Journal:  Environ Sci Technol       Date:  2020-09-09       Impact factor: 9.028

  2 in total

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