OBJECTIVE: To study the outcome of blastocysts showing expansion on day 5 and transferred on day 5 or 6, in comparison with those unexpanded and transferred on day 6. STUDY DESIGN: Prospective cohort of 221 women prepared for BET classified into three groups according to timing of blastocyst expansion and day of embryo transfer. Group I; with expanded blastocysts on day 5 having day 5 transfer, group II; with expanded blastocysts on day 5 having day 6 transfer and group III ; with delayed expansion undergoing day 6 BET. RESULTS: Implantation rates, pregnancy rates, ongoing pregnancy rates, and live birth rates in the first 2 groups were almost double the rates in the third group. The figures for implantation rates were 40 % in the first two groups vs. 19 % in the third group (P < 0.05). Pregnancy rates were 60.9 % and 64 % vs. 31.8 % (P < 0.05) and ongoing pregnancy/ live-birth rates were 52.3 % & 56 % vs. 27.3 %. CONCLUSION: The current study reports better implantation and pregnancy rates with earlier expanding blastocysts regardless of the time of transfer.
OBJECTIVE: To study the outcome of blastocysts showing expansion on day 5 and transferred on day 5 or 6, in comparison with those unexpanded and transferred on day 6. STUDY DESIGN: Prospective cohort of 221 women prepared for BET classified into three groups according to timing of blastocyst expansion and day of embryo transfer. Group I; with expanded blastocysts on day 5 having day 5 transfer, group II; with expanded blastocysts on day 5 having day 6 transfer and group III ; with delayed expansion undergoing day 6 BET. RESULTS: Implantation rates, pregnancy rates, ongoing pregnancy rates, and live birth rates in the first 2 groups were almost double the rates in the third group. The figures for implantation rates were 40 % in the first two groups vs. 19 % in the third group (P < 0.05). Pregnancy rates were 60.9 % and 64 % vs. 31.8 % (P < 0.05) and ongoing pregnancy/ live-birth rates were 52.3 % & 56 % vs. 27.3 %. CONCLUSION: The current study reports better implantation and pregnancy rates with earlier expanding blastocysts regardless of the time of transfer.
Authors: Bruce S Shapiro; Said T Daneshmand; Forest C Garner; Martha Aguirre; Richard Ross Journal: Fertil Steril Date: 2007-01-16 Impact factor: 7.329
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Authors: Bruce S Shapiro; Said T Daneshmand; Forest C Garner; Martha Aguirre; Shyni Thomas Journal: Fertil Steril Date: 2007-10-01 Impact factor: 7.329
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