Literature DB >> 22842956

Three- and four-level anterior cervical discectomy and fusion with a PEEK cage and plate construct.

Kyung-Jin Song1, Sun-Jung Yoon, Kwang-Bok Lee.   

Abstract

INTRODUCTION: Three- or four-level anterior cervical discectomy and fusion with autograft and plate fixation have demonstrated relatively good fusion rates and outcomes, but donor site morbidity and the limitations of autograft harvest remain problematic. The purpose of this study is to assess the radiographic and clinical outcomes of three- or four-level anterior cervical discectomy and fusion with a PEEK cage and plate construct.
METHODS: This retrospective review included 43 consecutive patients who underwent three- or four-level anterior cervical discectomy and fusion with a PEEK cage and plate construct (three level: 39 cases, four level: 4 cases). The fusion rate, time to fusion, Cobb angle and disc height were assessed radiographically. Clinical outcomes were evaluated with the VAS, NDI, and SF36 scores. Complications were also recorded.
RESULTS: Solid fusion was achieved in all the patients, and mean time to fusion was 13.7 ± 5.1 weeks. The postoperative Cobb angle, lordotic angle, and disc height (5.6°, 10.5° and 3.15 mm, respectively) increased significantly compared to preoperative values (p = 0.038, p = 0.032, and p = 0.0004, respectively), and these improvements were maintained through final follow-up. The postoperative NDI (17.2), VAS (2.8), and SF36 (13.1) scores increased significantly compared to the preoperative scores (p = 0.026, p = 0.0007 and p = 0.041, respectively). Complications included three cases of respiratory difficulty, four cases of dysphagia and one case of hoarseness. There were no cases of donor site morbidity.
CONCLUSIONS: Three- or four-level anterior cervical discectomy and fusion with a PEEK cage, and plate construct provide good clinical and radiographic outcomes including high fusion rates, low complication rates, low donor site morbidity, and good maintenance of the lordotic angle and disc height in the treatment of multilevel cervical spondylosis.

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Mesh:

Year:  2012        PMID: 22842956      PMCID: PMC3508232          DOI: 10.1007/s00586-012-2447-0

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  34 in total

1.  Preliminary experience of carbon fibre cage prostheses for treatment of cervical spine disorders.

Authors:  N S Brooke; A W Rorke; A T King; R W Gullan
Journal:  Br J Neurosurg       Date:  1997-06       Impact factor: 1.596

2.  Increased fusion rates with cervical plating for three-level anterior cervical discectomy and fusion.

Authors:  J C Wang; P W McDonough; L E Kanim; K K Endow; R B Delamarter
Journal:  Spine (Phila Pa 1976)       Date:  2001-03-15       Impact factor: 3.468

3.  Iliac bone grafting: review of 160 consecutive cases.

Authors:  E E Keller; W W Triplett
Journal:  J Oral Maxillofac Surg       Date:  1987-01       Impact factor: 1.895

4.  Incidence of dysphagia after anterior cervical spine surgery: a prospective study.

Authors:  Rajesh Bazaz; Michael J Lee; Jung U Yoo
Journal:  Spine (Phila Pa 1976)       Date:  2002-11-15       Impact factor: 3.468

5.  Use of cylindrical titanium mesh and locking plates in anterior cervical fusion. Technical note.

Authors:  K Das; W T Couldwell; G Sava; R F Taddonio
Journal:  J Neurosurg       Date:  2001-01       Impact factor: 5.115

6.  Preliminary experience using a polyetheretherketone (PEEK) cage in the treatment of cervical disc disease.

Authors:  Der-Yang Cho; Wen-Rei Liau; Wen-Yen Lee; Jung-Tung Liu; Chung-Lian Chiu; Pon-Chun Sheu
Journal:  Neurosurgery       Date:  2002-12       Impact factor: 4.654

7.  Subsidence of stand-alone cervical cages in anterior interbody fusion: warning.

Authors:  Erol Gercek; Vincent Arlet; Josee Delisle; Dante Marchesi
Journal:  Eur Spine J       Date:  2003-06-21       Impact factor: 3.134

8.  Pseudarthrosis rate after allograft posterior lumbar interbody fusion with pedicle screw and plate fixation.

Authors:  J W Brantigan
Journal:  Spine (Phila Pa 1976)       Date:  1994-06-01       Impact factor: 3.468

9.  Iliac crest bone graft harvest donor site morbidity. A statistical evaluation.

Authors:  J C Banwart; M A Asher; R S Hassanein
Journal:  Spine (Phila Pa 1976)       Date:  1995-05-01       Impact factor: 3.468

10.  The Neck Disability Index: a study of reliability and validity.

Authors:  H Vernon; S Mior
Journal:  J Manipulative Physiol Ther       Date:  1991-09       Impact factor: 1.437

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  14 in total

1.  Multi- versus single-level anterior cervical discectomy and fusion: comparing sagittal alignment, early adjacent segment degeneration, and clinical outcomes.

Authors:  Bryce A Basques; Philip K Louie; Jeremy Mormol; Jannat M Khan; Kamran Movassaghi; Justin C Paul; Arya Varthi; Edward J Goldberg; Howard S An
Journal:  Eur Spine J       Date:  2018-06-26       Impact factor: 3.134

Review 2.  Zero-profile anchored cage reduces risk of postoperative dysphagia compared with cage with plate fixation after anterior cervical discectomy and fusion.

Authors:  ShanWen Xiao; ZhuDe Liang; Wu Wei; JinPei Ning
Journal:  Eur Spine J       Date:  2016-12-21       Impact factor: 3.134

3.  Anterior surgical treatment of cervical spondylotic myelopathy: review article.

Authors:  John C Quinn; Paul D Kiely; Darren R Lebl; Alexander P Hughes
Journal:  HSS J       Date:  2014-08-08

4.  Comparison of titanium and polyetheretherketone (PEEK) cages in the surgical treatment of multilevel cervical spondylotic myelopathy: a prospective, randomized, control study with over 7-year follow-up.

Authors:  Yu Chen; Xinwei Wang; Xuhua Lu; Lili Yang; Haisong Yang; Wen Yuan; Deyu Chen
Journal:  Eur Spine J       Date:  2013-04-09       Impact factor: 3.134

5.  Outcomes Evaluation of Zero-Profile Devices Compared to Stand-Alone PEEK Cages for the Treatment of Three- and Four-Level Cervical Disc Disease.

Authors:  Peter C Gerszten; Erin Paschel; Hazem Mashaly; Hatem Sabry; Hasan Jalalod'din; Khaled Saoud
Journal:  Cureus       Date:  2016-09-10

6.  Prevalence of complications after surgery in treatment for cervical compressive myelopathy: A meta-analysis for last decade.

Authors:  Tao Wang; Xiao-Ming Tian; Si-Kai Liu; Hui Wang; Ying-Ze Zhang; Wen-Yuan Ding
Journal:  Medicine (Baltimore)       Date:  2017-03       Impact factor: 1.889

7.  Clinical and radiological outcomes of a cervical cage with integrated fixation.

Authors:  Nicolas Lonjon; Emmanuel Favreul; Jean Huppert; Eric Lioret; Manuel Delhaye; Ramzi Mraidi
Journal:  Medicine (Baltimore)       Date:  2019-01       Impact factor: 1.817

8.  Clinical outcomes for anterior cervical discectomy and fusion with silicon nitride spine cages: a multicenter study.

Authors:  Graham C Calvert; George VanBuren Huffmon; William M Rambo; Micah W Smith; Bryan J McEntire; B Sonny Bal
Journal:  J Spine Surg       Date:  2019-12

9.  A comparison of anterior cervical discectomy and fusion combined with cervical disc arthroplasty and cervical disc arthroplasty for the treatment of skip-level cervical degenerative disc disease: A retrospective study.

Authors:  Ting-Kui Wu; Bei-Yu Wang; Ming-Dan Deng; Ying Hong; Xin Rong; Hua Chen; Yang Meng; Hao Liu
Journal:  Medicine (Baltimore)       Date:  2017-10       Impact factor: 1.817

Review 10.  Radiological Fusion Criteria of Postoperative Anterior Cervical Discectomy and Fusion: A Systematic Review.

Authors:  Masahito Oshina; Yasushi Oshima; Sakae Tanaka; K Daniel Riew
Journal:  Global Spine J       Date:  2018-02-11
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