Literature DB >> 22789533

To the rescue: the Fanconi anemia genome stability pathway salvages replication forks.

George-Lucian Moldovan1, Alan D D'Andrea.   

Abstract

DNA damage can arrest replication forks during S phase. Failure to stabilize and restart arrested forks results in fork collapse and genomic instability. In this issue of Cancer Cell, Schlacher et al. show that the Fanconi anemia and BRCA2 tumor suppressor pathways cooperate to protect stalled replication forks from degradation.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22789533      PMCID： PMC3406730          DOI： 10.1016/j.ccr.2012.06.006

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  10 in total

Review 1.  The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA.

Authors:  Gerry P Crossan; Ketan J Patel
Journal:  J Pathol       Date:  2011-10-25       Impact factor: 7.996

2.  Ten genes for inherited breast cancer.

Authors:  Tom Walsh; Mary-Claire King
Journal:  Cancer Cell       Date:  2007-02       Impact factor: 31.743

Review 3.  The consequences of Rad51 overexpression for normal and tumor cells.

Authors:  Hannah L Klein
Journal:  DNA Repair (Amst)       Date:  2008-02-01

4.  Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

Authors:  Katharina Schlacher; Nicole Christ; Nicolas Siaud; Akinori Egashira; Hong Wu; Maria Jasin
Journal:  Cell       Date:  2011-05-13       Impact factor: 41.582

5.  Inhibition of homologous recombination by the PCNA-interacting protein PARI.

Authors:  George-Lucian Moldovan; Donniphat Dejsuphong; Mark I R Petalcorin; Kay Hofmann; Shunichi Takeda; Simon J Boulton; Alan D D'Andrea
Journal:  Mol Cell       Date:  2011-12-06       Impact factor: 17.970

6.  A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

Authors:  Katharina Schlacher; Hong Wu; Maria Jasin
Journal:  Cancer Cell       Date:  2012-07-10       Impact factor: 31.743

Review 7.  Regulation of homologous recombination in eukaryotes.

Authors:  Wolf-Dietrich Heyer; Kirk T Ehmsen; Jie Liu
Journal:  Annu Rev Genet       Date:  2010       Impact factor: 16.830

8.  A chemical compound that stimulates the human homologous recombination protein RAD51.

Authors:  Krishanthi Jayathilaka; Sean D Sheridan; Tyler D Bold; Katarzyna Bochenska; Hillary L Logan; Ralph R Weichselbaum; Douglas K Bishop; Philip P Connell
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-07       Impact factor: 11.205

9.  Biallelic inactivation of BRCA2 in Fanconi anemia.

Authors:  Niall G Howlett; Toshiyasu Taniguchi; Susan Olson; Barbara Cox; Quinten Waisfisz; Christine De Die-Smulders; Nicole Persky; Markus Grompe; Hans Joenje; Gerard Pals; Hideyuki Ikeda; Edward A Fox; Alan D D'Andrea
Journal:  Science       Date:  2002-06-13       Impact factor: 47.728

10.  Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways.

Authors:  Shobbir Hussain; James B Wilson; Annette L Medhurst; James Hejna; Emily Witt; Sahana Ananth; Adelina Davies; Jean-Yves Masson; Robb Moses; Stephen C West; Johan P de Winter; Alan Ashworth; Nigel J Jones; Christopher G Mathew
Journal:  Hum Mol Genet       Date:  2004-04-28       Impact factor: 6.150
  10 in total
  14 in total

1.  Replication Protein A (RPA) deficiency activates the Fanconi anemia DNA repair pathway.

Authors:  Seok-Won Jang; Jin Ki Jung; Jung Min Kim
Journal:  Cell Cycle       Date:  2016-07-11       Impact factor: 4.534

2.  The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.

Authors:  Jennifer M Mason; Ishita Das; Martin Arlt; Neil Patel; Stephanie Kraftson; Thomas W Glover; JoAnn M Sekiguchi
Journal:  Hum Mol Genet       Date:  2013-07-17       Impact factor: 6.150

3.  ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair.

Authors:  Kumar Somyajit; Shivakumar Basavaraju; Ralph Scully; Ganesh Nagaraju
Journal:  Mol Cell Biol       Date:  2013-02-25       Impact factor: 4.272

4.  The BRUCE-ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development.

Authors:  Chunmin Ge; Chrystelle L Vilfranc; Lixiao Che; Raj K Pandita; Shashank Hambarde; Paul R Andreassen; Liang Niu; Olugbenga Olowokure; Shimul Shah; Susan E Waltz; Lee Zou; Jiang Wang; Tej K Pandita; Chunying Du
Journal:  Hepatology       Date:  2019-03-13       Impact factor: 17.425

5.  Loss of the transforming growth factor-β effector β2-Spectrin promotes genomic instability.

Authors:  Jian Chen; Vivek Shukla; Patrizia Farci; Jaclyn Andricovich; Wilma Jogunoori; Lawrence N Kwong; Lior H Katz; Kirti Shetty; Asif Rashid; Xiaoping Su; Jon White; Lei Li; Alan Yaoqi Wang; Boris Blechacz; Gottumukkala S Raju; Marta Davila; Bao-Ngoc Nguyen; John R Stroehlein; Junjie Chen; Sang Soo Kim; Heather Levin; Keigo Machida; Hidekazu Tsukamoto; Peter Michaely; Alexandros Tzatsos; Bibhuti Mishra; Richard Amdur; Lopa Mishra
Journal:  Hepatology       Date:  2016-12-24       Impact factor: 17.425

6.  β2-spectrin depletion impairs DNA damage repair.

Authors:  Nobuo Horikoshi; Raj K Pandita; Kalpana Mujoo; Shashank Hambarde; Dharmendra Sharma; Abid R Mattoo; Sharmistha Chakraborty; Vijaya Charaka; Clayton R Hunt; Tej K Pandita
Journal:  Oncotarget       Date:  2016-06-07

Review 7.  Recovery from the DNA Replication Checkpoint.

Authors:  Indrajit Chaudhury; Deanna M Koepp
Journal:  Genes (Basel)       Date:  2016-10-28       Impact factor: 4.096

8.  MT1-MMP-dependent ECM processing regulates laminB1 stability and mediates replication fork restart.

Authors:  Varsha Thakur; Juliano Tiburcio de Freitas; Yuan Li; Keman Zhang; Alyssa Savadelis; Barbara Bedogni
Journal:  PLoS One       Date:  2021-07-08       Impact factor: 3.240

9.  PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[α]indene Derivative in Lung Cancer Cells.

Authors:  Kumar Sanjiv; Chi-Wei Chen; Rajesh Kakadiya; Satishkumar Tala; Sharda Suman; Ming-Hsi Wu; Yen-Hui Chen; Tsann-Long Su; Te-Chang Lee
Journal:  Transl Oncol       Date:  2014-03-04       Impact factor: 4.243

10.  Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells.

Authors:  Emilie Renaud; Aurelia Barascu; Filippo Rosselli
Journal:  Nucleic Acids Res       Date:  2015-10-07       Impact factor: 16.971
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