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Literature DB >> 25001304

Cysticidal activity of antifungals against different genotypes of Acanthamoeba.

Alfonso Iovieno¹, Darlene Miller², Dolena R Ledee², Eduardo C Alfonso².

Abstract

Antifungal drugs have been proposed as a novel treatment for Acanthamoeba keratitis. The cysticidal activity of several antifungal compounds was tested against different genotypes of culture collection and clinical isolates of Acanthamoeba. Only voriconazole and posaconazole were found to be cysticidal, with no differences in activity observed between clinical and culture collection isolates.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2014 PMID： 25001304 PMCID： PMC4135811 DOI： 10.1128/AAC.02635-14

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

18 in total

1. Successful treatment of chronic stromal acanthamoeba keratitis with oral voriconazole monotherapy.

Authors: Elmer Y Tu; Charlotte E Joslin; Megan E Shoff
Journal: Cornea Date: 2010-09 Impact factor: 2.651

2. Extraction of Acanthamoeba DNA by use of Chelex resin.

Authors: Alfonso Iovieno; Darlene Miller; James Lonnen; Simon Kilvington; Eduardo C Alfonso
Journal: J Clin Microbiol Date: 2010-11-17 Impact factor: 5.948

3. Clinical evaluation of the Sensititre YeastOne colorimetric antifungal panel for antifungal susceptibility testing of the echinocandins anidulafungin, caspofungin, and micafungin.

Authors: M A Pfaller; V Chaturvedi; D J Diekema; M A Ghannoum; N M Holliday; S B Killian; C C Knapp; S A Messer; A Miskov; R Ramani
Journal: J Clin Microbiol Date: 2008-05-07 Impact factor: 5.948

Review 4. Acanthamoeba keratitis: diagnosis and treatment update 2009.

Authors: John K G Dart; Valerie P J Saw; Simon Kilvington
Journal: Am J Ophthalmol Date: 2009-08-05 Impact factor: 5.258

5. In vitro antifungal susceptibility testing of filamentous fungi with Sensititre Yeast One.

Authors: A J Carrillo-Muñoz; G Quindós; M Ruesga; O del Valle; J Pemán; E Cantón; J M Hernández-Molina; P Santos
Journal: Mycoses Date: 2006-07 Impact factor: 4.377

6. Effect of caspofungin on trophozoites and cysts of three species of Acanthamoeba.

Authors: Sabrina Bouyer; Christine Imbert; Gyslaine Daniault; Estelle Cateau; Marie-Hélène Rodier
Journal: J Antimicrob Chemother Date: 2006-10-31 Impact factor: 5.790

7. Persistently culture positive acanthamoeba keratitis: in vivo resistance and in vitro sensitivity.

Authors: Juan J Pérez-Santonja; Simon Kilvington; Reanne Hughes; Adnan Tufail; Melville Matheson; John K G Dart
Journal: Ophthalmology Date: 2003-08 Impact factor: 12.079

8. Treatment with voriconazole in 3 eyes with resistant Acanthamoeba keratitis.

Authors: Stacy Bang; Erica Edell; Allen O Eghrari; John D Gottsch
Journal: Am J Ophthalmol Date: 2009-10-28 Impact factor: 5.258

9. Molecular identification of t4 and t5 genotypes in isolates from acanthamoeba keratitis patients.

Authors: D R Ledee; A Iovieno; D Miller; N Mandal; M Diaz; J Fell; M E Fini; E C Alfonso
Journal: J Clin Microbiol Date: 2009-03-25 Impact factor: 5.948

10. Voriconazole as a first-line treatment against potentially pathogenic Acanthamoeba strains from Peru.

Authors: Alfonso Martín Cabello-Vílchez; Carmen M Martín-Navarro; Atteneri López-Arencibia; María Reyes-Batlle; Ines Sifaoui; Basilio Valladares; José E Piñero; Jacob Lorenzo-Morales
Journal: Parasitol Res Date: 2013-11-22 Impact factor: 2.289

10 in total

1. Dendrite-like anterior stromal keratitis coinfected with Acanthamoeba and Pseudomonas in an orthokeratology contact lens wearer.

Authors: Chih-Chien Hsu
Journal: Taiwan J Ophthalmol Date: 2019 Apr-Jun

2. Acanthamoeba genotypes T3 and T4 as causative agents of amoebic keratitis in Mexico.

Authors: Maritza Omaña-Molina; Virginia Vanzzini-Zago; Dolores Hernandez-Martinez; Arturo Gonzalez-Robles; Lizbeth Salazar-Villatoro; Elizabeth Ramirez-Flores; Eric Oregon-Miranda; Jacob Lorenzo-Morales; Adolfo Martinez-Palomo
Journal: Parasitol Res Date: 2015-11-19 Impact factor: 2.289

3. Fluorinated Sterols Are Suicide Inhibitors of Ergosterol Biosynthesis and Growth in Trypanosoma brucei.

Authors: David J Leaver; Presheet Patkar; Ujjal K Singha; Matthew B Miller; Brad A Haubrich; Minu Chaudhuri; W David Nes
Journal: Chem Biol Date: 2015-10-22

4. Acanthamoeba Keratitis: an update on amebicidal and cysticidal drug screening methodologies and potential treatment with azole drugs.

Authors: Brian Shing; Mina Balen; James H McKerrow; Anjan Debnath
Journal: Expert Rev Anti Infect Ther Date: 2021-05-19 Impact factor: 5.091

5. Development of a Machine Learning-Based Cysticidal Assay and Identification of an Amebicidal and Cysticidal Marine Microbial Metabolite against Acanthamoeba.

Authors: Brian Shing; Mina Balen; William Fenical; Anjan Debnath
Journal: Microbiol Spectr Date: 2022-04-25

10. Evaluation of Amebicidal and Cysticidal Activities of Antifungal Drug Isavuconazonium Sulfate against Acanthamoeba T4 Strains.

Authors: Brian Shing; Mina Balen; Anjan Debnath
Journal: Pharmaceuticals (Basel) Date: 2021-12-11