| Literature DB >> 23958583 |
Xiaojun Lian1, Kenneth R Chien.
Abstract
The fact that mammals are diploid sets a barrier to rapidly understand the function of non-coding and coding genes in the genome. Recently, Yang et al. reported successful derivation of monkey haploid embryonic stem cells from parthenotes, which provide an effective platform for studying mammalian gene function and enable reverse genetic screening of genes for recessive phenotypes in monkeys.Entities:
Mesh:
Year: 2013 PMID: 23958583 PMCID: PMC3790233 DOI: 10.1038/cr.2013.111
Source DB: PubMed Journal: Cell Res ISSN: 1001-0602 Impact factor: 25.617