Literature DB >> 22883621

Cullin RING ligases: glommed by glomulin.

Ventzislava A Hristova1, Daniel K Stringer, Allan M Weissman.   

Abstract

Cullin ring ligases (CRLs) constitute the largest group of RING finger ubiquitin ligases. Two recent studies in Molecular Cell describe glomulin as a CRL1 inhibitor that blocks interactions with its ubiquitin-conjugating enzyme (E2) (Duda et al., 2012; Tron et al., 2012). These findings and their significance are discussed.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22883621      PMCID： PMC3448943          DOI： 10.1016/j.molcel.2012.07.025

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  10 in total

Review 1.  The SCF ubiquitin ligase: insights into a molecular machine.

Authors:  Timothy Cardozo; Michele Pagano
Journal:  Nat Rev Mol Cell Biol       Date:  2004-09       Impact factor: 94.444

2.  The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.

Authors:  Adriana E Tron; Takehiro Arai; David M Duda; Hiroshi Kuwabara; Jennifer L Olszewski; Yuko Fujiwara; Brittany N Bahamon; Sabina Signoretti; Brenda A Schulman; James A DeCaprio
Journal:  Mol Cell       Date:  2012-03-08       Impact factor: 17.970

3.  WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins.

Authors:  Natasha Pashkova; Lokesh Gakhar; Stanley C Winistorfer; Liping Yu; S Ramaswamy; Robert C Piper
Journal:  Mol Cell       Date:  2010-11-12       Impact factor: 17.970

Review 4.  Regulating the regulator: negative regulation of Cbl ubiquitin ligases.

Authors:  Philip E Ryan; Gareth C Davies; Marion M Nau; Stanley Lipkowitz
Journal:  Trends Biochem Sci       Date:  2006-01-06       Impact factor: 13.807

Review 5.  Regulation of catalytic activities of HECT ubiquitin ligases.

Authors:  Younghoon Kee; Jon M Huibregtse
Journal:  Biochem Biophys Res Commun       Date:  2007-01-16       Impact factor: 3.575

Review 6.  The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation.

Authors:  Allan M Weissman; Nitzan Shabek; Aaron Ciechanover
Journal:  Nat Rev Mol Cell Biol       Date:  2011-08-23       Impact factor: 94.444

7.  Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis.

Authors:  Takehiro Arai; Jocelyn S Kasper; Jeffrey R Skaar; Syed Hamid Ali; Chiaki Takahashi; James A DeCaprio
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-06       Impact factor: 11.205

8.  Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface.

Authors:  David M Duda; Jennifer L Olszewski; Adriana E Tron; Michal Hammel; Lester J Lambert; M Brett Waddell; Tanja Mittag; James A DeCaprio; Brenda A Schulman
Journal:  Mol Cell       Date:  2012-06-28       Impact factor: 17.970

Review 9.  Structural regulation of cullin-RING ubiquitin ligase complexes.

Authors:  David M Duda; Daniel C Scott; Matthew F Calabrese; Erik S Zimmerman; Ning Zheng; Brenda A Schulman
Journal:  Curr Opin Struct Biol       Date:  2011-02-01       Impact factor: 6.809

Review 10.  The cullin protein family.

Authors:  Antonio Sarikas; Thomas Hartmann; Zhen-Qiang Pan
Journal:  Genome Biol       Date:  2011-04-28       Impact factor: 13.583
  10 in total
  2 in total

1.  Shigella hijacks the glomulin-cIAPs-inflammasome axis to promote inflammation.

Authors:  Shiho Suzuki; Toshihiko Suzuki; Hitomi Mimuro; Tsunehiro Mizushima; Chihiro Sasakawa
Journal:  EMBO Rep       Date:  2017-11-30       Impact factor: 8.807

2.  Genetic syndromes with vascular malformations - update on molecular background and diagnostics.

Authors:  Adam Ustaszewski; Joanna Janowska-Głowacka; Katarzyna Wołyńska; Anna Pietrzak; Magdalena Badura-Stronka
Journal:  Arch Med Sci       Date:  2020-02-25       Impact factor: 3.318
  2 in total

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