Literature DB >> 22770235

Reprogramming a broken heart.

Emil M Hansson1, Kenneth R Chien.   

Abstract

Fibrosis resulting from cardiac injury presents a major challenge to restoring heart function after myocardial infarction. Two recent papers in Nature report successful in vivo reprogramming of fibroblasts to cardiomyocytes in injured mouse hearts (Qian et al., 2012; Song et al., 2012), resulting in improved cardiac function and reduced scar formation.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22770235     DOI： 10.1016/j.stem.2012.06.014

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  7 in total

1.  The years of the monkey.

Authors:  Xiaojun Lian; Kenneth R Chien
Journal:  Cell Res       Date:  2013-08-20       Impact factor: 25.617

Review 2.  Transdifferentiation of Fibroblasts by Defined Factors.

Authors:  Zhiliang Zhao; Mengyao Xu; Meng Wu; Xiaocheng Tian; Cuiping Zhang; Xiaobing Fu
Journal:  Cell Reprogram       Date:  2015-06       Impact factor: 1.987

3.  Induction of human cardiomyocyte-like cells from fibroblasts by defined factors.

Authors:  Rie Wada; Naoto Muraoka; Kohei Inagawa; Hiroyuki Yamakawa; Kazutaka Miyamoto; Taketaro Sadahiro; Tomohiko Umei; Ruri Kaneda; Tomoyuki Suzuki; Kaichiro Kamiya; Shugo Tohyama; Shinsuke Yuasa; Kiyokazu Kokaji; Ryo Aeba; Ryohei Yozu; Hiroyuki Yamagishi; Toshio Kitamura; Keiichi Fukuda; Masaki Ieda
Journal:  Proc Natl Acad Sci U S A       Date:  2013-07-16       Impact factor: 11.205

4.  High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.

Authors:  Yuanbiao Zhao; Pilar Londono; Yingqiong Cao; Emily J Sharpe; Catherine Proenza; Rebecca O'Rourke; Kenneth L Jones; Mark Y Jeong; Lori A Walker; Peter M Buttrick; Timothy A McKinsey; Kunhua Song
Journal:  Nat Commun       Date:  2015-09-10       Impact factor: 14.919

5.  Acquisition of a quantitative, stoichiometrically conserved ratiometric marker of maturation status in stem cell-derived cardiac myocytes.

Authors:  Fikru B Bedada; Sunny S-K Chan; Stefania K Metzger; Liying Zhang; Jianyi Zhang; Daniel J Garry; Timothy J Kamp; Michael Kyba; Joseph M Metzger
Journal:  Stem Cell Reports       Date:  2014-09-04       Impact factor: 7.765

Review 6.  Accelerated neuronal aging in vitro ∼melting watch ∼.

Authors:  Emi Inagaki; Sho Yoshimatsu; Hideyuki Okano
Journal:  Front Aging Neurosci       Date:  2022-08-09       Impact factor: 5.702

7.  Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes.

Authors:  Jamie L Ifkovits; Russell C Addis; Jonathan A Epstein; John D Gearhart
Journal:  PLoS One       Date:  2014-02-26       Impact factor: 3.240
  7 in total

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