Literature DB >> 11087884

Racial disparities in access to renal transplantation--clinically appropriate or due to underuse or overuse?

A M Epstein1, J Z Ayanian, J H Keogh, S J Noonan, N Armistead, P D Cleary, J S Weissman, J A David-Kasdan, D Carlson, J Fuller, D Marsh, R M Conti.   

Abstract

BACKGROUND: Despite abundant evidence of racial disparities in the use of surgical procedures, it is uncertain whether these disparities reflect racial differences in clinical appropriateness or overuse or underuse of inappropriate care.
METHODS: We performed a literature review and used an expert panel to develop criteria for determining the appropriateness of renal transplantation for patients with end-stage renal disease. Using data from five states and the District of Columbia on patients who had started to undergo dialysis in 1996 or 1997, we selected a random sample of 1518 patients (age range, 18 to 54 years), stratified according to race and sex. We classified the appropriateness of patients as data on candidates for transplantation and analyzed rates of referral to a transplantation center for evaluation, placement on a waiting list, and receipt of a transplant according to race.
RESULTS: Black patients were less likely than white patients to be rated as appropriate candidates for transplantation according to appropriateness criteria based on expert opinion (71 blacks [9.0 percent] vs. 152 whites [20.9 percent]) and were more likely to have had incomplete evaluations (368 [46.5 percent] vs. 282 [38.8 percent], P<0.001 for the overall chi-square). Among patients considered to be appropriate candidates for transplantation, blacks were less likely than whites to be referred for evaluation, according to the chart review (90.1 percent vs. 98.0 percent, P=0.008), to be placed on a waiting list (71.0 percent vs. 86.7 percent, P=0.007), or to undergo transplantation (16.9 percent vs. 52.0 percent, P<0.001). Among patients classified as inappropriate candidates, whites were more likely than blacks to be referred for evaluation (57.8 percent vs. 38.4 percent), to be placed on a waiting list (30.9 percent vs. 17.4 percent), and to undergo transplantation (10.3 percent vs. 2.2 percent, P<0.001 for all three comparisons).
CONCLUSIONS: Racial disparities in rates of renal transplantation stem from differences in clinical characteristics that affect appropriateness as well as from underuse of transplantation among blacks and overuse among whites. Reducing racial disparities will require efforts to distinguish their specific causes and the development of interventions tailored to address them.

Entities:  

Keywords:  Empirical Approach; Health Care and Public Health; Professional Patient Relationship

Mesh:

Year:  2000        PMID: 11087884      PMCID: PMC4598055          DOI: 10.1056/NEJM200011233432106

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


  34 in total

1.  What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes.

Authors:  J Zhang; K F Yu
Journal:  JAMA       Date:  1998-11-18       Impact factor: 56.272

2.  Effects of changes in the criteria for nationally shared kidney transplants for HLA-matched patients.

Authors:  Y Hata; J M Cecka; S Takemoto; M Ozawa; Y W Cho; P I Terasaki
Journal:  Transplantation       Date:  1998-01-27       Impact factor: 4.939

3.  Does inappropriate use explain geographic variations in the use of health care services? A study of three procedures.

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Journal:  JAMA       Date:  1987-11-13       Impact factor: 56.272

4.  The appropriateness of performing coronary artery bypass surgery.

Authors:  C M Winslow; J B Kosecoff; M Chassin; D E Kanouse; R H Brook
Journal:  JAMA       Date:  1988 Jul 22-29       Impact factor: 56.272

5.  Racial differences in the use of invasive cardiovascular procedures in the Department of Veterans Affairs medical system.

Authors:  J Whittle; J Conigliaro; C B Good; R P Lofgren
Journal:  N Engl J Med       Date:  1993-08-26       Impact factor: 91.245

6.  How coronary angiography is used. Clinical determinants of appropriateness.

Authors:  M R Chassin; J Kosecoff; D H Solomon; R H Brook
Journal:  JAMA       Date:  1987-11-13       Impact factor: 56.272

7.  Access to kidney transplantation. Has the United States eliminated income and racial differences?

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Journal:  Arch Intern Med       Date:  1988-12

8.  The effect of race and sex on physicians' recommendations for cardiac catheterization.

Authors:  K A Schulman; J A Berlin; W Harless; J F Kerner; S Sistrunk; B J Gersh; R Dubé; C K Taleghani; J E Burke; S Williams; J M Eisenberg; J J Escarce
Journal:  N Engl J Med       Date:  1999-02-25       Impact factor: 91.245

9.  Comparison of survival probabilities for dialysis patients vs cadaveric renal transplant recipients.

Authors:  F K Port; R A Wolfe; E A Mauger; D P Berling; K Jiang
Journal:  JAMA       Date:  1993-09-15       Impact factor: 56.272

10.  The quality of life of patients with end-stage renal disease.

Authors:  R W Evans; D L Manninen; L P Garrison; L G Hart; C R Blagg; R A Gutman; A R Hull; E G Lowrie
Journal:  N Engl J Med       Date:  1985-02-28       Impact factor: 91.245

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  162 in total

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Authors:  M C Hollar
Journal:  Psychiatr Q       Date:  2001

2.  Outcomes of treatment for hepatitis C virus infection by primary care providers.

Authors:  Sanjeev Arora; Karla Thornton; Glen Murata; Paulina Deming; Summers Kalishman; Denise Dion; Brooke Parish; Thomas Burke; Wesley Pak; Jeffrey Dunkelberg; Martin Kistin; John Brown; Steven Jenkusky; Miriam Komaromy; Clifford Qualls
Journal:  N Engl J Med       Date:  2011-06-01       Impact factor: 91.245

3.  Racial/ethnic differences in influenza vaccination coverage in high-risk adults.

Authors:  Leonard E Egede; Deyi Zheng
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4.  Prostate cancer and race: variation in diagnosis and treatment.

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Journal:  J Gen Intern Med       Date:  2003-10       Impact factor: 5.128

5.  Healthcare system interventions for inequality in quality: corrective action through evidence-based medicine.

Authors:  William F Owen; Lynda A Szczech; Diane L Frankenfield
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6.  Inflammation and the paradox of racial differences in dialysis survival.

Authors:  Deidra C Crews; Stephen M Sozio; Yongmei Liu; Josef Coresh; Neil R Powe
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Review 7.  Disparities in kidney transplant outcomes: a review.

Authors:  Elisa J Gordon; Daniela P Ladner; Juan Carlos Caicedo; John Franklin
Journal:  Semin Nephrol       Date:  2010-01       Impact factor: 5.299

8.  Community-based health preferences for proctocolectomy: a race comparison.

Authors:  Geoffrey C Nguyen; Anne Tuskey; Theodore M Bayless; Thomas A LaVeist; Steven R Brant
Journal:  Dig Dis Sci       Date:  2007-09-01       Impact factor: 3.199

9.  The Influence of Race/Ethnicity and Education on Family Ratings of the Quality of Dying in the ICU.

Authors:  Janet J Lee; Ann C Long; J Randall Curtis; Ruth A Engelberg
Journal:  J Pain Symptom Manage       Date:  2015-09-16       Impact factor: 3.612

10.  The impact of race and ethnicity on receipt of family planning services in the United States.

Authors:  Sonya Borrero; Eleanor B Schwarz; Mitchell Creinin; Said Ibrahim
Journal:  J Womens Health (Larchmt)       Date:  2009 Jan-Feb       Impact factor: 2.681

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