OBJECTIVES: To document the stability, concurrent validity, and clinical correlates of two fatigability severity measures as recommended by the American Geriatrics Society. DESIGN: Descriptive, cross-sectional. SETTING: Two independent living and one community senior centers. PARTICIPANTS: Forty-three participants, with an average age 85 ± 6. MEASUREMENTS: Perceived fatigability severity was quantified by directly asking participants to report change in energy after a standardized 10-minute walk at a self-selected pace. Performance fatigability severity was defined as a ratio of change in walking speed to total distance walked. The walk test was repeated within 2 weeks to assess stability. Total daily physical activity (PA) was measured over 7 consecutive days using a waist-worn accelerometer. Frailty was measured using the Vulnerable Elders Survey interview scale, and gait speed was measured using a standardized 25-feet walk test. RESULTS: The perceived and performance fatigability severity measures were significantly correlated (correlation coefficient (r) = 0.94, P < .001) and stable over two assessments (r = 0.82 and 0.85, P < .001). Both fatigability severity measures were significantly correlated with PA level (r = -0.42 and r = -0.44, respectively, P = .02), frailty (r = 0.47 and 0.53, respectively, P = .001) and gait speed (r = -0.45, P = .003 and r = -0.54, P = .001, respectively). CONCLUSION: The methodology described in this study permits the calculation of two highly correlated fatigability severity scores, which summarize the relationship between a person's change in self-reported tiredness or change in physical performance and concurrently measured PA. The fatigability severity scores are reproducible and correlated with clinical measures predictive of decline. The methods used to quantify fatigability severity can be implemented during a brief assessment (<15 minutes) and should be useful in the design and evaluation of interventions to increase PA in older adults at risk of functional decline.
OBJECTIVES: To document the stability, concurrent validity, and clinical correlates of two fatigability severity measures as recommended by the American Geriatrics Society. DESIGN: Descriptive, cross-sectional. SETTING: Two independent living and one community senior centers. PARTICIPANTS: Forty-three participants, with an average age 85 ± 6. MEASUREMENTS: Perceived fatigability severity was quantified by directly asking participants to report change in energy after a standardized 10-minute walk at a self-selected pace. Performance fatigability severity was defined as a ratio of change in walking speed to total distance walked. The walk test was repeated within 2 weeks to assess stability. Total daily physical activity (PA) was measured over 7 consecutive days using a waist-worn accelerometer. Frailty was measured using the Vulnerable Elders Survey interview scale, and gait speed was measured using a standardized 25-feet walk test. RESULTS: The perceived and performance fatigability severity measures were significantly correlated (correlation coefficient (r) = 0.94, P < .001) and stable over two assessments (r = 0.82 and 0.85, P < .001). Both fatigability severity measures were significantly correlated with PA level (r = -0.42 and r = -0.44, respectively, P = .02), frailty (r = 0.47 and 0.53, respectively, P = .001) and gait speed (r = -0.45, P = .003 and r = -0.54, P = .001, respectively). CONCLUSION: The methodology described in this study permits the calculation of two highly correlated fatigability severity scores, which summarize the relationship between a person's change in self-reported tiredness or change in physical performance and concurrently measured PA. The fatigability severity scores are reproducible and correlated with clinical measures predictive of decline. The methods used to quantify fatigability severity can be implemented during a brief assessment (<15 minutes) and should be useful in the design and evaluation of interventions to increase PA in older adults at risk of functional decline.
Authors: Maciej S Buchowski; Sandra F Simmons; Lauren E Whitaker; James Powers; Linda Beuscher; Leena Choi; T Alp Ikizler; Kong Chen; John F Shnelle Journal: Age (Dordr) Date: 2011-11-24
Authors: Neil B Alexander; George E Taffet; Frances McFarland Horne; Basil A Eldadah; Luigi Ferrucci; Susan Nayfield; Stephanie Studenski Journal: J Am Geriatr Soc Date: 2010-05 Impact factor: 5.562
Authors: Stephanie Studenski; Subashan Perera; Kushang Patel; Caterina Rosano; Kimberly Faulkner; Marco Inzitari; Jennifer Brach; Julie Chandler; Peggy Cawthon; Elizabeth Barrett Connor; Michael Nevitt; Marjolein Visser; Stephen Kritchevsky; Stefania Badinelli; Tamara Harris; Anne B Newman; Jane Cauley; Luigi Ferrucci; Jack Guralnik Journal: JAMA Date: 2011-01-05 Impact factor: 56.272
Authors: Lillian Min; William Yoon; Jeff Mariano; Neil S Wenger; Marc N Elliott; Caren Kamberg; Debra Saliba Journal: J Am Geriatr Soc Date: 2009-09-28 Impact factor: 5.562
Authors: Madlyn I Frisard; Jennifer M Fabre; Ryan D Russell; Christina M King; James P DeLany; Robert H Wood; Eric Ravussin Journal: J Gerontol A Biol Sci Med Sci Date: 2007-07 Impact factor: 6.053
Authors: Alina Ionela Palimaru; William E Cunningham; Marcus Dillistone; Arturo Vargas-Bustamante; Honghu Liu; Ron D Hays Journal: Arch Phys Med Rehabil Date: 2018-04-26 Impact factor: 3.966
Authors: Catherine A Richardson; Nancy W Glynn; Luigi G Ferrucci; Dawn C Mackey Journal: J Gerontol A Biol Sci Med Sci Date: 2014-09-04 Impact factor: 6.053
Authors: Eleanor M Simonsick; Jennifer A Schrack; Adam J Santanasto; Stephanie A Studenski; Luigi Ferrucci; Nancy W Glynn Journal: J Am Geriatr Soc Date: 2018-10-13 Impact factor: 5.562
Authors: Laura M Pérez; Marta Roqué; Nancy W Glynn; Adam J Santanasto; Maria Ramoneda; Maria T Molins; Laura Coll-Planas; Patricia Vidal; Marco Inzitari Journal: Aging Clin Exp Res Date: 2018-05-08 Impact factor: 3.636