Literature DB >> 22817888

The dawn of virtual cell biology.

Peter L Freddolino1, Saeed Tavazoie.   

Abstract

To fulfill systems biology's promise of providing fundamental new insights will require the development of quantitative and predictive models of whole cells. In this issue, Karr et al. present the first integrated and dynamic computational model of a bacterium that accounts for all of its components and their interactions.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID: 22817888      PMCID: PMC4430847          DOI: 10.1016/j.cell.2012.07.001

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  9 in total

Review 1.  Enzyme promiscuity: a mechanistic and evolutionary perspective.

Authors:  Olga Khersonsky; Dan S Tawfik
Journal:  Annu Rev Biochem       Date:  2010       Impact factor: 23.643

Review 2.  The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli.

Authors:  Adam M Feist; Bernhard Ø Palsson
Journal:  Nat Biotechnol       Date:  2008-06       Impact factor: 54.908

3.  A whole-cell computational model predicts phenotype from genotype.

Authors:  Jonathan R Karr; Jayodita C Sanghvi; Derek N Macklin; Miriam V Gutschow; Jared M Jacobs; Benjamin Bolival; Nacyra Assad-Garcia; John I Glass; Markus W Covert
Journal:  Cell       Date:  2012-07-20       Impact factor: 41.582

4.  What is flux balance analysis?

Authors:  Jeffrey D Orth; Ines Thiele; Bernhard Ø Palsson
Journal:  Nat Biotechnol       Date:  2010-03       Impact factor: 54.908

5.  A modular minimal cell model: purine and pyrimidine transport and metabolism.

Authors:  M Castellanos; D B Wilson; M L Shuler
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-16       Impact factor: 11.205

6.  Widespread antisense transcription in Escherichia coli.

Authors:  James E Dornenburg; Anne M Devita; Michael J Palumbo; Joseph T Wade
Journal:  MBio       Date:  2010-05-18       Impact factor: 7.867

7.  Noise contributions in an inducible genetic switch: a whole-cell simulation study.

Authors:  Elijah Roberts; Andrew Magis; Julio O Ortiz; Wolfgang Baumeister; Zaida Luthey-Schulten
Journal:  PLoS Comput Biol       Date:  2011-03-10       Impact factor: 4.475

8.  Universally sloppy parameter sensitivities in systems biology models.

Authors:  Ryan N Gutenkunst; Joshua J Waterfall; Fergal P Casey; Kevin S Brown; Christopher R Myers; James P Sethna
Journal:  PLoS Comput Biol       Date:  2007-08-15       Impact factor: 4.475

9.  Dynamic analysis of integrated signaling, metabolic, and regulatory networks.

Authors:  Jong Min Lee; Jong Min Lee; Erwin P Gianchandani; James A Eddy; Jason A Papin
Journal:  PLoS Comput Biol       Date:  2008-05-23       Impact factor: 4.475

  9 in total
  7 in total

Review 1.  Systems biology for molecular life sciences and its impact in biomedicine.

Authors:  Miguel Ángel Medina
Journal:  Cell Mol Life Sci       Date:  2012-08-19       Impact factor: 9.261

Review 2.  Cell-based screening: extracting meaning from complex data.

Authors:  Steven Finkbeiner; Michael Frumkin; Paul D Kassner
Journal:  Neuron       Date:  2015-04-08       Impact factor: 17.173

3.  Discrimination of the SARS-CoV-2 strains using of coloured s-LASCA-imaging of GB-speckles, developed for the gene "S" nucleotide sequences.

Authors:  Onega Ulianova; Yury Saltykov; Sergey Ulyanov; Sergey Zaytsev; Alexander Ulyanov; Valentina Feodorova
Journal:  F1000Res       Date:  2021-06-25

4.  Erythropoietin and organ protection: lessons from negative clinical trials.

Authors:  Ronald G Pearl
Journal:  Crit Care       Date:  2014-09-11       Impact factor: 9.097

5.  Could LASCA-imaging of GB-speckles be applied for a high discrimination and typing of pathogenic bacteria?

Authors:  Onega Ulianova; Sergey Ulyanov; Sergey Zaytsev; Yuriy Saltykov; Alexander Ulyanov; Valentina Feodorova
Journal:  PLoS One       Date:  2021-01-28       Impact factor: 3.240

6.  Digital biology: a new era has begun.

Authors:  Roy D Sleator
Journal:  Bioengineered       Date:  2012 Nov-Dec       Impact factor: 3.269

Review 7.  Integration of 'omics' data in aging research: from biomarkers to systems biology.

Authors:  Jonas Zierer; Cristina Menni; Gabi Kastenmüller; Tim D Spector
Journal:  Aging Cell       Date:  2015-08-30       Impact factor: 9.304

  7 in total

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