Literature DB >> 22864536

Taste alteration in breast cancer patients treated with taxane chemotherapy: experience, effect, and coping strategies.

Rebecca M Speck1, Angela DeMichele, John T Farrar, Sean Hennessy, Jun J Mao, Margaret G Stineman, Frances K Barg.   

Abstract

PURPOSE: This study examined the experience and coping strategies for taste alteration in female breast cancer patients treated with docetaxel or paclitaxel.
METHODS: A purposive sample of 25 patients currently receiving docetaxel or paclitaxel or within 6 months of having completed treatment was recruited. Semi-structured interviews and patient-level data were utilized for this exploratory descriptive study. Interview data were analyzed with the constant comparative method; patient-level data were abstracted from the electronic medical record.
RESULTS: Of all side effects reported from taxanes, the most common was taste alteration (8 of 10 docetaxel patients, 3 of 15 paclitaxel patients). Women that experience taste alteration chose not to eat as much, ate on an irregular schedule, and/or lost interest in preparing meals for themselves and/or their family. Women adopted a variety of new behaviors to deal with the taste alteration and its effects, including trying new recipes, eating strongly flavored foods, honoring specific food cravings, eating candy before meals, cutting food with lemon, drinking sweetened drinks, using plastic eating utensils, drinking from a straw, brushing their teeth and tongue before meals, and using baking soda and salt wash or antibacterial mouthwash.
CONCLUSIONS: Taste alteration affects breast cancer patients' lives, and they develop management strategies to deal with the effect. While some self-management strategies can be seen as positively adaptive, the potential for increased caloric consumption and poor eating behaviors associated with some coping strategies may be a cause for concern given the observation of weight gain during breast cancer treatment and association of obesity with poor treatment outcomes in breast cancer patients. Further studies are warranted to determine the overall burden of this symptom and measurement of cancer and non-cancer-related consequences of these behavioral adaptations.

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Year:  2012        PMID: 22864536     DOI: 10.1007/s00520-012-1551-3

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  28 in total

1.  Effect of chemotherapy on taste sensation in patients with disseminated malignant melanoma.

Authors:  N H Mulder; J M Smit; W M Kreumer; J Bouman; D T Sleijfer; W Veeger; H Schraffordt Koops
Journal:  Oncology       Date:  1983       Impact factor: 2.935

2.  Quality of life, taste, olfactory and oral function following high-dose chemotherapy and allogeneic hematopoietic cell transplantation.

Authors:  J B Epstein; N Phillips; J Parry; M S Epstein; T Nevill; P Stevenson-Moore
Journal:  Bone Marrow Transplant       Date:  2002-12       Impact factor: 5.483

3.  Taste changes experienced by patients receiving chemotherapy.

Authors:  R S Wickham; M Rehwaldt; C Kefer; S Shott; K Abbas; E Glynn-Tucker; C Potter; C Blendowski
Journal:  Oncol Nurs Forum       Date:  1999-05       Impact factor: 2.172

4.  Obesity and outcomes in premenopausal and postmenopausal breast cancer.

Authors:  Sherene Loi; Roger L Milne; Michael L Friedlander; Margaret R E McCredie; Graham G Giles; John L Hopper; Kelly-Anne Phillips
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2005-07       Impact factor: 4.254

5.  Measuring the side effects of taxane therapy in oncology: the functional assesment of cancer therapy-taxane (FACT-taxane).

Authors:  David Cella; Amy Peterman; Stacie Hudgens; Kimberly Webster; Mark A Socinski
Journal:  Cancer       Date:  2003-08-15       Impact factor: 6.860

6.  Self-care strategies to cope with taste changes after chemotherapy.

Authors:  Maureen Rehwaldt; Rita Wickham; Sandy Purl; Joseph Tariman; Carol Blendowski; Susan Shott; Mary Lappe
Journal:  Oncol Nurs Forum       Date:  2009-03       Impact factor: 2.172

7.  The effect of body mass index on overall and disease-free survival in node-positive breast cancer patients treated with docetaxel and doxorubicin-containing adjuvant chemotherapy: the experience of the BIG 02-98 trial.

Authors:  Evandro de Azambuja; Worta McCaskill-Stevens; Prudence Francis; Emmanuel Quinaux; John P A Crown; Malou Vicente; Rosa Giuliani; Bo Nordenskjöld; Jorge Gutiérez; Michael Andersson; Mireia Margeli Vila; Raimund Jakesz; Jan Demol; Joanna Dewar; Armando Santoro; Ana Lluch; Steven Olsen; Richard D Gelber; Angelo Di Leo; Martine Piccart-Gebhart
Journal:  Breast Cancer Res Treat       Date:  2010-01       Impact factor: 4.872

8.  Chemosensory changes experienced by patients undergoing cancer chemotherapy: a qualitative interview study.

Authors:  Britt-Marie Bernhardson; Carol Tishelman; Lars Erik Rutqvist
Journal:  J Pain Symptom Manage       Date:  2007-07-05       Impact factor: 3.612

9.  Body mass index as a prognostic feature in operable breast cancer: the International Breast Cancer Study Group experience.

Authors:  G Berclaz; S Li; K N Price; A S Coates; M Castiglione-Gertsch; C-M Rudenstam; S B Holmberg; J Lindtner; D Erien; J Collins; R Snyder; B Thürlimann; M F Fey; C Mendiola; I Dudley Werner; E Simoncini; D Crivellari; R D Gelber; A Goldhirsch
Journal:  Ann Oncol       Date:  2004-06       Impact factor: 32.976

10.  Oral mucosal lesions, microbial changes, and taste disturbances induced by adjuvant chemotherapy in breast cancer patients.

Authors:  Siri Beier Jensen; Henning T Mouridsen; Olav J Bergmann; Jesper Reibel; Nils Brünner; Birgitte Nauntofte
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2008-06-13
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  22 in total

1.  Dietary experiences and support needs of women who gain weight following chemotherapy for breast cancer.

Authors:  Alastair Kwok; Claire Palermo; Anna Boltong
Journal:  Support Care Cancer       Date:  2014-11-16       Impact factor: 3.603

Review 2.  Understanding the impact of taste changes in oncology care.

Authors:  Joel B Epstein; Gregory Smutzer; Richard L Doty
Journal:  Support Care Cancer       Date:  2016-01-28       Impact factor: 3.603

3.  Changes in taste and food preferences in breast cancer patients receiving chemotherapy: a pilot study.

Authors:  Yeon-Hee Kim; Gun Min Kim; Sungtaek Son; Mina Song; Sangun Park; Hyun Cheol Chung; Seung-Min Lee
Journal:  Support Care Cancer       Date:  2019-06-22       Impact factor: 3.603

Review 4.  Dermatological adverse events with taxane chemotherapy.

Authors:  Vincent Sibaud; Nicole R Lebœuf; Henri Roche; Viswanath R Belum; Laurence Gladieff; Marion Deslandres; Marion Montastruc; Audrey Eche; Emmanuelle Vigarios; Florence Dalenc; Mario E Lacouture
Journal:  Eur J Dermatol       Date:  2016-10-01       Impact factor: 3.328

Review 5.  Energy balance and metabolism after cancer treatment.

Authors:  Emily S Tonorezos; Lee W Jones
Journal:  Semin Oncol       Date:  2013-12       Impact factor: 4.929

6.  Taste Alteration in Patients Receiving Chemotherapy.

Authors:  Elif Sözeri; Sevinç Kutlutürkan
Journal:  J Breast Health       Date:  2015-04-01

7.  Changes in taste among pediatric patients with cancer and hematopoietic stem cell transplantation recipients.

Authors:  Robyn Loves; Erin Plenert; Vivian Tomlinson; Sasha Palmert; Gloria Green; Tal Schechter; Deborah Tomlinson; Emily Vettese; Sue Zupanec; L Lee Dupuis; Lillian Sung
Journal:  Qual Life Res       Date:  2019-07-01       Impact factor: 4.147

8.  Taste alterations during neo/adjuvant chemotherapy and subsequent follow-up in breast cancer patients: a prospective single-center clinical study.

Authors:  Rebecca Pedersini; Manuel Zamparini; Sara Bosio; Pierluigi di Mauro; Antonella Turla; Sara Monteverdi; Alessandra Zanini; Vito Amoroso; Lucia Vassalli; Deborah Cosentini; Salvatore Grisanti; Edda Lucia Simoncini; Alfredo Berruti
Journal:  Support Care Cancer       Date:  2022-05-11       Impact factor: 3.603

9.  Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: children and adolescents.

Authors:  Juliana Moura Nabarrete; Andrea Z Pereira; Adriana Garófolo; Adriana Seber; Angela Mandelli Venancio; Carlos Eduardo Setanni Grecco; Carmem Maria Sales Bonfim; Claudia Harumi Nakamura; Daieni Fernandes; Denise Johnsson Campos; Fernanda Luisa Ceragioli Oliveira; Flávia Krüger Cousseiro; Flávia Feijó Panico Rossi; Jocemara Gurmini; Karina Helena Canton Viani; Luciana Fernandes Guterres; Luiz Fernando Alves Lima Mantovani; Luiz Guilherme Darrigo Junior; Maria Isabel Brandão Pires E Albuquerque; Melina Brumatti; Mirella Aparecida Neves; Natália Duran; Neysimelia Costa Villela; Victor Gottardello Zecchin; Juliana Folloni Fernandes
Journal:  Einstein (Sao Paulo)       Date:  2021-12-10

10.  Awareness of dysgeusia and gustatory tests in patients undergoing chemotherapy for breast cancer.

Authors:  Sayaka Kuba; Rie Fujiyama; Kosho Yamanouchi; Michi Morita; Chika Sakimura; Toshiko Hatachi; Megumi Matsumoto; Hiroshi Yano; Mitsuhisa Takatsuki; Naomi Hayashida; Takeshi Nagayasu; Susumu Eguchi
Journal:  Support Care Cancer       Date:  2018-05-12       Impact factor: 3.603

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