BACKGROUND AND OBJECTIVES: The extent to which racial and socioeconomic disparities in access to kidney transplantation are related to not being assessed for transplant suitability before or shortly after the time of initiation of dialysis is not known. The aims of this study were to determine whether there were disparities based on race, ethnicity, or type of insurance in delayed assessment for transplantation and whether delayed assessment was associated with lower likelihood of waitlisting and kidney transplantation. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This retrospective cohort study used data from the US Renal Data System and included 426,489 adult patients beginning dialysis in the United States between January 1, 2005 and September 30, 2009 without prior kidney transplant. RESULTS: Overall, 12.5% of patients had reportedly not been assessed for transplantation. Patients without private insurance were more likely to be reported as not assessed (multivariable adjusted odds ratio=1.33, 95% confidence interval=1.28-1.40 for Medicaid), with a pronounced racial disparity but no ethnic disparity among patients aged 18 to <35 years (odds ratio=1.27, 95% confidence interval=1.13-1.43; P<0.001 for interaction with age). Not being assessed for transplant around the time of dialysis initiation was associated with lower likelihood of waitlisting in multivariable analysis (hazard ratio=0.59, 95% confidence interval=0.57-0.62 in the first year) and transplantation (hazard ratio=0.46, 95% confidence interval=0.41-0.51 in the first year), especially within the first 2 years. CONCLUSIONS: Racial and insurance-related disparities in transplant assessment potentially delay transplantation, particularly among younger patients.
BACKGROUND AND OBJECTIVES: The extent to which racial and socioeconomic disparities in access to kidney transplantation are related to not being assessed for transplant suitability before or shortly after the time of initiation of dialysis is not known. The aims of this study were to determine whether there were disparities based on race, ethnicity, or type of insurance in delayed assessment for transplantation and whether delayed assessment was associated with lower likelihood of waitlisting and kidney transplantation. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This retrospective cohort study used data from the US Renal Data System and included 426,489 adult patients beginning dialysis in the United States between January 1, 2005 and September 30, 2009 without prior kidney transplant. RESULTS: Overall, 12.5% of patients had reportedly not been assessed for transplantation. Patients without private insurance were more likely to be reported as not assessed (multivariable adjusted odds ratio=1.33, 95% confidence interval=1.28-1.40 for Medicaid), with a pronounced racial disparity but no ethnic disparity among patients aged 18 to <35 years (odds ratio=1.27, 95% confidence interval=1.13-1.43; P<0.001 for interaction with age). Not being assessed for transplant around the time of dialysis initiation was associated with lower likelihood of waitlisting in multivariable analysis (hazard ratio=0.59, 95% confidence interval=0.57-0.62 in the first year) and transplantation (hazard ratio=0.46, 95% confidence interval=0.41-0.51 in the first year), especially within the first 2 years. CONCLUSIONS: Racial and insurance-related disparities in transplant assessment potentially delay transplantation, particularly among younger patients.
Authors: A M Epstein; J Z Ayanian; J H Keogh; S J Noonan; N Armistead; P D Cleary; J S Weissman; J A David-Kasdan; D Carlson; J Fuller; D Marsh; R M Conti Journal: N Engl J Med Date: 2000-11-23 Impact factor: 91.245
Authors: R A Wolfe; V B Ashby; E L Milford; A O Ojo; R E Ettenger; L Y Agodoa; P J Held; F K Port Journal: N Engl J Med Date: 1999-12-02 Impact factor: 91.245
Authors: R A Wolfe; V B Ashby; E L Milford; W E Bloembergen; L Y Agodoa; P J Held; F K Port Journal: Am J Kidney Dis Date: 2000-11 Impact factor: 8.860
Authors: L Ebony Boulware; Lucy A Meoni; Nancy E Fink; Rulan S Parekh; W H Linda Kao; Michael J Klag; Neil R Powe Journal: Am J Transplant Date: 2005-06 Impact factor: 8.086
Authors: R E Patzer; J P Perryman; J D Schrager; S Pastan; S Amaral; J A Gazmararian; M Klein; N Kutner; W M McClellan Journal: Am J Transplant Date: 2012-01-10 Impact factor: 8.086
Authors: John Z Ayanian; Paul D Cleary; Joseph H Keogh; Susan J Noonan; Jo Ann David-Kasdan; Arnold M Epstein Journal: Am J Kidney Dis Date: 2004-02 Impact factor: 8.860
Authors: R W Evans; D L Manninen; L P Garrison; L G Hart; C R Blagg; R A Gutman; A R Hull; E G Lowrie Journal: N Engl J Med Date: 1985-02-28 Impact factor: 91.245
Authors: Keren Ladin; Joanna Emerson; Zeeshan Butt; Elisa J Gordon; Douglas W Hanto; Jennifer Perloff; Norman Daniels; Tara A Lavelle Journal: J Med Ethics Date: 2018-06-28 Impact factor: 2.903
Authors: Marlena Maziarz; R Anthony Black; Christine T Fong; Jonathan Himmelfarb; Glenn M Chertow; Yoshio N Hall Journal: J Am Soc Nephrol Date: 2014-12-04 Impact factor: 10.121
Authors: Laura C Plantinga; Cristina Drenkard; Rachel E Patzer; Mitchel Klein; Michael R Kramer; Stephen Pastan; S Sam Lim; William M McClellan Journal: Arthritis Rheumatol Date: 2015-03 Impact factor: 10.995
Authors: Meera N Harhay; Ryan M McKenna; Suzanne M Boyle; Karthik Ranganna; Lissa Levin Mizrahi; Stephen Guy; Gregory E Malat; Gary Xiao; David J Reich; Michael O Harhay Journal: Clin J Am Soc Nephrol Date: 2018-06-21 Impact factor: 8.237
Authors: Sarah Streeter Hutcheson; Victoria Phillips; Rachel Patzer; Andrew Smith; J David Vega; Alanna A Morris Journal: Clin Transplant Date: 2018-07-11 Impact factor: 2.863
Authors: Michelle M O'Shaughnessy; Maria E Montez-Rath; Richard A Lafayette; Wolfgang C Winkelmayer Journal: Nephrol Dial Transplant Date: 2015-11-25 Impact factor: 5.992
Authors: Derek A DuBay; Paul A MacLennan; Rhiannon D Reed; Brittany A Shelton; David T Redden; Mona Fouad; Michelle Y Martin; Stephen H Gray; Jared A White; Devin E Eckhoff; Jayme E Locke Journal: J Am Coll Surg Date: 2016-07-25 Impact factor: 6.113