Literature DB >> 22747620

Dietary supplements and hypertension: potential benefits and precautions.

Carly B Rasmussen1, James K Glisson, Deborah S Minor.   

Abstract

Dietary supplements (DSs) are used extensively in the general population and many are promoted for the natural treatment and management of hypertension. Patients with hypertension often choose to use these products either in addition to or instead of pharmacologic antihypertensive agents. Because of the frequent use of DS, both consumers and health care providers should be aware of the considerable issues surrounding these products and factors influencing both efficacy and safety. In this review of the many DSs promoted for the management of hypertension, 4 products with evidence of possible benefits (coenzyme Q10, fish oil, garlic, vitamin C) and 4 that were consistently associated with increasing blood pressure were found (ephedra, Siberian ginseng, bitter orange, licorice). The goals and objectives of this review are to discuss the regulation of DS, evaluate the efficacy of particular DS in the treatment of hypertension, and highlight DS that may potentially increase blood pressure.
© 2012 Wiley Periodicals, Inc.

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Year:  2012        PMID: 22747620      PMCID: PMC8108971          DOI: 10.1111/j.1751-7176.2012.00642.x

Source DB:  PubMed          Journal:  J Clin Hypertens (Greenwich)        ISSN: 1524-6175            Impact factor:   3.738


  22 in total

1.  Therapy with garlic: results of a placebo-controlled, double-blind study.

Authors:  G Vorberg; B Schneider
Journal:  Br J Clin Pract Suppl       Date:  1990-08

2.  Treatment of hypertension with ascorbic acid.

Authors:  S J Duffy; N Gokce; M Holbrook; A Huang; B Frei; J F Keaney; J A Vita
Journal:  Lancet       Date:  1999-12-11       Impact factor: 79.321

3.  The effect of fish oil on hypertension, plasma lipids and hemostasis in hypertensive, obese, dyslipidemic patients with and without diabetes mellitus.

Authors:  C Yosefy; J R Viskoper; A Laszt; R Priluk; E Guita; D Varon; Z Illan; E M Berry; N Savion; Y Adan; G Lugassy; R Schneider; A Raz
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  1999-08       Impact factor: 4.006

4.  Coenzyme Q10 in essential hypertension.

Authors:  V Digiesi; F Cantini; A Oradei; G Bisi; G C Guarino; A Brocchi; F Bellandi; M Mancini; G P Littarru
Journal:  Mol Aspects Med       Date:  1994

5.  A meta-analysis of the effect of garlic on blood pressure.

Authors:  C A Silagy; H A Neil
Journal:  J Hypertens       Date:  1994-04       Impact factor: 4.844

6.  Hypertension and hyperlipidaemia: garlic helps in mild cases.

Authors:  W Auer; A Eiber; E Hertkorn; E Hoehfeld; U Koehrle; A Lorenz; F Mader; W Merx; G Otto; B Schmid-Otto
Journal:  Br J Clin Pract Suppl       Date:  1990-08

7.  Treatment of essential hypertension with coenzyme Q10.

Authors:  P Langsjoen; P Langsjoen; R Willis; K Folkers
Journal:  Mol Aspects Med       Date:  1994

Review 8.  A systematic review on the influence of trial quality on the effect of garlic on blood pressure.

Authors:  S Simons; H Wollersheim; T Thien
Journal:  Neth J Med       Date:  2009-06       Impact factor: 1.422

9.  Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids.

Authors:  C A Haller; N L Benowitz
Journal:  N Engl J Med       Date:  2000-12-21       Impact factor: 176.079

Review 10.  Effect of garlic on blood pressure: a systematic review and meta-analysis.

Authors:  Karin Ried; Oliver R Frank; Nigel P Stocks; Peter Fakler; Thomas Sullivan
Journal:  BMC Cardiovasc Disord       Date:  2008-06-16       Impact factor: 2.298

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  13 in total

1.  Randomised, double-blind, placebo-controlled, assessment of the efficacy and safety of dietary supplements in prehypertension.

Authors:  F Pelliccia; V Pasceri; G Marazzi; A Arrivi; L Cacciotti; G Pannarale; G Speciale; C Greco; C Gaudio
Journal:  J Hum Hypertens       Date:  2017-04-27       Impact factor: 3.012

Review 2.  The clinical significance and costs of herbs and food supplements used by complementary and alternative medicine for the treatment of cardiovascular diseases and hypertension.

Authors:  S G Chrysant
Journal:  J Hum Hypertens       Date:  2015-05-21       Impact factor: 3.012

Review 3.  Dietary supplements in the management of hypertension and diabetes - a review.

Authors:  Anthony Jide Afolayan; Olubunmi Abosede Wintola
Journal:  Afr J Tradit Complement Altern Med       Date:  2014-04-03

Review 4.  The effect of chlorogenic acid on blood pressure: a systematic review and meta-analysis of randomized clinical trials.

Authors:  I J Onakpoya; E A Spencer; M J Thompson; C J Heneghan
Journal:  J Hum Hypertens       Date:  2014-06-19       Impact factor: 3.012

5.  Medicinal Plants with Multiple Effects on Diabetes Mellitus and Its Complications: a Systematic Review.

Authors:  Zeinab Nazarian-Samani; Robert D E Sewell; Zahra Lorigooini; Mahmoud Rafieian-Kopaei
Journal:  Curr Diab Rep       Date:  2018-08-13       Impact factor: 4.810

6.  Some questionable conclusions in the article "Dietary supplements and hypertension: potential benefits and precautions".

Authors:  Sidney J Stohs
Journal:  J Clin Hypertens (Greenwich)       Date:  2012-09-12       Impact factor: 3.738

7.  The effects of unripe grape extract on systemic blood pressure and serum levels of superoxide dismutase, malondialdehyde and nitric oxide in rat.

Authors:  Behzad Zolfaghari; Mostafa Kazemi; Mehdi Nematbakhsh
Journal:  Adv Biomed Res       Date:  2015-05-29

8.  The use of dietary supplements and their association with blood pressure in a large Midwestern cohort.

Authors:  Catherine A McCarty; Richard L Berg; Carla M Rottscheit; Richard A Dart
Journal:  BMC Complement Altern Med       Date:  2013-11-28       Impact factor: 3.659

9.  Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trial.

Authors:  Daniel M Riche; Krista D Riche; Chad T Blackshear; Corey L McEwen; Justin J Sherman; Marion R Wofford; Michael E Griswold
Journal:  Evid Based Complement Alternat Med       Date:  2014-06-25       Impact factor: 2.629

Review 10.  Chocolate--guilty pleasure or healthy supplement?

Authors:  Laura S Latham; Zeb K Hensen; Deborah S Minor
Journal:  J Clin Hypertens (Greenwich)       Date:  2014-02       Impact factor: 3.738

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