Literature DB >> 22869634

Treatment of granulomatous amoebic encephalitis with voriconazole and miltefosine in an immunocompetent soldier.

Duncan Webster1, Imran Umar, Imram Umar, George Kolyvas, Juan Bilbao, Marie-Christine Guiot, Kevin Duplisea, Yvonne Qvarnstrom, Govinda S Visvesvara.   

Abstract

A 38-year-old male immunocompetent soldier developed generalized seizures. He underwent surgical debulking and a progressive demyelinating pseudotumor was identified. Serology and molecular testing confirmed a diagnosis of granulomatous amoebic encephalitis caused by Acanthamoeba sp. in this immunocompetent male. The patient was treated with oral voriconazole and miltefosine with Acanthamoeba titers returning to control levels and serial imaging demonstrating resolution of the residual lesion.

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Year:  2012        PMID: 22869634      PMCID: PMC3516325          DOI: 10.4269/ajtmh.2012.12-0100

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  26 in total

1.  Successful treatment of Acanthamoeba meningitis with combination oral antimicrobials.

Authors:  T Singhal; A Bajpai; V Kalra; S K Kabra; J C Samantaray; G Satpathy; A K Gupta
Journal:  Pediatr Infect Dis J       Date:  2001-06       Impact factor: 2.129

Review 2.  Leishmaniasis in the United States: treatment in 2012.

Authors:  Henry W Murray
Journal:  Am J Trop Med Hyg       Date:  2012-03       Impact factor: 2.345

3.  Acanthameba meningitis with successful outcome.

Authors:  Ajit Saxena; Sumit Mittal; Purbi Burman; Pankaj Garg
Journal:  Indian J Pediatr       Date:  2009-11-12       Impact factor: 1.967

4.  Oral miltefosine for Indian visceral leishmaniasis.

Authors:  Shyam Sundar; T K Jha; C P Thakur; Juergen Engel; Herbert Sindermann; Christina Fischer; Klaus Junge; Anthony Bryceson; Jonathan Berman
Journal:  N Engl J Med       Date:  2002-11-28       Impact factor: 91.245

5.  Granulomatous amebic encephalitis in a child with acute lymphoblastic leukemia successfully treated with multimodal antimicrobial therapy and hyperbaric oxygen.

Authors:  P Maritschnegg; P Sovinz; H Lackner; M Benesch; A Nebl; W Schwinger; J Walochnik; C Urban
Journal:  J Clin Microbiol       Date:  2010-11-17       Impact factor: 5.948

6.  Granulomatous amebic encephalitis in a patient with AIDS: isolation of acanthamoeba sp. Group II from brain tissue and successful treatment with sulfadiazine and fluconazole.

Authors:  M Seijo Martinez; G Gonzalez-Mediero; P Santiago; A Rodriguez De Lope; J Diz; C Conde; G S Visvesvara
Journal:  J Clin Microbiol       Date:  2000-10       Impact factor: 5.948

7.  Cytotoxic activities of alkylphosphocholines against clinical isolates of Acanthamoeba spp.

Authors:  Julia Walochnik; Michael Duchêne; Karin Seifert; Andreas Obwaller; Thomas Hottkowitz; Gerhard Wiedermann; Hansjörg Eibl; Horst Aspöck
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

Review 8.  Free-living amoebae as opportunistic and non-opportunistic pathogens of humans and animals.

Authors:  Frederick L Schuster; Govinda S Visvesvara
Journal:  Int J Parasitol       Date:  2004-08       Impact factor: 3.981

9.  Acute granulomatous acanthamoeba encephalitis in an immunocompetent patient.

Authors:  Peter Lackner; Ronny Beer; Gregor Broessner; Raimund Helbok; Bettina Pfausler; Christian Brenneis; Herbert Auer; Julia Walochnik; Erich Schmutzhard
Journal:  Neurocrit Care       Date:  2010-02       Impact factor: 3.210

Review 10.  Biology and pathogenesis of Acanthamoeba.

Authors:  Ruqaiyyah Siddiqui; Naveed Ahmed Khan
Journal:  Parasit Vectors       Date:  2012-01-10       Impact factor: 3.876

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  22 in total

1.  Emerging and reemerging neurologic infections.

Authors:  Felicia C Chow; Carol A Glaser
Journal:  Neurohospitalist       Date:  2014-10

2.  Tigecycline inhibits proliferation of Acanthamoeba castellanii.

Authors:  Bijay Kumar Jha; Incheol Seo; Hyun-Hee Kong; Seong-Il Suh; Min-Ho Suh; Won-Ki Baek
Journal:  Parasitol Res       Date:  2015-01-07       Impact factor: 2.289

3.  Cysticidal activity of antifungals against different genotypes of Acanthamoeba.

Authors:  Alfonso Iovieno; Darlene Miller; Dolena R Ledee; Eduardo C Alfonso
Journal:  Antimicrob Agents Chemother       Date:  2014-07-07       Impact factor: 5.191

Review 4.  The Development of Drugs against Acanthamoeba Infections.

Authors:  Ruqaiyyah Siddiqui; Yousuf Aqeel; Naveed Ahmed Khan
Journal:  Antimicrob Agents Chemother       Date:  2016-10-21       Impact factor: 5.191

5.  Chloroquine has a cytotoxic effect on Acanthamoeba encystation through modulation of autophagy.

Authors:  Bijay Kumar Jha; Hui-Jung Jung; Incheol Seo; Hyun Ah Kim; Seong-Il Suh; Min-Ho Suh; Won-Ki Baek
Journal:  Antimicrob Agents Chemother       Date:  2014-08-11       Impact factor: 5.191

6.  Acanthamoeba endophthalmitis during treatment for cutaneous disease in a renal transplant patient.

Authors:  Allison Kutner; Margaret Aldrich; Sarju Patel; Joann J Kang; Bijal Amin; Ranon Mann; Ibne Karim M Ali; Roosecelis Brasil Martines; Jennifer Rittenhouse Cope; Graciela O De Boccardo; Yoram A Puius
Journal:  Transpl Infect Dis       Date:  2018-02-12       Impact factor: 2.228

7.  Artemether Exhibits Amoebicidal Activity against Acanthamoeba castellanii through Inhibition of the Serine Biosynthesis Pathway.

Authors:  Yihong Deng; Wei Ran; Suqin Man; Xueping Li; Hongjian Gao; Wei Tang; Hiroshi Tachibana; Xunjia Cheng
Journal:  Antimicrob Agents Chemother       Date:  2015-05-26       Impact factor: 5.191

8.  In vitro efficacy of corifungin against Acanthamoeba castellanii trophozoites and cysts.

Authors:  Anjan Debnath; Josefino B Tunac; Angélica Silva-Olivares; Silvia Galindo-Gómez; Mineko Shibayama; James H McKerrow
Journal:  Antimicrob Agents Chemother       Date:  2013-12-23       Impact factor: 5.191

9.  In vitro efficacies of clinically available drugs against growth and viability of an Acanthamoeba castellanii keratitis isolate belonging to the T4 genotype.

Authors:  Abdul Mannan Baig; Junaid Iqbal; Naveed Ahmed Khan
Journal:  Antimicrob Agents Chemother       Date:  2013-05-13       Impact factor: 5.191

Review 10.  CYP51 as drug targets for fungi and protozoan parasites: past, present and future.

Authors:  Galina I Lepesheva; Laura Friggeri; Michael R Waterman
Journal:  Parasitology       Date:  2018-04-12       Impact factor: 3.234

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