Literature DB >> 22892756

Biomarkers of cancer metastasis through the lymphovascular system: future perspectives.

Stanley P L Leong1, Marlys Witte.   

Abstract

Cancer progression from the primary site to the regional lymph nodes and beyond to the distant sites through the lymphovascular system is genetically determined. In general, sentinel lymph node in the regional lymph nodes is the gateway for metastasis. Biomarkers are becoming increasingly important to define different phases of metastasis. With further understanding of the molecular mechanisms of metastasis, more targets are available for selective therapeutic intervention so that effective therapy can be delivered against cancer in a more personalized approach.

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Year:  2012        PMID： 22892756     DOI： 10.1007/s10585-012-9522-0

Source DB:  PubMed          Journal:  Clin Exp Metastasis        ISSN： 0262-0898            Impact factor:   5.150


  32 in total

1.  Prognostic significance of mitotic rate in localized primary cutaneous melanoma: an analysis of patients in the multi-institutional American Joint Committee on Cancer melanoma staging database.

Authors:  John F Thompson; Seng-Jaw Soong; Charles M Balch; Jeffrey E Gershenwald; Shouluan Ding; Daniel G Coit; Keith T Flaherty; Phyllis A Gimotty; Timothy Johnson; Marcella M Johnson; Stanley P Leong; Merrick I Ross; David R Byrd; Natale Cascinelli; Alistair J Cochran; Alexander M Eggermont; Kelly M McMasters; Martin C Mihm; Donald L Morton; Vernon K Sondak
Journal:  J Clin Oncol       Date:  2011-04-25       Impact factor: 44.544

2.  A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer.

Authors:  Anil Potti; Sayan Mukherjee; Rebecca Petersen; Holly K Dressman; Andrea Bild; Jason Koontz; Robert Kratzke; Mark A Watson; Michael Kelley; Geoffrey S Ginsburg; Mike West; David H Harpole; Joseph R Nevins
Journal:  N Engl J Med       Date:  2006-08-10       Impact factor: 91.245

Review 3.  Personalized medicine in oncology: the future is now.

Authors:  Richard L Schilsky
Journal:  Nat Rev Drug Discov       Date:  2010-05       Impact factor: 84.694

4.  The impact of primary melanoma thickness and microscopic tumor burden in sentinel lymph nodes on melanoma patient survival.

Authors:  Frederick L Baehner; Rui Li; Tyler Jenkins; Jimmy Hwang; Mohammed Kashani-Sabet; Robert E Allen; Stanley P L Leong
Journal:  Ann Surg Oncol       Date:  2011-10-12       Impact factor: 5.344

Review 5.  Cutaneous melanoma: a model to study cancer metastasis.

Authors:  Stanley P L Leong; Jeffrey E Gershenwald; Seng-Jaw Soong; Dirk Schadendorf; Ahmad A Tarhini; Sanjiv Agarwala; Axel Hauschild; Christopher W M Soon; Adil Daud; Mohammed Kashani-Sabet
Journal:  J Surg Oncol       Date:  2011-05-01       Impact factor: 3.454

6.  The Pivotal Role of the Lymphovascular System in Cancer Metastasis: future perspectives.

Authors:  Stanley P L Leong; Marlys Witte
Journal:  J Surg Oncol       Date:  2011-05-01       Impact factor: 3.454

Review 7.  Karnofsky Memorial Lecture. Natural history of small breast cancers.

Authors:  S Hellman
Journal:  J Clin Oncol       Date:  1994-10       Impact factor: 44.544

8.  Markers and tissue resources for melanoma: meeting report.

Authors:  Dorothea Becker; Martin C Mihm; Stephen M Hewitt; Vernon K Sondak; Jane W Fountain; Magdalena Thurin
Journal:  Cancer Res       Date:  2006-11-15       Impact factor: 12.701

9.  Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer.

Authors:  Rafael G Amado; Michael Wolf; Marc Peeters; Eric Van Cutsem; Salvatore Siena; Daniel J Freeman; Todd Juan; Robert Sikorski; Sid Suggs; Robert Radinsky; Scott D Patterson; David D Chang
Journal:  J Clin Oncol       Date:  2008-03-03       Impact factor: 44.544

10.  Paradigm of metastasis for melanoma and breast cancer based on the sentinel lymph node experience.

Authors:  Stanley P L Leong
Journal:  Ann Surg Oncol       Date:  2004-03       Impact factor: 5.344
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  2 in total

1.  Is the non-sentinel lymph node compartment the next site for melanoma progression from the sentinel lymph node compartment in the regional nodal basin?

Authors:  Andrei Rios-Cantu; Ying Lu; Victor Melendez-Elizondo; Michael Chen; Alejandra Gutierrez-Range; Niloofar Fadaki; Suresh Thummala; Carla West-Coffee; James Cleaver; Mohammed Kashani-Sabet; Stanley P L Leong
Journal:  Clin Exp Metastasis       Date:  2017-07-11       Impact factor: 5.150

2.  Loss of PCDH9 is associated with the differentiation of tumor cells and metastasis and predicts poor survival in gastric cancer.

Authors:  Ying Chen; Honggang Xiang; Yingfan Zhang; Jiejun Wang; Guanzhen Yu
Journal:  Clin Exp Metastasis       Date:  2015-04-14       Impact factor: 5.150
  2 in total

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