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Literature DB >> 22807190

Cell-penetrating peptides as delivery vehicles for a protein-targeted terbium complex.

Shabnam Mohandessi¹, Megha Rajendran, Darren Magda, Lawrence W Miller.

Abstract

Release after transmission: Arginine-rich, cell-penetrating peptides (CPPs) mediate cytoplasmic delivery of trimethoprim (TMP)-terbium complex conjugates and selective, intracellular labeling of E. coli dihydrofolate reductase (eDHFR) fusion proteins. A disulfide bond linking CPP and cargo is reduced following uptake. CPP conjugation can be used to deliver otherwise cell-impermeable, ligand-fluorophore conjugates.

Entities: CellLine Chemical Mutation Species

Mesh：

Substances：

Year: 2012 PMID： 22807190 PMCID： PMC3729426 DOI： 10.1002/chem.201201805

Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236

29 in total

Review 1. Chemical labeling strategies for cell biology.

Authors: Kevin M Marks; Garry P Nolan
Journal: Nat Methods Date: 2006-08 Impact factor: 28.547

2. A comprehensive model for the cellular uptake of cationic cell-penetrating peptides.

Authors: Falk Duchardt; Mariola Fotin-Mleczek; Heinz Schwarz; Rainer Fischer; Roland Brock
Journal: Traffic Date: 2007-07 Impact factor: 6.215

3. An engineered protein tag for multiprotein labeling in living cells.

Authors: Arnaud Gautier; Alexandre Juillerat; Christian Heinis; Ivan Reis Corrêa; Maik Kindermann; Florent Beaufils; Kai Johnsson
Journal: Chem Biol Date: 2008-02

4. Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans.

Authors: Michie Kosuge; Toshihide Takeuchi; Ikuhiko Nakase; Arwyn Tomos Jones; Shiroh Futaki
Journal: Bioconjug Chem Date: 2008-02-13 Impact factor: 4.774

5. HaloTag: a novel protein labeling technology for cell imaging and protein analysis.

Authors: Georgyi V Los; Lance P Encell; Mark G McDougall; Danette D Hartzell; Natasha Karassina; Chad Zimprich; Monika G Wood; Randy Learish; Rachel Friedman Ohana; Marjeta Urh; Dan Simpson; Jacqui Mendez; Kris Zimmerman; Paul Otto; Gediminas Vidugiris; Ji Zhu; Aldis Darzins; Dieter H Klaubert; Robert F Bulleit; Keith V Wood
Journal: ACS Chem Biol Date: 2008-06-20 Impact factor: 5.100

6. Cell-permeable MR contrast agents with increased intracellular retention.

Authors: Paul J Endres; Keith W MacRenaris; Stefan Vogt; Thomas J Meade
Journal: Bioconjug Chem Date: 2008-09-20 Impact factor: 4.774

7. Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells.

Authors: H-L Lee; E A Dubikovskaya; H Hwang; A N Semyonov; H Wang; L R Jones; R J Twieg; W E Moerner; P A Wender
Journal: J Am Chem Soc Date: 2008-06-26 Impact factor: 15.419

8. Improving the photostability of bright monomeric orange and red fluorescent proteins.

Authors: Nathan C Shaner; Michael Z Lin; Michael R McKeown; Paul A Steinbach; Kristin L Hazelwood; Michael W Davidson; Roger Y Tsien
Journal: Nat Methods Date: 2008-05-04 Impact factor: 28.547

9. Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization.

Authors: Damien Maurel; Laëtitia Comps-Agrar; Carsten Brock; Marie-Laure Rives; Emmanuel Bourrier; Mohammed Akli Ayoub; Hervé Bazin; Norbert Tinel; Thierry Durroux; Laurent Prézeau; Eric Trinquet; Jean-Philippe Pin
Journal: Nat Methods Date: 2008-05-18 Impact factor: 28.547

10. Cyanine dye conjugates as probes for live cell imaging.

Authors: Jay R Carreon; Kelly M Stewart; Kerry P Mahon; Stephanie Shin; Shana O Kelley
Journal: Bioorg Med Chem Lett Date: 2007-07-10 Impact factor: 2.823

8 in total

1. Evaluating the performance of time-gated live-cell microscopy with lanthanide probes.

Authors: Megha Rajendran; Lawrence W Miller
Journal: Biophys J Date: 2015-07-21 Impact factor: 4.033

2. Efficient route to pre-organized and linear polyaminopolycarboxylates: Cy-TTHA, Cy-DTPA and mono/di- reactive, tert-butyl protected TTHA/Cy-TTHA.

Authors: Ali Mohamadi; Lawrence W Miller
Journal: Tetrahedron Lett Date: 2017-02-20 Impact factor: 2.415

Cell-penetrating peptides as delivery vehicles for a protein-targeted terbium complex.

Review 1. Chemical labeling strategies for cell biology.

2. A comprehensive model for the cellular uptake of cationic cell-penetrating peptides.

3. An engineered protein tag for multiprotein labeling in living cells.

4. Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans.

5. HaloTag: a novel protein labeling technology for cell imaging and protein analysis.

6. Cell-permeable MR contrast agents with increased intracellular retention.

7. Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells.

8. Improving the photostability of bright monomeric orange and red fluorescent proteins.

9. Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization.

10. Cyanine dye conjugates as probes for live cell imaging.

1. Evaluating the performance of time-gated live-cell microscopy with lanthanide probes.

2. Efficient route to pre-organized and linear polyaminopolycarboxylates: Cy-TTHA, Cy-DTPA and mono/di- reactive, tert-butyl protected TTHA/Cy-TTHA.

3. Cytoplasmic delivery and selective, multicomponent labeling with oligoarginine-linked protein tags.

4. Bright and stable luminescent probes for target engagement profiling in live cells.

5. Polarization and symmetry of electronic transitions in long fluorescence lifetime triangulenium dyes.

Review 6. Lanthanide-based imaging of protein-protein interactions in live cells.

7. Effect of lanthanide complex structure on cell viability and association.

8. Transportan 10 improves the anticancer activity of cisplatin.